Plasmid F traA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

traA

Synonyms

traA, Fpla076

Product description

traA

this pilus subunit is processed to propilin and then N-acetylated by TraX; the subunits lying in the inner membrane are assembled to form the pilus, a long extracellular filament that is essential for transfer, contacts the recipient cell and retracts, bring the cells into close contact prior to conjugal DNA transfer

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0009418

pilus shaft

PMID:11849547[1]

IMP: Inferred from Mutant Phenotype

C

complete

GO:0044096

type IV pilus

PMID:11849547[1]

IMP: Inferred from Mutant Phenotype

C

complete

GO:0009291

unidirectional conjugation

PMID:4555413[2]

IGI: Inferred from Genetic Interaction

EcoliWiki:traA


P

complete

GO:0019062

virion attachment to host cell surface receptor

PMID:11849547[1]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0044096

type IV pilus

PMID:8444800[3]

IDA: Inferred from Direct Assay

C

complete

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Interactions <protect> See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

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Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence 
MNAVLSVQGA SAPVKKKSFF SKFTRLNMLR LARAVIPAAV LMMFFPQLAM AAGSSGQDLM
ASGNTTVKAT FGKDSSVVKW VVLAEVLVGA VMYMMTKNVK FLAGFAIISV FIAVGMAVVG L
Length

121

Mol. Wt

12.767 kDa

pI

11.0 (calculated)

Extinction coefficient

6,990 (calc based on 1 Y, 1 W, and 0 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References
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<motif_map/>

Structure
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Structures

<beststructure> gene=Plasmid_F_traA taxon=2465 </beststructure>

Models

View models at:

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</protect>

Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc

EcoCyc:

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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  1. ↑ 1.0 1.1 1.2 Manchak, J et al. (2002) Mutational analysis of F-pilin reveals domains for pilus assembly, phage infection and DNA transfer. Mol. Microbiol. 43 195-205 PubMed
  2. ↑ Willetts, N & Achtman, M (1972) Genetic analysis of transfer by the Escherichia coli sex factor F, using P1 transductional complementation. J. Bacteriol. 110 843-51 PubMed
  3. ↑ Moore, D et al. (1993) The Escherichia coli K-12 F plasmid gene traX is required for acetylation of F pilin. J. Bacteriol. 175 1375-83 PubMed

Categories

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