msbA:Gene Product(s): Difference between revisions

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MsbA  
MsbA  
|-
!align=left {{table heading style}} |Synonyms
||
fused lipid transporter subunits of ABC superfamily: membrane component<ref name='LIB:Riley_2006'/>, ATP-binding component<ref name='LIB:Riley_2006'/>, B0914<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
fused lipid transporter subunits of ABC superfamily: membrane component<ref name='LIB:Riley_2006'/>, ATP-binding component<ref name='LIB:Riley_2006'/>, B0914<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
|-
!align=left {{table heading style}} |Product description
||
ATP-binding transport protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
ATP-binding transport protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase<ref name='LIB:EcoGene'/>
Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase<ref name='LIB:EcoGene'/>
|-
!align=left {{table heading style}} |EC number (for enzymes)
||




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<protect><!--Nomenclature_notes--></protect>
===Notes===




==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big><br /><!--box uid=421aa90e079fa326b6494f812ad13e79.21674.B46aa4b479d593-->
<!--
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{|  id="B46aa4b479d593"  class=" tableEdit GO_table_product dataTable" 
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|


|
GO:0005515
|
protein binding
|
PMID:18344567
|
IDA: Inferred from Direct Assay
|


|
C
|


|
complete
|-
|


|
GO:0034040
|
lipid-transporting ATPase activity
|
PMID:18344567
|
IDA: Inferred from Direct Assay
|


|
F
|


|
complete
|-
|


|
GO:0008289
|
lipid binding
|
PMID:18344567
|
IDA: Inferred from Direct Assay
|


|
F
|


|
complete
|-
|


|
GO:0008144
|
drug binding
|
PMID:18344567
|
IDA: Inferred from Direct Assay
|


|
F
|


|
complete
|-
|


|
GO:0005319
|
lipid transporter activity
|
GOA:hamap<br />GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_01703
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


 
|
 
GO:0005524
 
|
 
ATP binding
 
|
 
GOA:interpro<br />GO_REF:0000002
 
|
 
IEA: Inferred from Electronic Annotation
 
|
|-
InterPro:IPR001140
!align=left {{table heading style}} |Synonyms
|
||
F
 
|
|-
Seeded from [[EcoCyc]] (v14.0)
!align=left {{table heading style}} |Product description
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|-
!align=left {{table heading style}} |EC number (for enzymes)
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<protect><!--Nomenclature_notes--></protect>
===Notes===
 
 
==Function==
{{BacktoTop}}
<protect>
<big>'''Gene Ontology'''</big><br /><!--box uid=421aa90e079fa326b6494f812ad13e79.21674.B46aa4b479d593-->
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{|  id="B46aa4b479d593"  class=" tableEdit GO_table_product dataTable"  
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-  
|-  
|
|


GO:0005319
|
lipid transporter activity
GO:0005524
GOA:hamap<br />GO_REF:0000020
|
ATP binding
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
HAMAP:MF_01703
|
InterPro:IPR003439
|
F
F
|
Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0005524
|
ATP binding
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011527
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0005524
|
ATP binding
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011917
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0005524
|
ATP binding
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR017871
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0005524
|
ATP binding
|
GOA:spkw<br />SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0067
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0005886
|
plasma membrane
|
GOA:spkw<br />SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0997
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0005886
|
plasma membrane
|
GOA:spkw<br />SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-1003
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0006869
|
lipid transport
|
GOA:hamap<br />GO_REF:0000020
|
IEA: Inferred from Electronic Annotation
|
HAMAP:MF_01703
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0006869
|
lipid transport
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011917
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0006869
|
lipid transport
|
GOA:spkw<br />SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0445
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0016020
|
membrane
|
GOA:spkw<br />SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0472
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0016020
|
membrane
|
PMID:16858726
|
IDA: Inferred from Direct Assay
|


|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


 
|
|
 
GO:0016021
|
integral to membrane
|
|
 
GOA:interpro<br />GO_REF:0000002
|
|
 
IEA: Inferred from Electronic Annotation
|
|
 
InterPro:IPR001140
|
|
 
C
|
|
 
Seeded from [[EcoCyc]] (v14.0)
|
 
|
|
   
   
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|
|


GO:0005524
|
ATP binding
GO:0016021
|
integral to membrane
|
GOA:interpro<br />GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
InterPro:IPR001140
|
F
InterPro:IPR011527
|
C
|
Seeded from [[EcoCyc]] (v14.0)
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0016021
|
integral to membrane
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011917
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0016021
|
integral to membrane
|
GOA:spkw<br />SP_KW:GO_REF:0000004
|
IEA: Inferred from Electronic Annotation
|
SP_KW:KW-0812
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0016021
|
integral to membrane
|
GO_REF:0000023
|
IEA: Inferred from Electronic Annotation
|
SP_SL:SL-9909
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0055085
|
transmembrane transport
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR001140
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
|-
|


|
GO:0055085
|
transmembrane transport
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011527
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|


