flu:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

Flu

Synonyms

CP4-44 prophage; antigen 43 (Ag43) phase-variable biofilm formation autotransporter[1], B2000[2][1], Agn[2][1], YeeQ[2][1], YzzX[2][1], Flu[2][1], Ag43[2][1] , agn, agn43, ECK1993, JW1982, yeeQ, yzzX, b2000

Product description

CP4-44 prophage; antigen 43 (Ag43) phase-variable biofilm formation autotransporter[2][3]

Antigen 43, phase-variable bipartite outer membrane protein; Ag43; CP4-44 putative defective prophage; affects surface properties, piliation, colonial morphology; unstable gene; alpha and beta subunits formed by cleavage at residue 551[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

ydbH

PMID:16606699[5]

Experiment(s):EBI-1141611

Protein

yehI

PMID:16606699[5]

Experiment(s):EBI-1141611

Protein

gadB

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

groS

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

adhE

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

gapA

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rplT

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

ahpC

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rplJ

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

yfiD

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

pflB

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

dps

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

eno

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

hns

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

wrbA

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rpsN

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

pgk

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rho

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

hupA

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

mdh

PMID:19402753[6]

LCMS(ID Probability):99.2

Protein

rplW

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

hupB

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

cspC

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rpoA

PMID:19402753[6]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

outer membrane

Outer Membrane

PMID:9298646

EchoLocation:flu


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MKRHLNTCYR LVWNHMTGAF VVASELARAR GKRGGVAVAL SLAAVTSLPV LAADIVVHPG
ETVNGGTLAN HDNQIVFGTT NGMTISTGLE YGPDNEANTG GQWVQDGGTA NKTTVTSGGL
QRVNPGGSVS DTVISAGGGQ SLQGRAVNTT LNGGEQWMHE GAIATGTVIN DKGWQVVKPG
TVATDTVVNT GAEGGPDAEN GDTGQFVRGD AVRTTINKNG RQIVRAEGTA NTTVVYAGGD
QTVHGHALDT TLNGGYQYVH NGGTASDTVV NSDGWQIVKN GGVAGNTTVN QKGRLQVDAG
GTATNVTLKQ GGALVTSTAA TVTGINRLGA FSVVEGKADN VVLENGGRLD VLTGHTATNT
RVDDGGTLDV RNGGTATTVS MGNGGVLLAD SGAAVSGTRS DGKAFSIGGG QADALMLEKG
SSFTLNAGDT ATDTTVNGGL FTARGGTLAG TTTLNNGAIL TLSGKTVNND TLTIREGDAL
LQGGSLTGNG SVEKSGSGTL TVSNTTLTQK AVNLNEGTLT LNDSTVTTDV IAQRGTALKL
TGSTVLNGAI DPTNVTLASG ATWNIPDNAT VQSVVDDLSH AGQIHFTSTR TGKFVPATLK
VKNLNGQNGT ISLRVRPDMA QNNADRLVID GGRATGKTIL NLVNAGNSAS GLATSGKGIQ
VVEAINGATT EEGAFVQGNR LQAGAFNYSL NRDSDESWYL RSENAYRAEV PLYASMLTQA
MDYDRIVAGS RSHQTGVNGE NNSVRLSIQG GHLGHDNNGG IARGATPESS GSYGFVRLEG
DLMRTEVAGM SVTAGVYGAA GHSSVDVKDD DGSRAGTVRD DAGSLGGYLN LVHTSSGLWA
DIVAQGTRHS MKASSDNNDF RARGWGWLGS LETGLPFSIT DNLMLEPQLQ YTWQGLSLDD
GKDNAGYVKF GHGSAQHVRA GFRLGSHNDM TFGEGTSSRA PLRDSAKHSV SELPVNWWVQ
PSVIRTFSSR GDMRVGTSTA GSGMTFSPSQ NGTSLDLQAG LEARVRENIT LGVQAGYAHS
VSGSSAEGYN GQATLNVTF
Length

1,039

Mol. Wt

106.822 kDa

pI

6.1 (calculated)

Extinction coefficient

96,830 - 96,955 (calc based on 17 Y, 13 W, and 1 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

motif

1-52

UniProt Manual:Signal Peptides

UniProt:P39180

Domain

738..1023

PF03797 Autotransporter beta-domain

PMID:19920124[7]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=flu taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:49176177

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946540

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0006642

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P39180

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G7080

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12686

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946540

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003666

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2550

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 6.13 6.14 6.15 6.16 6.17 6.18 6.19 6.20 6.21 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  7. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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