flgE:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FlgE

Synonyms

flagellar hook protein[1], B1076[2][1], Fla[2][1], FlaK[2][1], FlgE[2][1] , ECK1061, flaK, JW1063, b1076

Product description

flagellar hook protein FlgE[2][3];

Component of Flagellum[3]

Flagellar hook subunit protein[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001539

ciliary or flagellar motility

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

P

Seeded from EcoCyc (v14.0)

complete

GO:0001539

ciliary or flagellar motility

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019776

P

Seeded from EcoCyc (v14.0)

complete

GO:0003774

motor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

F

Seeded from EcoCyc (v14.0)

complete

GO:0003774

motor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019776

F

Seeded from EcoCyc (v14.0)

complete

GO:0005198

structural molecule activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

F

Seeded from EcoCyc (v14.0)

complete

GO:0005198

structural molecule activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019776

F

Seeded from EcoCyc (v14.0)

complete

GO:0009288

bacterial-type flagellum

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

C

Seeded from EcoCyc (v14.0)

complete

GO:0009288

bacterial-type flagellum

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019776

C

Seeded from EcoCyc (v14.0)

complete

GO:0009288

bacterial-type flagellum

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0975

C

Seeded from EcoCyc (v14.0)

complete

GO:0009424

bacterial-type flagellum hook

PMID:338588[5]

IMP: Inferred from Mutant Phenotype

C

complete

GO:0009425

bacterial-type flagellum basal body

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0142

C

Seeded from EcoCyc (v14.0)

complete

GO:0009424

bacterial-type flagellum hook

PMID:6374380[6]

IMP: Inferred from Mutant Phenotype

C

complete

GO:0019861

flagellum

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010930

C

Seeded from EcoCyc (v14.0)

complete

GO:0030694

bacterial-type flagellum basal body, rod

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011491

C

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of Flagellum

could be indirect

Protein

nadE

PMID:16606699[7]

Experiment(s):EBI-1138775

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MAFSQAVSGL NAAATNLDVI GNNIANSATY GFKSGTASFA DMFAGSKVGL GVKVAGITQD
FTDGTTTNTG RGLDVAISQN GFFRLVDSNG SVFYSRNGQF KLDENRNLVN MQGLQLTGYP
ATGTPPTIQQ GANPTNISIP NTLMAAKTTT TASMQINLNS SDPLPTVTPF SASNADSYNK
KGSVTVFDSQ GNAHDMSVYF VKTGDNNWQV YTQDSSDPNS IAKTATTLEF NANGTLVDGA
MANNIATGAI NGAEPATFSL SFLNSMQQNT GANNIVATTQ NGYKPGDLVS YQINDDGTVV
GNYSNEQTQL LGQIVLANFA NNEGLASEGD NVWSATQSSG VALLGTAGTG NFGTLTNGAL
EASNVDLSKE LVNMIVAQRN YQSNAQTIKT QDQILNTLVN LR
Length

402

Mol. Wt

42.044 kDa

pI

4.3 (calculated)

Extinction coefficient

25,900 (calc based on 10 Y, 2 W, and 0 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed (By similarity)

UniProt:P75937

Domain

3..33

PF00460 Flagella basal body rod protein

PMID:19920124[8]

Domain

363..401

PF06429 Domain of unknown function (DUF1078)

PMID:19920124[8]

Domain

170..283

PF07559 Flagellar basal body protein FlaE

PMID:19920124[8]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=flgE taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129039

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945636

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003647

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P75937

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G361

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG14269

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945636

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002683

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB4017

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Komeda, Y et al. (1978) Identification of the structural gene for the hook subunit protein of Escherichia coli flagella. J. Bacteriol. 133 364-71 PubMed
  6. Komeda, Y et al. (1984) Synthesis of flagellin and hook subunit protein in flagellar mutants of Escherichia coli K12. Mol. Gen. Genet. 194 49-51 PubMed
  7. Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  8. 8.0 8.1 8.2 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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