lpxD:Gene Product(s): Difference between revisions

Standard name	LpxD
Synonyms	UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase^[1], B0179^[2]^[1], OmsA^[2]^[1], Ssc^[2]^[1], OsmA^[2]^[1], FirA^[2]^[1], LpxD^[2]^[1]
Product description	UDP-3-O-(3-hydroxymyristoyl)-glucosamine N-acyltransferase
EC number (for enzymes)	2.3.1.-^[1] LPS biosynthesis
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Notes

Function

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Gene Ontology
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Qualifier	GO ID	GO term name	Reference(s)	Evidence Code	with/from	Aspect	Notes	Status
	GO:0008610	lipid biosynthetic process	GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0444	P	Seeded from EcoCyc 12.5 ^[3]	complete
	GO:0008415	acyltransferase activity	GO_REF:0000002 GO_REF:0000004	IEA: Inferred from Electronic Annotation	InterPro:IPR001451 SP_KW:KW-0012	F	Seeded from EcoCyc 12.5 ^[3]	complete
	GO:0005737	cytoplasm				C	Seeded from Riley et al 2006 ^[1].	required fields missing
	GO:0016410	N-acyltransferase activity	PMID:3288280^[4]	IDA: Inferred from Direct Assay		F		complete
	GO:0009245	lipid A biosynthetic process	PMID:8366125^[5]	IMP: Inferred from Mutant Phenotype		P		complete
	GO:0016410	N-acyltransferase activity	PMID:8366125^[5]	IDA: Inferred from Direct Assay		F		complete
	GO:0009245	lipid A biosynthetic process	GO_REF:0000002 GO_REF:0000004 GO_REF:0000020	IEA: Inferred from Electronic Annotation	InterPro:IPR007691 SP_KW:KW-0441 HAMAP:MF_00523	P	Seeded from EcoCyc 12.5 ^[3]	complete
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Interactions

Partner Type	Partner	Notes
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Notes

Localization

Compartment	Description	Evidence	Notes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence	at EcoCyc MPSIRLADLA QQLDAELHGD GDIVITGVAS MQSAQTGHIT FMVNPKYREH LGLCQASAVV MTQDDLPFAK SAALVVKNPY LTYARMAQIL DTTPQPAQNI APSAVIDATA KLGNNVSIGA NAVIESGVEL GDNVIIGAGC FVGKNSKIGA GSRLWANVTI YHEIQIGQNC LIQSGTVVGA DGFGYANDRG NWVKIPQIGR VIIGDRVEIG ACTTIDRGAL DDTIIGNGVI IDNQCQIAHN VVIGDNTAVA GGVIMAGSLK IGRYCMIGGA SVINGHMEIC DKVTVTGMGM VMRPITEPGV YSSGIPLQPN KVWRKTAALV MNIDDMSKRL KSLERKVNQQ D
Mol. Wt	36.04 kDa (calc) ^[2]
pI	6.48^[2]
Extinction coefficient	26930 - 27805 (calc based on 7 Y, 3 W, and 7 C residues)
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Domains/Motifs/Modification Sites

Type	Residues	Description	Notes
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Structure

Structures

Models

View models at:

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Notes

Gene Product Resources

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Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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Database	Accession	Notes
EcoCyc (EcoliWiki Page)	EcoCyc:UDPHYDROXYMYRGLUCOSAMNACETYLTRANS-MONO
UniProt (EcoliWiki Page)	UniProt:P21645
PFAM (EcoliWiki Page)	PFAM:PF04613
RefSeq (EcoliWiki Page)	RefSeq:NP_414721
ModBase (EcoliWiki Page)	ModBase:P21645
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Notes

Links

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Name	URL	Comments
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References

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↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 ^1.7 ^1.8 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 ^2.7 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 ^3.2 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ Anderson, MS et al. (1988) Biosynthesis of lipid A in Escherichia coli: identification of UDP-3-O-[(R)-3-hydroxymyristoyl]-alpha-D-glucosamine as a precursor of UDP-N2,O3-bis[(R)-3-hydroxymyristoyl]-alpha-D-glucosamine. Biochemistry 27 1908-17 PubMed
↑ ^5.0 ^5.1 Kelly, TM et al. (1993) The firA gene of Escherichia coli encodes UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase. The third step of endotoxin biosynthesis. J. Biol. Chem. 268 19866-74 PubMed

@@ Line 78: / Line 78: @@
 |- {{table_heading_style}}
 !|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
+|-
+|
+|
+[[Category:GO:0008610_!_lipid_biosynthetic_process]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008610_!_lipid_biosynthetic_process GO:0008610]
+|
+lipid biosynthetic process
+|
+[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
+|
+IEA: Inferred from Electronic Annotation
+|
+[http://www.uniprot.org/keywords/KW-0444 SP_KW:KW-0444]
+|
+P
+|
+Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+|
+complete
 |-
 |
@@ Line 177: / Line 196: @@
 |
-[[Category:GO:0008610_!_lipid_biosynthetic_process]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0008610_!_lipid_biosynthetic_process GO:0008610]
+[[Category:GO:0009245_!_lipid_A_biosynthetic_process]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0009245_!_lipid_A_biosynthetic_process GO:0009245]
 |
-lipid biosynthetic process
+lipid A biosynthetic process
 |
-[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]
+[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000002 GO_REF:0000002]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000004 GO_REF:0000004]<br />[http://www.geneontology.org/cgi-bin/references.cgi#GO_REF:0000020 GO_REF:0000020]
 |
 IEA: Inferred from Electronic Annotation
 |
-[http://www.uniprot.org/keywords/KW-0444 SP_KW:KW-0444]
+[http://www.ebi.ac.uk/interpro/DisplayIproEntry?ac=IPR007691 InterPro:IPR007691]<br />[http://www.uniprot.org/keywords/KW-0441 SP_KW:KW-0441]<br />HAMAP:MF_00523
 |
 P

lpxD:Gene Product(s): Difference between revisions

Revision as of 04:00, 18 November 2008

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

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lpxD:Gene Product(s): Difference between revisions

Revision as of 04:00, 18 November 2008

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

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