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<span id="Interactions"></span><big>'''Interactions'''</big>
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!|Partner Type!!Partner!!Notes!!References!!Evidence


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<!--Function_notes--></protect>
===Notes===




==Localization==
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!|Compartment!!Description!!Evidence!!Source!!Notes
|-
|
plasma membrane
|
C-terminus localized in the cytoplasm with 6 predicted transmembrane domains
|
Daley et al. (2005) <ref name=PMID:15919996/>
|


|


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<protect><!--Localization_notes--></protect>


===Notes===




==Structure and Physical Properties==
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<protect>
<span id="Sequence"></span><big>'''Physical Properties'''</big>
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|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=EG10613-MONOMER at EcoCyc]
<pre>MHNDKDLSTW QTFRRLWPTI APFKAGLIVA GVALILNAAS DTFMLSLLKP LLDDGFGKTD
RSVLVWMPLV VIGLMILRGI TSYVSSYCIS WVSGKVVMTM RRRLFGHMMG MPVSFFDKQS
TGTLLSRITY DSEQVASSSS GALITVVREG ASIIGLFIMM FYYSWQLSII LIVLAPIVSI
AIRVVSKRFR NISKNMQNTM GQVTTSAEQM LKGHKEVLIF GGQEVETKRF DKVSNRMRLQ
GMKMVSASSI SDPIIQLIAS LALAFVLYAA SFPSVMDSLT AGTITVVFSS MIALMRPLKS
LTNVNAQFQR GMAACQTLFT ILDSEQEKDE GKRVIERATG DVEFRNVTFT YPGRDVPALR
NINLKIPAGK TVALVGRSGS GKSTIASLIT RFYDIDEGEI LMDGHDLREY TLASLRNQVA
LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL
LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS
TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ</pre>
|-
!align=left {{table heading style}} |Length
||
582
|-
!align=left {{table heading style}} |Mol. Wt
||
64.462 kDa
|-
!align=left {{table heading style}} |pI
||
8.8 (calculated)
|-
!align=left {{table heading style}} |Extinction coefficient
||
46,870 - 47,120 (calc based on 13 Y, 5 W, and 2 C residues)


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<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span>
<table>
<tr align="left" valign="top">
<td>


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!|Type!!Residues!!Description!!Notes!!References


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</td>
<td>
<!-- motifs column 2-->
<motif_map/>
{{TMHMM Picture|msbA}}
</td>
</tr>
</table>


<table><tr valign='top'><td>
<span id='Structure'></span><big>'''Structure'''</big><br />
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!align=left {{table heading style}} |Structures
||
<beststructure>
gene=msbA
taxon=562,83333
</beststructure>
|-
!align=left {{table heading style}} |Models
||
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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</td><td></protect>
==== Structure figures ====




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</td><tr><table><!--Structure_notes--></protect>
===Notes===




==Gene Product Resources==
{{BacktoTop}}
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!|Resource type!!Source!!Notes/Reference


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<protect><!--Resources_notes--></protect>
===Notes===




 
==Accessions in Other Databases==
 
{{BacktoTop}}
 
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!|Database!!Accession!!Notes
 
|-
 
|
 
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
 
|
 
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10613-MONOMER EcoCyc:EG10613-MONOMER]
 
|
 
   
 
|-  
 
|
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])  
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0005524
ATP binding
GOA:interpro<br />GO_REF:0000002
IEA: Inferred from Electronic Annotation
InterPro:IPR003439
F
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
    
