hflX:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

HflX

Synonyms

predicted GTPase[1], B4173[2][1], HflA[2][1], HslX[2][1], HflX[2][1] , ECK4169, hflA, hslX, JW4131, b4173

Product description

putative GTPase; possible regulator of HflKC[2][3]

GTPase, stimulated by 50S subunit binding, function unknown[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005525

GTP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002917

F

Seeded from EcoCyc (v14.0)

complete

GO:0005525

GTP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006073

F

Seeded from EcoCyc (v14.0)

complete

GO:0009408

response to heat

PMID:8349564[5]

IEP: Inferred from Expression Pattern

P

complete

GO:0005525

GTP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0342

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

PMID:19181811[6]

IDA: Inferred from Direct Assay

C

complete

GO:0005622

intracellular

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002917

C

Seeded from EcoCyc (v14.0)

complete

GO:0005525

GTP binding

PMID:19181811[6]

IDA: Inferred from Direct Assay

F

complete

GO:0005524

ATP binding

PMID:19181811[6]

IDA: Inferred from Direct Assay

F

complete

NOT

GO:0030069

lysogeny

PMID:19181811[6]

IMP: Inferred from Mutant Phenotype

P

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MFDRYDAGEQ AVLVHIYFTQ DKDMEDLQEF ESLVSSAGVE ALQVITGSRK APHPKYFVGE
GKAVEIAEAV KATGASVVLF DHALSPAQER NLERLCECRV IDRTGLILDI FAQRARTHEG
KLQVELAQLR HLATRLVRGW THLERQKGGI GLRGPGETQL ETDRRLLRNR IVQIQSRLER
VEKQREQGRQ SRIKADVPTV SLVGYTNAGK STLFNRITEA RVYAADQLFA TLDPTLRRID
VADVGETVLA DTVGFIRHLP HDLVAAFKAT LQETRQATLL LHVIDAADVR VQENIEAVNT
VLEEIDAHEI PTLLVMNKID MLEDFEPRID RDEENKPNRV WLSAQTGAGI PQLFQALTER
LSGEVAQHTL RLPPQEGRLR SRFYQLQAIE KEWMEEDGSV SLQVRMPIVD WRRLCKQEPA
LIDYLI
Length

426

Mol. Wt

48.326 kDa

pI

5.8 (calculated)

Extinction coefficient

32,430 - 32,805 (calc based on 7 Y, 4 W, and 3 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

209..318

PF01926 GTPase of unknown function

PMID:19920124[7]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=hflX taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131995

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948688

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013661

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P25519

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10437

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10437

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948688

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000430

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0432

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Chuang, SE & Blattner, FR (1993) Characterization of twenty-six new heat shock genes of Escherichia coli. J. Bacteriol. 175 5242-52 PubMed
  6. 6.0 6.1 6.2 6.3 Dutta, D et al. (2009) Properties of HflX, an enigmatic protein from Escherichia coli. J. Bacteriol. 191 2307-14 PubMed
  7. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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