setB:Gene Product(s)
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
SetB |
|---|---|
| Synonyms |
lactose/glucose efflux system[1], B2170[2][1], YeiO[2][1], SetB[2][1] , ECK2163, JW2157, yeiO, b2170 |
| Product description |
Glucose and lactose efflux transporter[4] |
| EC number (for enzymes) |
|
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005886 |
plasma membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005886 |
plasma membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016020 |
membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0007059 |
chromosome segregation |
IMP: Inferred from Mutant Phenotype |
P |
complete | ||||
| GO:0016021 |
integral to membrane |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016020 |
membrane |
IDA: Inferred from Direct Assay |
C |
complete | ||||
| GO:0016021 |
integral to membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0015767 |
lactose transport |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0005351 |
carbohydrate:proton symporter activity |
IDA: Inferred from Direct Assay |
F |
complete | ||||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-9909 |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0015758 |
glucose transport |
IDA: Inferred from Direct Assay |
P |
complete | ||||
| GO:0055085 |
transmembrane transport |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016020 |
membrane |
IDA: Inferred from Direct Assay |
C |
complete | ||||
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
MreB |
| ||
| edit table |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
|
plasma membrane |
C-terminus localized in the cytoplasm with 12 predicted transmembrane domains |
Daley et al. (2005) [7] |
| |
| edit table |
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MHNSPAVSSA KSFDLTSTAF LIVAFLTGIA GALQTPTLSI FLTDEVHARP AMVGFFFTGS AVIGILVSQF LAGRSDKRGD RKSLIVFCCL LGVLACTLFA WNRNYFVLLF VGVFLSSFGS TANPQMFALA REHADKTGRE AVMFSSFLRA QVSLAWVIGP PLAYALAMGF SFTVMYLSAA VAFIVCGVMV WLFLPSMRKE LPLATGTIEA PRRNRRDTLL LFVICTLMWG SNSLYIINMP LFIINELHLP EKLAGVMMGT AAGLEIPTML IAGYFAKRLG KRFLMRVAAV GGVCFYAGML MAHSPVILLG LQLLNAIFIG ILGGIGMLYF QDLMPGQAGS ATTLYTNTSR VGWIIAGSVA GIVAEIWNYH AVFWFAMVMI IATLFCLLRI KDV |
| Length |
393 |
| Mol. Wt |
42.747 kDa |
| pI |
10.1 (calculated) |
| Extinction coefficient |
51,910 - 52,785 (calc based on 9 Y, 7 W, and 7 C residues) |
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Domains/Motifs/Modification Sites
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See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
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Structure
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Structure figures<protect> | ||||||
Notes
Gene Product Resources
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| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 5.2 Espeli, O et al. (2003) SetB: an integral membrane protein that affects chromosome segregation in Escherichia coli. Mol. Microbiol. 50 495-509 PubMed
- ↑ 6.0 6.1 6.2 6.3 Liu, JY et al. (1999) Functional and biochemical characterization of Escherichia coli sugar efflux transporters. J. Biol. Chem. 274 22977-84 PubMed
- ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
- ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
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