|
 
|
 
|
 
|
 
|
 
|
 
|
   
|-  
|
 
GO:0005524
ATP binding
GOA:interpro<br />GO_REF:0000002
IEA: Inferred from Electronic Annotation
InterPro:IPR011527
F
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0005524
ATP binding
GOA:interpro<br />GO_REF:0000002
IEA: Inferred from Electronic Annotation
InterPro:IPR011917
F
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0005524
ATP binding
GOA:interpro<br />GO_REF:0000002
IEA: Inferred from Electronic Annotation
InterPro:IPR017871
F
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0005524
ATP binding
GOA:spkw<br />SP_KW:GO_REF:0000004
IEA: Inferred from Electronic Annotation
SP_KW:KW-0067
F
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0005886
plasma membrane
GOA:spkw<br />SP_KW:GO_REF:0000004
IEA: Inferred from Electronic Annotation
SP_KW:KW-0997
C
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0005886
plasma membrane
GOA:spkw<br />SP_KW:GO_REF:0000004
IEA: Inferred from Electronic Annotation
SP_KW:KW-1003
C
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0006869
lipid transport
GOA:hamap<br />GO_REF:0000020
IEA: Inferred from Electronic Annotation
HAMAP:MF_01703
P
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0006869
lipid transport
GOA:interpro<br />GO_REF:0000002
IEA: Inferred from Electronic Annotation
InterPro:IPR011917
P
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0006869
lipid transport
GOA:spkw<br />SP_KW:GO_REF:0000004
IEA: Inferred from Electronic Annotation
SP_KW:KW-0445
P
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0016020
membrane
GOA:spkw<br />SP_KW:GO_REF:0000004
IEA: Inferred from Electronic Annotation
SP_KW:KW-0472
C
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0016020
membrane
PMID:16858726
IDA: Inferred from Direct Assay
 
C
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0016021
integral to membrane
GOA:interpro<br />GO_REF:0000002
IEA: Inferred from Electronic Annotation
InterPro:IPR001140
C
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0016021
integral to membrane
GOA:interpro<br />GO_REF:0000002
IEA: Inferred from Electronic Annotation
InterPro:IPR011527
C
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0016021
integral to membrane
GOA:interpro<br />GO_REF:0000002
IEA: Inferred from Electronic Annotation
InterPro:IPR011917
C
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0005515
protein binding
PMID:18344567
IDA: Inferred from Direct Assay
 
C
 
complete
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0016021
integral to membrane
GOA:spkw<br />SP_KW:GO_REF:0000004
IEA: Inferred from Electronic Annotation
SP_KW:KW-0812
C
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0034040
lipid-transporting ATPase activity
PMID:18344567
IDA: Inferred from Direct Assay
 
F
 
complete
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0016021
integral to membrane
GO_REF:0000023
IEA: Inferred from Electronic Annotation
SP_SL:SL-9909
C
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0008289
lipid binding
PMID:18344567
IDA: Inferred from Direct Assay
 
F
 
complete
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0055085
transmembrane transport
GOA:interpro<br />GO_REF:0000002
IEA: Inferred from Electronic Annotation
InterPro:IPR001140
P
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0008144
drug binding
PMID:18344567
IDA: Inferred from Direct Assay
 
F
 
complete
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
|-
|
 
GO:0055085
transmembrane transport
GOA:interpro<br />GO_REF:0000002
IEA: Inferred from Electronic Annotation
InterPro:IPR011527
P
Seeded from [[EcoCyc]] (v14.0)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|
 
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.B46aa4b479d593&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</span> || || || || || || || ||
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.B46aa4b479d593-->
 
<span id="Interactions"></span><big>'''Interactions'''</big>
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.S46aa4b481bdb2-->
<!--
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*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Product_interactions_help}}
{|  id="S46aa4b481bdb2"  class=" tableEdit Product_interactions_table dataTable" 
|- {{table heading style}}
!|Partner Type!!Partner!!Notes!!References!!Evidence
 
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.S46aa4b481bdb2&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table]</span> || || || ||
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.S46aa4b481bdb2-->
 
<!--Function_notes--></protect>
===Notes===
 
 
==Localization==
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.G46a7dd1c2b935-->
<!--
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*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Product_localization_help}}
{|  id="G46a7dd1c2b935"  class=" tableEdit Product_localization_table" 
|- {{table heading style}}
!|Compartment!!Description!!Evidence!!Source!!Notes
|-
|
plasma membrane
C-terminus localized in the cytoplasm with 6 predicted transmembrane domains
Daley et al. (2005) <ref name=PMID:15919996/>
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
 
|
 
|
 
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.G46a7dd1c2b935&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table]</span> || || || ||
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.G46a7dd1c2b935-->
 
