add:Gene Product(s): Difference between revisions

From EcoliWiki
Jump to navigation Jump to search
← Older editNewer edit →
imported>Wikientrybot
Move help links into the <above> tag inside templates.
Table edited by M gehrig2000 via TableEdit
Line 242: Line 242:
|
|
UniProtKB:P56658
UniProtKB:P56658
|
F
|
|
complete
|-
|
|
GO:0004000
|
adenosine deaminase activity
|
PMID:4874315
|
IDA: Inferred from Direct Assay
|
|
|
F
F

Revision as of 17:53, 17 February 2009

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Add

Synonyms

adenosine deaminase[1], B1623[2][1], Add[2][1]

Product description

ADENODEAMIN[2][3]

EC number (for enzymes)
edit table


Notes

Function

[back to top]


Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0016787

hydrolase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0009168

purine ribonucleoside monophosphate biosynthetic process

GO_REF:0000002
GO_REF:0000002
GO_REF:0000002
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR001365
InterPro:IPR006330
InterPro:IPR006650
HAMAP:MF_00540

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0009117

nucleotide metabolic process

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0546

P

Seeded from EcoCyc 12.5 [4]

complete

GO:0004000

adenosine deaminase activity

GO_REF:0000002
GO_REF:0000003
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR006330
EC:3.5.4.4
HAMAP:MF_00540

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0019239

deaminase activity

GO_REF:0000002
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001365
InterPro:IPR006650

F

Seeded from EcoCyc 12.5 [4]

complete

GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

required fields missing

GO:0015949

nucleobase, nucleoside and nucleotide interconversion

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0005488

binding

PMID:3486673[5]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P56658

F

CHEBI:27834 (Deoxycoformycin mechanistically inhibits Add).

complete

GO:0004000

adenosine deaminase activity

PMID:5335916[6]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P56658

F

complete

GO:0004000

adenosine deaminase activity

PMID:4874315[7]

IDA: Inferred from Direct Assay

F

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rpsM

PMID:16606699[8]

Experiment(s):EBI-1140315

Protein

arpA

PMID:16606699[8]

Experiment(s):EBI-1140315

Protein

rplT

PMID:16606699[8]

Experiment(s):EBI-1140315

Protein

insC1

PMID:16606699[8]

Experiment(s):EBI-1140315

Protein

ligA

PMID:16606699[8]

Experiment(s):EBI-1140315

Protein

gcd

PMID:16606699[8]

Experiment(s):EBI-1140315

Small Molecule

CHEBI:27834 (Deoxycoformycin)

Inhibitor of Add activity


edit table


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Notes
edit table


Notes

Structure and Physical Properties

[back to top]


Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MIDTTLPLTD IHRHLDGNIR PQTILELGRQ YNISLPAQSL ETLIPHVQVI ANEPDLVSFL
TKLDWGVKVL ASLDACRRVA FENIEDAARH GLHYVELRFS PGYMAMAHQL PVAGVVEAVI
DGVREGCRTF GVQAKLIGIM SRTFGEAACQ QELEAFLAHR DQITALDLAG DELGFPGSLF
LSHFNRARDA GWHITVHAGE AAGPESIWQA IRELGAERIG HGVKAIEDRA LMDFLAEQQI
GIESCLTSNI QTSTVAELAA HPLKTFLEHG IRASINTDDP GVQGVDIIHE YTVAAPAAGL
SREQIRQAQI NGLEMAFLSA EEKRALREKV AAK
Mol. Wt

36.4 kDa (calc) [2]

pI

5.63[2]

Extinction coefficient

22460 - 22960 (calc based on 4 Y, 3 W, and 4 C residues)

edit table


Domains/Motifs/Modification Sites See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes
edit table


Structure See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure>add 562</beststructure>

Models

View models at:

edit table


Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table


Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:ADENODEAMIN-MONOMER

UniProt (EcoliWiki Page)

UniProt:P22333

PFAM (EcoliWiki Page)

PFAM:PF00962

RefSeq (EcoliWiki Page)

RefSeq:NP_416140

ModBase (EcoliWiki Page)

ModBase:P22333


edit table


Notes

Links

[back to top]


Name URL Comments
edit table



References

[back to top]


  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ 4.0 4.1 4.2 4.3 4.4 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  5. ↑ Frick, L et al. (1986) Transition-state stabilization by adenosine deaminase: structural studies of its inhibitory complex with deoxycoformycin. Biochemistry 25 1616-21 PubMed
  6. ↑ Wolfenden, R et al. (1967) Substrate binding by adenosine deaminase. Specificity, pH dependence, and competition by mercurials. J. Biol. Chem. 242 977-83 PubMed
  7. ↑ Remy, CN & Love, SH (1968) Induction of adenosine deaminase in Escherichia coli. J. Bacteriol. 96 76-85 PubMed
  8. ↑ 8.0 8.1 8.2 8.3 8.4 8.5 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed


Categories

[back to top]


Retrieved from "https://ecoliwiki.org/colipedia/index.php?title=add:Gene_Product(s)&oldid=732480"