hdfR:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

HdfR

Synonyms

DNA-binding transcriptional regulator[1], B4480[2][1], YifA[2][1], HdfR[2][1], YifD[2][1], PssR[2][1] , apeR?, ECK3756, JW5607, yifA, yifD, b4480

Product description

HdfR transcriptional regulator[2]; HdfR transcriptional repressor[3]

Transcriptional regulator of the flhDC operon, hns-dependent; not allelic to pssR[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003700

transcription factor activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01233

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000847

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020890

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

PMID:10913108[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0016566

specific transcriptional repressor activity

PMID:10913108[5]

IDA: Inferred from Direct Assay

F

Seeded from EcoCyc (v14.0)

complete

GO:0032582

negative regulation of gene-specific transcription

PMID:10913108[5]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

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Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MDTELLKTFL EVSRTRHFGR AAESLYLTQS AVSFRIRQLE NQLGVNLFTR HRNNIRLTAA
GEKLLPYAET LMSTWQAARK EVAHTSRHNE FSIGASASLW ECMLNQWLGR LYQNQDAHTG
LQFEARIAQR QSLVKQLHER QLDLLITTEA PKMDEFSSQL LGYFTLALYT SAPSKLKGDL
NYLRLEWGPD FQQHEAGLIG ADEVPILTTS SAELAQQQIA MLNGCTWLPV SWARKKGGLH
TVVDSTTLSR PLYAIWLQNS DKNALIRDLL KINVLDEVY
Length

279

Mol. Wt

31.746 kDa

pI

7.5 (calculated)

Extinction coefficient

50,420 - 50,670 (calc based on 8 Y, 7 W, and 2 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

84..272

PF03466 LysR substrate binding domain

PMID:19920124[6]

Domain

3..62

PF00126 Bacterial regulatory helix-turn-helix protein, lysR family

PMID:19920124[6]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=hdfR taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:49176402

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:2847698

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0174109

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0A8R9

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11449

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11449

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:2847698

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001412

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1418

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 Ko, M & Park, C (2000) H-NS-Dependent regulation of flagellar synthesis is mediated by a LysR family protein. J. Bacteriol. 182 4670-2 PubMed
  6. ↑ 6.0 6.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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