<protect><!--Localization_notes--></protect>
 
===Notes===
 
 
==Structure and Physical Properties==
{{BacktoTop}}
<protect>
<span id="Sequence"></span><big>'''Physical Properties'''</big>
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.W46aa4b49d4e91-->
<!--
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*
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*
****************************************************************************************** -->{{Product_physical_properties_help}}
{|  id="W46aa4b49d4e91"  class=" tableEdit Product_phys_prop_table" 
 
|-
!align=left {{table heading style}} |Sequence
||
[http://biocyc.org/ECOLI/sequence-aa?object=EG10613-MONOMER at EcoCyc]
<pre>MHNDKDLSTW QTFRRLWPTI APFKAGLIVA GVALILNAAS DTFMLSLLKP LLDDGFGKTD
RSVLVWMPLV VIGLMILRGI TSYVSSYCIS WVSGKVVMTM RRRLFGHMMG MPVSFFDKQS
TGTLLSRITY DSEQVASSSS GALITVVREG ASIIGLFIMM FYYSWQLSII LIVLAPIVSI
AIRVVSKRFR NISKNMQNTM GQVTTSAEQM LKGHKEVLIF GGQEVETKRF DKVSNRMRLQ
GMKMVSASSI SDPIIQLIAS LALAFVLYAA SFPSVMDSLT AGTITVVFSS MIALMRPLKS
LTNVNAQFQR GMAACQTLFT ILDSEQEKDE GKRVIERATG DVEFRNVTFT YPGRDVPALR
NINLKIPAGK TVALVGRSGS GKSTIASLIT RFYDIDEGEI LMDGHDLREY TLASLRNQVA
LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL
LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS
TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ</pre>
582
64.462 kDa
8.8 (calculated)
46,870 - 47,120 (calc based on 13 Y, 5 W, and 2 C residues)
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|-
!align=left {{table heading style}} |Length
||
 
|-
!align=left {{table heading style}} |Mol. Wt
||
 
|-
!align=left {{table heading style}} |pI
||
 
|-
!align=left {{table heading style}} |Extinction coefficient
||
 
 
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.W46aa4b49d4e91&page=21674&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table]</span> ||
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.W46aa4b49d4e91-->
 
 
<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span>
<table>
<tr align="left" valign="top">
<td>
 
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.M46aa4b4a3c914-->
<!--
******************************************************************************************
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
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{|  id="M46aa4b4a3c914"  class=" tableEdit Product_motif_table dataTable" 
|- {{table heading style}}
!|Type!!Residues!!Description!!Notes!!References
 
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.M46aa4b4a3c914&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table]</span> || || || ||
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.M46aa4b4a3c914-->
 
</td>
<td>
<!-- motifs column 2-->
<motif_map/>
{{TMHMM Picture|msbA}}
</td>
</tr>
</table>
 
<table><tr valign='top'><td>
<span id='Structure'></span><big>'''Structure'''</big><br />
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.A46a7dd1dc9beb-->
<!--
******************************************************************************************
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Product_structure_help}}
{|  id="A46a7dd1dc9beb"  class=" tableEdit Product_structure_table" 
 
|-
!align=left {{table heading style}} |Structures
||
<beststructure>
gene=msbA
taxon=562,83333
</beststructure>
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
 
 
 
 
 
 
 
 
 
|-
!align=left {{table heading style}} |Models
||
 
 
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.A46a7dd1dc9beb&page=21674&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table]</span> ||
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.A46a7dd1dc9beb-->
 
</td><td></protect>
==== Structure figures ====
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
<protect><!--          ***** PLEASE DO NOT EDIT BELOW THIS LINE *****        -->
</td><tr><table><!--Structure_notes--></protect>
===Notes===
 
 
==Gene Product Resources==
{{BacktoTop}}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.Q46aa4b4ad5f6c-->
<!--
******************************************************************************************
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Product_resources_help}}
{|  id="Q46aa4b4ad5f6c"  class=" tableEdit Product_resource_table" 
|- {{table_heading_style}}
!|Resource type!!Source!!Notes/Reference
 
|- class="tableEdit_footer"
|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.21674.Q46aa4b4ad5f6c&page=21674&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table]</span> || ||
|}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.Q46aa4b4ad5f6c-->
 
<protect><!--Resources_notes--></protect>
===Notes===
 
 
==Accessions in Other Databases==
{{BacktoTop}}
<!--box uid=421aa90e079fa326b6494f812ad13e79.21674.C46aa4b4b2e146-->
<!--
******************************************************************************************
*
*  ** PLEASE DON'T EDIT THIS TABLE DIRECTLY.  Use the edit table link under the table. **
*
****************************************************************************************** -->{{Gene_accessions_help}}
{|  id="C46aa4b4b2e146"  class=" tableEdit Gene_accessions_table" 
|- {{table_heading_style}}
!|Database!!Accession!!Notes
|-
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10613-MONOMER EcoCyc:EG10613-MONOMER]
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
|
 
|
|-
|
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
[[uniprot:P60752|UniProt:P60752]]
[[uniprot:P60752|UniProt:P60752]]
 
|
 
|
|
   
   
Line 2,963: Line 803:
|
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])  
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])  
|
[http://pfam.sanger.ac.uk/family?acc=PF00664 PFAM:PF00664]
[http://pfam.sanger.ac.uk/family?acc=PF00664 PFAM:PF00664]
 
|
 
|
|-
|
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])  
|-
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])  
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415434 RefSeq:NP_415434]
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415434 RefSeq:NP_415434]
 
|
 
|
|
   
   

