fliG:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FliG

Synonyms

flagellar motor switching and energizing component[1], B1939[2][1], FliG[2][1] , ECK1937, flaAII.2, flaBII, JW1923, b1939

Product description

flagellar motor switch protein FliG[2][3];

Component of Flagellar Motor Switch Complex[3]; Flagellar Motor Complex[2][3]; Flagellum[3]

Rotor protein for flagellar motor switching and energizing; role in flagellar assembly[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001539

ciliary or flagellar motility

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000090

P

Seeded from EcoCyc (v14.0)

complete

GO:0001539

ciliary or flagellar motility

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0283

P

Seeded from EcoCyc (v14.0)

complete

GO:0003774

motor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000090

F

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0006935

chemotaxis

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000090

P

Seeded from EcoCyc (v14.0)

complete

GO:0006935

chemotaxis

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0145

P

Seeded from EcoCyc (v14.0)

complete

GO:0071973

bacterial-type flagellar cell motility

PMID:8550421[5]

IMP: Inferred from Mutant Phenotype

P

Fig. 5

complete

GO:0009288

bacterial-type flagellum

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000090

C

Seeded from EcoCyc (v14.0)

complete

GO:0009296

flagellum assembly

PMID:8550421[5]

IMP: Inferred from Mutant Phenotype

P

Table 3

complete

GO:0009288

bacterial-type flagellum

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0975

C

Seeded from EcoCyc (v14.0)

complete

GO:0005515

protein binding

PMID:17085573[6]

IPI: Inferred from Physical Interaction

UniProtKB:P06974


F

Fig. 4

complete

GO:0009425

bacterial-type flagellum basal body

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0142

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0005515

protein binding

PMID:8604139[7]

IPI: Inferred from Physical Interaction

UniProtKB:P25798


F

Fig. 3

complete

GO:0005515

protein binding

PMID:8631704[8]

IPI: Inferred from Physical Interaction

UniProtKB:P06974


F

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of Flagellar Motor Switch Complex

could be indirect

Protein

nadE

PMID:16606699[9]

Experiment(s):EBI-1141425

Protein

uvrY

PMID:16606699[9]

Experiment(s):EBI-1141425

Protein

rplB

PMID:16606699[9]

Experiment(s):EBI-1141425

Protein

rsuA

PMID:16606699[9]

Experiment(s):EBI-1141425

Protein

mukB

PMID:16606699[9]

Experiment(s):EBI-1141425

Protein

rplD

PMID:16606699[9]

Experiment(s):EBI-1141425

Protein

Subunits of Flagellar Motor Complex

could be indirect

Protein

Subunits of Flagellum

could be indirect


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MSNLTGTDKS VILLMTIGED RAAEVFKHLS QREVQTLSAA MANVTQISNK QLTDVLAEFE
QEAEQFAALN INANDYLRSV LVKALGEERA ASLLEDILET RDTASGIETL NFMEPQSAAD
LIRDEHPQII ATILVHLKRA QAADILALFD ERLRHDVMLR IATFGGVQPA ALAELTEVLN
GLLDGQNLKR SKMGGVRTAA EIINLMKTQQ EEAVITAVRE FDGELAQKII DEMFLFENLV
DVDDRSIQRL LQEVDSESLL IALKGAEQPL REKFLRNMSQ RAADILRDDL ANRGPVRLSQ
VENEQKAILL IVRRLAETGE MVIGSGEDTY V
Length

331

Mol. Wt

36.776 kDa

pI

4.5 (calculated)

Extinction coefficient

2,980 (calc based on 2 Y, 0 W, and 0 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

215..324

PF01706 FliG C-terminal domain

PMID:19920124[10]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=fliG taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129886

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946451

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0006456

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0ABZ1

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11654

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11654

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946451

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001598

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1607

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 Lloyd, SA et al. (1996) Torque generation in the flagellar motor of Escherichia coli: evidence of a direct role for FliG but not for FliM or FliN. J. Bacteriol. 178 223-31 PubMed
  6. Brown, PN et al. (2007) Mutational analysis of the flagellar protein FliG: sites of interaction with FliM and implications for organization of the switch complex. J. Bacteriol. 189 305-12 PubMed
  7. Marykwas, DL et al. (1996) Interacting components of the flagellar motor of Escherichia coli revealed by the two-hybrid system in yeast. J. Mol. Biol. 256 564-76 PubMed
  8. Marykwas, DL & Berg, HC (1996) A mutational analysis of the interaction between FliG and FliM, two components of the flagellar motor of Escherichia coli. J. Bacteriol. 178 1289-94 PubMed
  9. 9.0 9.1 9.2 9.3 9.4 9.5 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  10. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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