nadC:Gene Product(s): Difference between revisions

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[[Category:GO:0004514_!_nicotinate-nucleotide_diphosphorylase_(carboxylating)_activity]][[:Category:GO:0004514_!_nicotinate-nucleotide_diphosphorylase_(carboxylating)_activity|GO:0004514]]
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nicotinate-nucleotide diphosphorylase (carboxylating) activity
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[[PMID:203571]]<ref name=PMID:203571/>
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IMP: Inferred from Mutant Phenotype
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F
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QAPRTase activity displayed in Table 4.
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complete
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Revision as of 17:06, 4 April 2008

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Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Structure Resources Accessions Links References Suggestions

Nomenclature

Standard name

NadC product

Synonyms

quinolinate phosphoribosyltransferase product[1], B0109 product[2][1], Nic product[2][1], NadC product[2][1], nicotinate-nucleotide pyrophosphorylase (carboxylating) product[2][1], QAPRTase product[2][1], nicotinate-nucleotide:pyrophosphate phospho-α-D-ribosyltransferase (carboxylating) product[2][1]

Product description

quinolinate phosphoribosyltransferase (decarboxylating) monomer[2][3];

Component of ; quinolinate phosphoribosyltransferase (decarboxylating)[2][3]

EC number (for enzymes)
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Notes

Function

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Gene Ontology

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

required fields missing

GO:0009435

NAD biosynthetic process

P

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0004514

nicotinate-nucleotide diphosphorylase (carboxylating) activity

ISS: Inferred from Sequence or Structural Similarity

P30012 from

F

Activity for S. typhimurium NadC shown in [4]

required field missing

GO:0004514

nicotinate-nucleotide diphosphorylase (carboxylating) activity

PMID:203571[5]

IMP: Inferred from Mutant Phenotype

F

QAPRTase activity displayed in Table 4.

complete

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Interactions

Partner Type Partner Notes

Protein

Subunits of quinolinate phosphoribosyltransferase (decarboxylating)

could be indirect

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Notes

Localization

Compartment Description Evidence Notes
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Notes

Structure and Physical Properties

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Physical Properties

Sequence

at EcoCyc

MPPRRYNPDT RRDELLERIN LDIPGAVAQA LREDLGGTVD ANNDITAKLL PENSRSHATV
ITRENGVFCG KRWVEEVFIQ LAGDDVTIIW HVDDGDVINA NQSLFELEGP SRVLLTGERT
ALNFVQTLSG VASKVRHYVE LLEGTNTQLL DTRKTLPGLR SALKYAVLCG GGANHRLGLS
DAFLIKENHI IASGSVRQAV EKASWLHPDA PVEVEVENLE ELDEALKAGA DIIMLDNFET
EQMREAVKRT NGKALLEVSG NVTDKTLREF AETGVDFISV GALTKHVQAL DLSMRFR
Mol. Wt

32.76 kDa (calc) [2]

pI

4.86[2]

Extinction coefficient

20970 - 21220 (calc based on 3 Y, 3 W, and 2 C residues)

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Domains/Motifs/Modification Sites

Type Residues Description Notes
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Structure

Structure Type Organism Accession Residues covered Notes
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Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:QUINOPRIBOTRANS-MONOMER

SwissModel (EcoliWiki Page)

SwissModel:P30011

UniProt (EcoliWiki Page)

UniProt:P30011

PFAM (EcoliWiki Page)

PFAM:PF02749

RefSeq (EcoliWiki Page)

RefSeq:NP_414651

ModBase (EcoliWiki Page)

ModBase:P30011

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Notes

Links

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Name URL Comments
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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ Hughes, KT et al. (1993) The Salmonella typhimurium nadC gene: sequence determination by use of Mud-P22 and purification of quinolinate phosphoribosyltransferase. J. Bacteriol. 175 479-86 PubMed
  5. ↑ Foster, JW & Moat, AG (1978) Mapping and characterization of the nad genes in Salmonella typhimurium LT-2. J. Bacteriol. 133 775-9 PubMed


Categories

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