Essential genes: Difference between revisions
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acpH:Gene | acpH:Gene | ||
adrA:Gene | adrA:Gene | ||
araA:Gene | |||
araB:Gene | |||
araD:Gene | |||
arpB_2:Gene | arpB_2:Gene | ||
degS:Gene | degS:Gene | ||
Revision as of 12:01, 22 August 2008
Introduction and caveats
This page displays a list of E. coli genes that may be essential. The list is generated by removing all genes where Keio deletions have been isolated, and all ins genes that are from insertion elements. The list was then manually curated to remove obvious pseudogenes. Community curation is needed to improve the quality of this list. Genes can be removed from the list by editing the list of gene pages in the wikitext of this page
<essentialGenes> nonessential gene 1:Gene nonessential gene 2:Gene etc. </essentialGenes>
tRNA genes that can be mutated to nonsense suppressors are marked as nonessential. Note that in many cases these are redundant and not all copies of a tRNA isoacceptor can be simultaneously deleted. Similarly, although ribosomal RNA genes are not on this list, at least one of each rRNA is needed for viability.
The list (Edit this)
<essentialGenes> List nonessential gene pages here accD:Gene acpH:Gene adrA:Gene araA:Gene araB:Gene araD:Gene arpB_2:Gene degS:Gene dpiA:Gene dpiB:Gene dsbD:Gene efeU_2:Gene entD:Gene etk:Gene eutD:Gene eutK:Gene eutM:Gene eutR:Gene eutS:Gene fldA:Gene folA:Gene folD:Gene ftnA:Gene ftnB:Gene ftsN:Gene ftsX:Gene gapC_1:Gene gatA:Gene gatR_2:Gene glcA:Gene glnU:Gene glnV:Gene glnX:Gene gpsA:Gene gsp:Gene hflB:Gene ilvG_2:Gene istR-1:Gene istR-2:Gene intZ:Gene kup:Gene lacZ:Gene leuX:Gene lolA:Gene lomR_2:Gene lysT:Gene lyx:Gene mazE:Gene mazF:Gene micF:Gene mraY:Gene mreD:Gene molR_3:Gene mug:Gene murA:Gene murB:Gene murF:Gene nadD:Gene oriC:Gene orn:Gene pgmB:Gene pinE:Gene pptA:Gene ptrA:Gene purB:Gene qmcA:Gene queC:Gene queF:Gene raiA:Gene ravA:Gene rcnA:Gene rimN:Gene rlmG:Gene rlmL:Gene rluE:Gene rluF:Gene rnlA:Gene rpsG:Gene rplP:Gene rplV:Gene rpsF:Gene rpsI:Gene rpsM:Gene rpsO:Gene rpsQ:Gene rpsT:Gene rrfA:Gene rrfB:Gene rrfC:Gene rrfD:Gene rrfE:Gene rrfF:Gene rrfG:Gene rrfH:Gene rrsA:Gene rrsB:Gene rrsC:Gene rrsD:Gene rrsE:Gene rrsF:Gene rrsG:Gene rrsH:Gene rrlA:Gene rrlB:Gene rrlC:Gene rrlD:Gene rrlE:Gene rrlF:Gene rrlG:Gene rrlH:Gene rsmE:Gene rsmF:Gene rutA:Gene serU:Gene serV:Gene ssrA:Gene trpH:Gene tusB:Gene tusC:Gene tusD:Gene tusE:Gene tyrT:Gene ubiD:Gene uspB:Gene wbbL_1:Gene xni:Gene yabQ:Gene yadR:Gene ybfK:Gene ycgH_2:Gene ychE_2:Gene ychG_1:Gene ychO:Gene ydbA_2:Gene ydiL:Gene yedN_1:Gene yedS_3:Gene yeeL_1:Gene yejM:Gene yfaS_1:Gene yffL:Gene yffN:Gene yffP:Gene yffQ:Gene ygiA:Gene ygiD:Gene yhbV:Gene yi82_1:Gene ylbE_2:Gene yibJ:Gene yigP:Gene yjgX_1:Gene yjjL:Gene yncK_2:Gene ypjK:Gene yraL:Gene yrbB:Gene yrfF:Gene ysaA:Gene </essentialGenes>
Evidence
Add evidence for nonessentiality here:
| Gene | Reference(s) | Comments |
|---|---|---|
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micF |
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rpsF, rpsI, rpsM, rpsO, rpsQ, and rpsT |
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accD, degS, dpiA, dpiB, entD, etk,eutD, eutK, eutM, eutR, eutS, fldA, folD, ftnA, ftnB, ftsN, ftsX, gatA, glcA, gpsA, gsp, hflB, intZ, kup, lolA, lyx, mraY, mreD, mug, murA, murB, murF, nadD, pgmB, pptA, ptrA, purB, qmcA, queC, queF, raiA, ravA, rimN, rlmG, rluE, rluF, rplP, rplV, rpsG, rsmE, rsmF, rutA, trpH, ubiD, uspB, xni, yabQ, yadR, ybfK, ychO, ydiL, yejM, yffL yffN, yffP, yffQ, ygiA, ygiD, yhbV, yibJ, yigP, yjjL, ypjK, yraL, yrbB, yrfF, ysaA |
accD listed as N* | |
| edit table |
Add evidence for essentiality here:
| Gene | Reference(s) | Comments |
|---|---|---|
|
nusA |
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nusE |
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nusG |
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| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ Krishnan, BR & Berg, DE (1993) Viability of folA-null derivatives of wild-type (thyA+) Escherichia coli K-12. J. Bacteriol. 175 909-11 PubMed
- ↑ Chen, S et al. (2004) MicC, a second small-RNA regulator of Omp protein expression in Escherichia coli. J. Bacteriol. 186 6689-97 PubMed
- ↑ Liu, MY et al. (1995) The product of the pleiotropic Escherichia coli gene csrA modulates glycogen biosynthesis via effects on mRNA stability. J. Bacteriol. 177 2663-72 PubMed
- ↑ Gerdes, SY et al. (2003) Experimental determination and system level analysis of essential genes in Escherichia coli MG1655. J. Bacteriol. 185 5673-84 PubMed
- ↑ 5.0 5.1 5.2 Bubunenko, M et al. (2007) Essentiality of ribosomal and transcription antitermination proteins analyzed by systematic gene replacement in Escherichia coli. J. Bacteriol. 189 2844-53 PubMed