flgE:Gene Product(s)

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

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Standard name

FlgE

Synonyms

flagellar hook protein[1], B1076[2][1], Fla[2][1], FlaK[2][1], FlgE[2][1]

Product description

flagellar hook protein FlgE[2][3];

Component of Flagellum[3]

Flagellar hook subunit protein[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0030694

flagellin-based flagellum basal body, rod

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011491

C

Seeded from EcoCyc [5]

complete

GO:0019861

flagellum

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR010930
SP_KW:KW-0282

C

Seeded from EcoCyc 12.5 [6]

complete

GO:0009288

bacterial-type flagellum

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

C

Seeded from EcoCyc 12.5 [6]

complete

GO:0005198

structural molecule activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

F

Seeded from EcoCyc [5]

complete

GO:0003774

motor activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

F

Seeded from EcoCyc [5]

complete

GO:0001539

ciliary or flagellar motility

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

P

Seeded from EcoCyc [5]

complete

GO:0005515

protein binding

PMID:16606699[7]

IPI: Inferred from Physical Interaction

UniProtKB:P18843

F

Seeded from EcoCyc [5]

complete

GO:0009296

flagellum biogenesis

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009425

bacterial-type flagellum basal body

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0142

C

Seeded from EcoCyc [5]

complete

GO:0042330

taxis

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0009424

bacterial-type flagellum hook

PMID:338588[8]

IMP: Inferred from Mutant Phenotype

C

complete

GO:0009424

bacterial-type flagellum hook

PMID:6374380[9]

IMP: Inferred from Mutant Phenotype

C

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of Flagellum

could be indirect

Protein

nadE

PMID:16606699[7]

Experiment(s):EBI-1138775
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Notes

Localization

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Compartment Description Evidence Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MAFSQAVSGL NAAATNLDVI GNNIANSATY GFKSGTASFA DMFAGSKVGL GVKVAGITQD
FTDGTTTNTG RGLDVAISQN GFFRLVDSNG SVFYSRNGQF KLDENRNLVN MQGLQLTGYP
ATGTPPTIQQ GANPTNISIP NTLMAAKTTT TASMQINLNS SDPLPTVTPF SASNADSYNK
KGSVTVFDSQ GNAHDMSVYF VKTGDNNWQV YTQDSSDPNS IAKTATTLEF NANGTLVDGA
MANNIATGAI NGAEPATFSL SFLNSMQQNT GANNIVATTQ NGYKPGDLVS YQINDDGTVV
GNYSNEQTQL LGQIVLANFA NNEGLASEGD NVWSATQSSG VALLGTAGTG NFGTLTNGAL
EASNVDLSKE LVNMIVAQRN YQSNAQTIKT QDQILNTLVN LR
Length

402

Mol. Wt

42.044 kDa

pI

4.3 (calculated)

Extinction coefficient

25,900 (calc based on 10 Y, 2 W, and C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References

Initiator Methionine

1

Removed (By similarity)

UniProt:P75937


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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=flgE taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:G361-MONOMER

SwissModel (EcoliWiki Page)

SwissModel:P75937

UniProt (EcoliWiki Page)

UniProt:P75937

PFAM (EcoliWiki Page)

PFAM:PF00460

RefSeq (EcoliWiki Page)

RefSeq:NP_415594


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ 6.0 6.1 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  7. ↑ 7.0 7.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  8. ↑ Komeda, Y et al. (1978) Identification of the structural gene for the hook subunit protein of Escherichia coli flagella. J. Bacteriol. 133 364-71 PubMed
  9. ↑ Komeda, Y et al. (1984) Synthesis of flagellin and hook subunit protein in flagellar mutants of Escherichia coli K12. Mol. Gen. Genet. 194 49-51 PubMed

Categories

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