parC:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

ParC product

Synonyms

DNA topoisomerase IV, subunit A[1], B3019[2][1], ParC[2][1]

Product description

topoisomerase IV subunit A[2]; topoisomerase IV subunit A[3]; Component of dimer of topoisomerase IV subunit A[3]; dimer of topoisomerase IV subunit A[3]; Component of topoisomerase IV[3]; topoisomerase IV[3]

EC number (for enzymes)
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Notes

Function

Gene Ontology

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status

GO:0005737

cytoplasm

C

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0006261

DNA-dependent DNA replication

P

Seeded from EcoCyc 11.1[3].

required fields missing

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Interactions

Partner Type Partner Notes

Protein

Subunits of dimer of topoisomerase IV subunit A

could be indirect

Protein

Subunits of topoisomerase IV

could be indirect

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Notes

Localization

Compartment Description Evidence Notes

cytoplasm

From EcoCyc[3]

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Notes

Structure and Physical Properties

Physical Properties

Sequence

at EcoCyc

MSDMAERLAL HEFTENAYLN YSMYVIMDRA LPFIGDGLKP VQRRIVYAMS ELGLNASAKF
KKSARTVGDV LGKYHPHGDS ACYEAMVLMA QPFSYRYPLV DGQGNWGAPD DPKSFAAMRY
TESRLSKYSE LLLSELGQGT ADWVPNFDGT LQEPKMLPAR LPNILLNGTT GIAVGMATDI
PPHNLREVAQ AAIALIDQPK TTLDQLLDIV QGPDYPTEAE IITSRAEIRK IYENGRGSVR
MRAVWKKEDG AVVISALPHQ VSGARVLEQI AAQMRNKKLP MVDDLRDESD HENPTRLVIV
PRSNRVDMDQ VMNHLFATTD LEKSYRINLN MIGLDGRPAV KNLLEILSEW LVFRRDTVRR
RLNYRLEKVL KRLHILEGLL VAFLNIDEVI EIIRNEDEPK PALMSRFGLT ETQAEAILEL
KLRHLAKLEE MKIRGEQSEL EKERDQLQGI LASERKMNNL LKKELQADAQ AYGDDRRSPL
QEREEAKAMS EHDMLPSEPV TIVLSQMGWV RSAKGHDIDA PGLNYKAGDS FKAAVKGKSN
QPVVFVDSTG RSYAIDPITL PSARGQGEPL TGKLTLPPGA TVDHMLMESD DQKLLMASDA
GYGFVCTFND LVARNRAGKA LITLPENAHV MPPVVIEDAS DMLLAITQAG RMLMFPVSDL
PQLSKGKGNK IINIPSAEAA RGEDGLAQLY VLPPQSTLTI HVGKRKIKLR PEELQKVTGE
RGRRGTLMRG LQRIDRVEID SPRRASSGDS EE
Mol. Wt

83.83 kDa (calc) [2]

pI
Extinction coefficient

55810 - 56060 (calc based on 19 Y, 5 W, and 2 C residues)

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Domains/Motifs/Modification Sites

Type Residues Description Notes
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Structure

Structure Type Organism Accession Residues covered Notes

X-RAY DIFFRACTION

Escherichia coli

1ZVU Structure of the full-length E. coli ParC subunit

X-RAY DIFFRACTION

Escherichia coli

1ZVT Structure of the E. coli ParC C-terminal domain

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Notes

Gene Product Resources

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG10686-MONOMER

SwissModel (EcoliWiki Page)

SwissModel:P0AFI2

UniProt (EcoliWiki Page)

UniProt:P0AFI2

PFAM (EcoliWiki Page)

PFAM:PF00521

RefSeq (EcoliWiki Page)

RefSeq:NP_417491

ModBase (EcoliWiki Page)

ModBase:P0AFI2

PDB (EcoliWiki Page)

PDB:1ZVT

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Notes

Links

References

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  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 3.5 3.6 3.7 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7