Phage lambda cII:On One Page

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Quickview | Gene | Product(s) | Expression| Evolution | References |

Quickview

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Standard Name

Phage lambda cII

Gene Synonym(s)

cII, lambdap59

Product Desc.

activator of Pre and Pi

Product Synonyms(s)

cII, lambdap59

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression
Regulation/Activity
Quick Links

porteco.png

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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Gene

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Nomenclature

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See Help:Gene_nomenclature for help with entering information in the Gene Nomenclature table.

Standard name

Phage lambda cII

Mnemonic
Synonyms

cII, lambdap59

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Notes

Location(s) and DNA Sequence

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<protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

BW2952

NC_012759: 4144117..4144254
gbrowse_img.php?coord=4144117..4144254&genome=BW2952&name=NC_012759&trackset=0&width=300&.png

NC_001416

NC_001416: 38360..38653
gbrowse_img.php?coord=38360..38653&genome=bacteriophage_lambda&name=NC_001416&trackset=0&width=300&.png

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Notes

Sequence Features

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See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes
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Notes

Alleles and Phenotypes

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See Help:Gene_alleles for how to enter or edit alleles and phenotypes in EcoliWiki.

Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments

can1

t →g on the + strand at bp 38364

 

 

 

 

 

 

cy3003

c →t on the + strand at bp 38370

 

 

 

 

 

 

cy42

a →t on the + strand at bp 38371

 

 

 

 

 

 

cy844

a →g on the + strand at bp 38376

 

 

 

 

 

 

cy3008

g →a on the + strand at bp 38379

 

 

 

 

 

 

cy3001

c →t on the + strand at bp 38380

 

 

 

 

 

 

cII2002

t →c on the + strand at bp 38430

 

 

 

 

 

 

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Notes

Genetic Interactions

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<protect>

Interactor Interaction Allele Score(s) Reference(s) Accessions Notes
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Notes

Genetic Resources

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See Help:Gene_resources for help entering information into the Genetic Resources table.

Resource Resource Type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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Name URL Comments
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Product(s)

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Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

cII

Synonyms

cII, lambdap59

Product description

activator of Pre and Pi

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

GO:0019044

maintenance of viral latency

PMID:9324241

IMP: Inferred from Mutant Phenotype

P

complete

GO:0019043

establishment of viral latency

PMID:12397182

IMP: Inferred from Mutant Phenotype

P

complete

GO:0045893

positive regulation of transcription, DNA-dependent

PMID:2931430

IDA: Inferred from Direct Assay

P

complete

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Interactions <protect> See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence 
MVRANKRNEA LRIESALLNK IAMLGTEKTA EAVGVDKSQI SRWKRDWIPK FSMLLAVLEW
GVVDDDMARL ARQVAAILTN KKRPAATERS EQIQMEF
Length

97

Mol. Wt

11.055 kDa

pI

10.1 (calculated)

Extinction coefficient

16,500 (calc based on 0 Y, 3 W, and 0 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=Phage_lambda_cII taxon=10710 </beststructure>

Models

View models at:

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</protect>

Structure figures

See Help:Jmol in EcoliWiki

Biological assembly of cII protein, PDB:1ZPQ
<jmol> <jmolApplet> <color>white</color> <uploadedFileContents >1ZPQ.pdb</uploadedFileContents> <name></name> <script> wireframe off; spacefill off; trace off; rotate ON; cartoon; color chain; </script> </jmolApplet> </jmol>
<jmol> <jmolCheckbox > <scriptWhenChecked > rotate on; </scriptWhenChecked > <scriptWhenUnchecked > rotate off; </scriptWhenUnchecked > <checked>true</checked> <text>rotate</text> </jmolCheckbox > <jmolButton><script>reset; </script><text>reset</text></jmolButton> </jmol>

See Help:Jmol in EcoliWiki

cII Protein/DNA complex: biological function. PDB:1ZS4l
<jmol> <jmolApplet> <color>white</color> <uploadedFileContents >1ZS4.pdb</uploadedFileContents> <name></name> <script> wireframe off; spacefill off; trace off; rotate ON; cartoon; color chain; </script> </jmolApplet> </jmol>
<jmol> <jmolCheckbox > <scriptWhenChecked > rotate on; </scriptWhenChecked > <scriptWhenUnchecked > rotate off; </scriptWhenUnchecked > <checked>true</checked> <text>rotate</text> </jmolCheckbox > <jmolButton><script>reset; </script><text>reset</text></jmolButton> </jmol>








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Notes

See Crystal structure of bacteriophage lambda cII and its DNA complex[1] , PDB 1ZPQ (protein alone), or PDB 1ZS4 (protein/DNA complex).

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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Name URL Comments
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Expression

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Overview

This is a placeholder for a summary statement on how expression of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.


Cellular Levels

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See Help:Cellular levels

Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)
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Notes

Transcription and Transcriptional Regulation

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<protect>

See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)

Phage lambda Pr - tr2

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Notes

This is a placeholder for a summary statement about how transcription of this gene is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Translation and Regulation of Translation

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<protect><gbrowseImage> name=NC_001416:38340..38380 source=bacteriophage_lambda type=CDS+DNA preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

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Notes

This is a placeholder for a summary statement about how translation of this gene product is regulated. You can help EcoliWiki by becoming a user and writing/editing this statement.

Turnover and Regulation of Turnover

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Notes

This is a placeholder for a summary statement about turnover of this gene product. You can help EcoliWiki by becoming a user and writing/editing this statement.

Experimental

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<protect> Mutations Affecting Expression See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference
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Expression Studies See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes
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Expression Resources See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes
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Notes

Accessions Related to Phage lambda cII Expression

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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Name URL Comments
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Evolution

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Homologs in Other Organisms

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See Help:Evolution_homologs for help entering or editing information in this section of EcoliWiki.

Organism Homologs (Statistics) Comments
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Do-It-Yourself Web Tools

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Notes

Families

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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Name URL Comments
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References

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  1. ↑ Jain, D et al. (2005) Crystal structure of bacteriophage lambda cII and its DNA complex. Mol. Cell 19 259-69 PubMed

Categories

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