Phage T4 60:On One Page

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References Suggestions

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Standard Name

60

Gene Synonym(s)
Product Desc.

topoisomerase II in T4 and related phages an insertion splits the large Topo II subunit in two parts (gp60 and gp39); a 50-bp segment is inserted in T4 gene 60 that forms an mRNA secondary structure that is translationally bypassed

Product Synonyms(s)
Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression
Regulation/Activity
Quick Links

porteco.png

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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References

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Gene

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Nomenclature Location(s) and DNA Sequence Sequence Features Alleles and Phenotypes Genetic Interactions Genetic Resources Accessions Links References Suggestions

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Nomenclature

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Standard name

60

Mnemonic
Synonyms


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Notes

Location(s) and DNA Sequence

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<protect> <protect> See Help:Gene_location for help entering information in the Gene Location and DNA sequence table.

Strain Map location Genome coordinates Genome browsers Sequence links

NC_000866: 1770..3490
<gbrowseImage> name=NC_000866:1770..3490 source= bacteriophage_T4 preset=GeneLocation </gbrowseImage>

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Notes

Sequence Features

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<protect> See Help:Gene_sequence_features for help in entering sequence features in EcoliWiki.

Feature Type Strain Genomic Location Evidence Reference Notes
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Notes

Alleles and Phenotypes

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Allele Nt change(s) AA change(s) Phenotype: Type Phenotype: Description Reference Availability Comments
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Notes

Genetic Interactions

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Interactor Interaction Allele Score(s) Reference(s) Accessions Notes
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Notes

Genetic Resources

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Resource Resource Type Source Notes/Reference
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Notes

Accessions in Other Databases

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<protect> See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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References

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Categories

Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

<protect> See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

gp60 topoisomerase II, large subunit, C-terminal region

Synonyms
Product description

topoisomerase II in T4 and related phages an insertion splits the large Topo II subunit in two parts (gp60 and gp39); a 50-bp segment is inserted in T4 gene 60 that forms an mRNA secondary structure that is translationally bypassed

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology <protect> See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
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Interactions <protect> See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

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Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties <protect> See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence 
MKFVKIDSSS VDMKKYKLQN NVRRSIKSSS MNYANVAIMT DADHDGLGSI YPSLLGFFSN
WPELFEQGRI RFVKTPVIIA QVGKKQEWFY TVAEYESAKD ALPKHSIRYI KGLGSLEKSE
YREMIQNPVY DVVKLPENWK ELFEMLMGDN ADLRKEWMSQ
Length

160

Mol. Wt

18.63 kDa

pI

9.0 (calculated)

Extinction coefficient

33,920 (calc based on 8 Y, 4 W, and 0 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References

Modification Site

160 - 160

Glutamine derivative (Probable)

UniProt:P23992


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<motif_map/>

Structure
<protect> See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=Phage_T4_60 taxon=10665 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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<protect> See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes
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Notes

Links

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References

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Categories

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Expression

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Overview Transcription Translation Turnover Experimental Links References Suggestions

Overview

Cellular Levels

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Molecule Organism or Strain Value Units Experimental Conditions Assay used Notes Reference(s)
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Notes

Transcription and Transcriptional Regulation

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See Help:Expression_transcription for help entering or editing information in this section of EcoliWiki.

Transcription unit(s)
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Notes

Translation and Regulation of Translation

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<protect><gbrowseImage> name=NC_000866:2782..2822 source= bacteriophage_T4 flip=1 type=Gene+DNA_+Protein preset=Nterminus </gbrowseImage> This picture shows the sequence around the N-terminus.

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Notes

Turnover and Regulation of Turnover

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Notes

Experimental

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<protect> Mutations Affecting Expression <protect> See Help:Expression_mutations for help entering or editing information in this section of EcoliWiki.

Allele Name Mutation Phenotype Reference
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Expression Studies <protect> See Help:Expression_studies for help entering or editing information in this section of EcoliWiki.

Type Reference Notes
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Expression Resources <protect> See Help:Expression_resources for help entering or editing information in this section of EcoliWiki.

Resource Name Resource Type Description Source Notes
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Notes

Accessions Related to Phage_T4_60 Expression

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Database Accession Notes
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Notes

Links

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References

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Categories

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Evolution

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Homologs Families Links References Suggestions

Homologs in Other Organisms

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Organism Homologs (Statistics) Comments
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Do-It-Yourself Web Tools

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Notes

Families

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Database Accession Notes
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Notes

Links

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References

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Categories

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