PMID:16397293
| Citation |
Riley, M, Abe, T, Arnaud, MB, Berlyn, MK, Blattner, FR, Chaudhuri, RR, Glasner, JD, Horiuchi, T, Keseler, IM, Kosuge, T, Mori, H, Perna, NT, Plunkett, G 3rd, Rudd, KE, Serres, MH, Thomas, GH, Thomson, NR, Wishart, D and Wanner, BL (2006) Escherichia coli K-12: a cooperatively developed annotation snapshot--2005. Nucleic Acids Res. 34:1-9 |
|---|---|
| Abstract |
The goal of this group project has been to coordinate and bring up-to-date information on all genes of Escherichia coli K-12. Annotation of the genome of an organism entails identification of genes, the boundaries of genes in terms of precise start and end sites, and description of the gene products. Known and predicted functions were assigned to each gene product on the basis of experimental evidence or sequence analysis. Since both kinds of evidence are constantly expanding, no annotation is complete at any moment in time. This is a snapshot analysis based on the most recent genome sequences of two E.coli K-12 bacteria. An accurate and up-to-date description of E.coli K-12 genes is of particular importance to the scientific community because experimentally determined properties of its gene products provide fundamental information for annotation of innumerable genes of other organisms. Availability of the complete genome sequence of two K-12 strains allows comparison of their genotypes and mutant status of alleles. |
| Links |
PubMed PMC1325200 Online version:10.1093/nar/gkj405 |
| Keywords |
Congresses as Topic; Cooperative Behavior; Escherichia coli K12/genetics; Escherichia coli Proteins/genetics; Genome, Bacterial; Genomics; Terminology as Topic |
| edit table |
Significance
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This paper describes a reaannotation of E. coli K-12 based on an annotation jamboree held in San Diego involving several E. coli database groups. This paper introduces the ECK numbering system for genes found in both MG1655 and W3110. See the section on unique identifiers.
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