setB:Gene Product(s): Difference between revisions

Standard name	SetB
Synonyms	lactose/glucose efflux system^[1], B2170^[2]^[1], YeiO^[2]^[1], SetB^[2]^[1] , ECK2163, JW2157, yeiO, b2170
Product description	SetB MFS transporter^[2]^[3] Glucose and lactose efflux transporter^[4]
EC number (for enzymes)
edit table

Notes

Function

[back to top]

Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0005886	plasma membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0997	C	Seeded from EcoCyc (v14.0)	complete
	GO:0005886	plasma membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-1003	C	Seeded from EcoCyc (v14.0)	complete
	GO:0015542	sugar efflux transmembrane transporter activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004750	F	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0472	C	Seeded from EcoCyc (v14.0)	complete
	GO:0007059	chromosome segregation	PMID:14617174^[5]	IMP: Inferred from Mutant Phenotype		P		complete
	GO:0016021	integral to membrane	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004750	C	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	PMID:14617174^[5]	IDA: Inferred from Direct Assay		C		complete
	GO:0016021	integral to membrane	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0812	C	Seeded from EcoCyc (v14.0)	complete
	GO:0015767	lactose transport	PMID:10438463^[6]	IDA: Inferred from Direct Assay		P		complete
	GO:0015542	sugar efflux transmembrane transporter activity	PMID:10438463^[6]	IDA: Inferred from Direct Assay		F		complete
	GO:0016021	integral to membrane	GO_REF:0000023	IEA: Inferred from Electronic Annotation	SP_SL:SL-9909	C	Seeded from EcoCyc (v14.0)	complete
	GO:0015758	glucose transport	PMID:10438463^[6]	IDA: Inferred from Direct Assay		P		complete
	GO:0055085	transmembrane transport	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR011701	P	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	PMID:10438463^[6]	IDA: Inferred from Direct Assay		C		complete
edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
Protein	MreB		PMID:14617174^[5]
edit table

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source	Notes
plasma membrane	C-terminus localized in the cytoplasm with 12 predicted transmembrane domains	Daley et al. (2005) ^[7]
edit table

Notes

Structure and Physical Properties

[back to top]

Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	at EcoCyc MHNSPAVSSA KSFDLTSTAF LIVAFLTGIA GALQTPTLSI FLTDEVHARP AMVGFFFTGS AVIGILVSQF LAGRSDKRGD RKSLIVFCCL LGVLACTLFA WNRNYFVLLF VGVFLSSFGS TANPQMFALA REHADKTGRE AVMFSSFLRA QVSLAWVIGP PLAYALAMGF SFTVMYLSAA VAFIVCGVMV WLFLPSMRKE LPLATGTIEA PRRNRRDTLL LFVICTLMWG SNSLYIINMP LFIINELHLP EKLAGVMMGT AAGLEIPTML IAGYFAKRLG KRFLMRVAAV GGVCFYAGML MAHSPVILLG LQLLNAIFIG ILGGIGMLYF QDLMPGQAGS ATTLYTNTSR VGWIIAGSVA GIVAEIWNYH AVFWFAMVMI IATLFCLLRI KDV
Length	393
Mol. Wt	42.747 kDa
pI	10.1 (calculated)
Extinction coefficient	51,910 - 52,785 (calc based on 9 Y, 7 W, and 7 C residues)
edit table

Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	Notes	References
Domain	20..357	PF07690 Major Facilitator Superfamily		PMID:19920124^[8]
edit table

<motif_map/>

Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=setB taxon=562,83333 </beststructure>

Models

View models at:

edit table

Structure figures

Notes

Gene Product Resources

[back to top]

See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
edit table

Notes

Accessions in Other Databases

[back to top]

See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
NCBI (Protein) (EcoliWiki Page)	GI:16130108	Escherichia coli str. K-12 substr. MG1655
NCBI (Protein) (EcoliWiki Page)	GeneID:946673	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0007184	Escherichia coli str. K-12 substr. MG1655
UniProt (EcoliWiki Page)	UniProtKB/Swiss-Prot:P33026	Escherichia coli str. K-12 substr. MG1655
EcoCyc	EcoCyc:EG12034	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG12034	Escherichia coli str. K-12 substr. MG1655
NCBI (Gene) (EcoliWiki Page)	GeneID:946673	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120001951	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB1969	Escherichia coli str. K-12 substr. MG1655
edit table

Notes

Links

[back to top]

Name	URL	Comments
edit table

References

[back to top]

See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 ^5.2 Espeli, O et al. (2003) SetB: an integral membrane protein that affects chromosome segregation in Escherichia coli. Mol. Microbiol. 50 495-509 PubMed
↑ ^6.0 ^6.1 ^6.2 ^6.3 Liu, JY et al. (1999) Functional and biochemical characterization of Escherichia coli sugar efflux transporters. J. Biol. Chem. 274 22977-84 PubMed
↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

@@ Line 450: / Line 450: @@
 !align=left {{table heading style}} |Mol. Wt
 ||
-Da
+.747 kDa
 |-
 !align=left {{table heading style}} |pI
 ||
 .1 (calculated)
 |-
 !align=left {{table heading style}} |Extinction coefficient
 ||
-(calc based on 0 Y, 0 W, and 0 C residues)
+,910 - 52,785 (calc based on 9 Y, 7 W, and 7 C residues)
 |- class="tableEdit_footer"

setB:Gene Product(s): Difference between revisions

Revision as of 20:47, 17 February 2015

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

setB:Gene Product(s): Difference between revisions

Revision as of 20:47, 17 February 2015

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

Search