Revision as of 23:07, 18 June 2010

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MsbA

Synonyms

fused lipid transporter subunits of ABC superfamily: membrane component[1], ATP-binding component[1], B0914[2][1], MsbA[2][1]

Product description

ATP-binding transport protein[2][3]

Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase[4]

EC number (for enzymes)



Notes

Function

[back to top]


Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

PMID:18344567[5]

IDA: Inferred from Direct Assay

C

complete

GO:0034040

lipid-transporting ATPase activity

PMID:18344567[5]

IDA: Inferred from Direct Assay

F

complete

GO:0008289

lipid binding

PMID:18344567[5]

IDA: Inferred from Direct Assay

F

complete

GO:0008144

drug binding

PMID:18344567[5]

IDA: Inferred from Direct Assay

F

complete

GO:0005319

lipid transporter activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01703

F

Seeded from EcoCyc (v14.0)

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

F

Seeded from EcoCyc (v14.0)

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003439

F

Seeded from EcoCyc (v14.0)

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011527

F

Seeded from EcoCyc (v14.0)

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011917

F

Seeded from EcoCyc (v14.0)

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017871

F

Seeded from EcoCyc (v14.0)

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

GO:0006869

lipid transport

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01703

P

Seeded from EcoCyc (v14.0)

GO:0006869

lipid transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011917

P

Seeded from EcoCyc (v14.0)

GO:0006869

lipid transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0445

P

Seeded from EcoCyc (v14.0)

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

GO:0016020

membrane

PMID:16858726[6]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc (v14.0)

GO:0016021

integral to membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

C

Seeded from EcoCyc (v14.0)

GO:0016021

integral to membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011527

C

Seeded from EcoCyc (v14.0)

GO:0016021

integral to membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011917

C

Seeded from EcoCyc (v14.0)

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

GO:0055085

transmembrane transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001140

P

Seeded from EcoCyc (v14.0)

GO:0055085

transmembrane transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011527

P

Seeded from EcoCyc (v14.0)


Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 6 predicted transmembrane domains

Daley et al. (2005) [7]



Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc

MHNDKDLSTW QTFRRLWPTI APFKAGLIVA GVALILNAAS DTFMLSLLKP LLDDGFGKTD
RSVLVWMPLV VIGLMILRGI TSYVSSYCIS WVSGKVVMTM RRRLFGHMMG MPVSFFDKQS
TGTLLSRITY DSEQVASSSS GALITVVREG ASIIGLFIMM FYYSWQLSII LIVLAPIVSI
AIRVVSKRFR NISKNMQNTM GQVTTSAEQM LKGHKEVLIF GGQEVETKRF DKVSNRMRLQ
GMKMVSASSI SDPIIQLIAS LALAFVLYAA SFPSVMDSLT AGTITVVFSS MIALMRPLKS
LTNVNAQFQR GMAACQTLFT ILDSEQEKDE GKRVIERATG DVEFRNVTFT YPGRDVPALR
NINLKIPAGK TVALVGRSGS GKSTIASLIT RFYDIDEGEI LMDGHDLREY TLASLRNQVA
LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL
LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS
TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ
Length

582

Mol. Wt

64.462 kDa

pI

8.8 (calculated)

Extinction coefficient

46,870 - 47,120 (calc based on 13 Y, 5 W, and 2 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

<motif_map/>

tmhmm.php?gene=msbA&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=msbA taxon=562,83333 </beststructure>

Models

View models at:

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference


Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:EG10613-MONOMER

UniProt (EcoliWiki Page)

UniProt:P60752

PFAM (EcoliWiki Page)

PFAM:PF00664

RefSeq (EcoliWiki Page)

RefSeq:NP_415434



Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 Eckford, PD & Sharom, FJ (2008) Functional characterization of Escherichia coli MsbA: interaction with nucleotides and substrates. J. Biol. Chem. 283 12840-50 PubMed
  6. ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
  7. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed

Categories

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