fis:Gene Product(s)

From EcoliWiki
Jump to: navigation, search

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Fis

Synonyms

global DNA-binding transcriptional dual regulator[1], B3261[2][1], Nbp[2][1], Fis[2][1], site-specific DNA inversion stimulation factor; DNA-binding protein; a trans activator for transcription[2][1] , ECK3248, JW3229, nbp, b3261

Product description

Fis transcriptional dual regulator[2][3]

Transcriptional activator for rRNA operons, bends DNA; interacts with RNAP; nucleoid-associated protein; dimeric[4]

EC number (for enzymes)


edit table

<protect></protect>

Notes

Function

[back to top]


<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005412

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00166

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002197

F

Seeded from EcoCyc (v14.0)

complete

GO:0003700

transcription factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020441

F

Seeded from EcoCyc (v14.0)

complete

GO:0006350

transcription

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc (v14.0)

complete

GO:0006355

regulation of transcription, DNA-dependent

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00166

P

Seeded from EcoCyc (v14.0)

complete

GO:0006355

regulation of transcription, DNA-dependent

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002197

P

Seeded from EcoCyc (v14.0)

complete

GO:0006355

regulation of transcription, DNA-dependent

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005412

P

Seeded from EcoCyc (v14.0)

complete

GO:0043565

sequence-specific DNA binding

PMID:10551881[5]

IDA: Inferred from Direct Assay

F

complete

GO:0006355

regulation of transcription, DNA-dependent

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020441

P

Seeded from EcoCyc (v14.0)

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rpsD

PMID:16606699[6]

Experiment(s):EBI-1145333

Protein

rplB

PMID:16606699[6]

Experiment(s):EBI-1145333

Protein

ycgE

PMID:16606699[6]

Experiment(s):EBI-1145333

Protein

rpsC

PMID:16606699[6]

Experiment(s):EBI-1145333

Protein

dnaK

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

hupA

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rplC

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rplD

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rplM

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rplS

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rplT

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rplV

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rplW

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rpmG

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rpoC

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rpsB

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rpsE

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rpsJ

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

rpsM

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

thiG

PMID:15690043[7]

Experiment(s):EBI-887368

Protein

thiG

PMID:19402753[8]

LCMS(ID Probability):99.0

Protein

Phage lambda Xis

PMID:1396573[9]

see Fig 4.

Protein

Phage lambda Int

PMID:1396573[9]

see Fig 4.

edit table

</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
edit table

<protect></protect>

Notes

Structure and Physical Properties

[back to top]


<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MFEQRVNSDV LTVSTVNSQD QVTQKPLRDS VKQALKNYFA QLNGQDVNDL YELVLAEVEQ
PLLDMVMQYT RGNQTRAALM MGINRGTLRK KLKKYGMN
Length

98

Mol. Wt

11.239 kDa

pI

9.8 (calculated)

Extinction coefficient

5,960 (calc based on 4 Y, 0 W, and 0 C residues)

edit table


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

54..95

PF02954 Bacterial regulatory protein, Fis family

PMID:19920124[10]

edit table

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=fis taxon=562,83333 </beststructure>

Models

View models at:

edit table
</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table

<protect></protect>

Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131149

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947697

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0010703

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0A6R3

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10317

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10317

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947697

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000311

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0313

Escherichia coli str. K-12 substr. MG1655

edit table

<protect></protect>

Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Azam, TA & Ishihama, A (1999) Twelve species of the nucleoid-associated protein from Escherichia coli. Sequence recognition specificity and DNA binding affinity. J. Biol. Chem. 274 33105-13 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  8. ↑ Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  9. ↑ 9.0 9.1 Numrych, TE et al. (1992) Characterization of the bacteriophage lambda excisionase (Xis) protein: the C-terminus is required for Xis-integrase cooperativity but not for DNA binding. EMBO J. 11 3797-806 PubMed
  10. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

[back to top]


Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=fis:Gene_Product(s)&oldid=1495056"