msbA:Gene Product(s): Difference between revisions
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MsbA | MsbA | ||
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!align=left {{table heading style}} |Synonyms | |||
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fused lipid transporter subunits of ABC superfamily: membrane component<ref name='LIB:Riley_2006'/>, ATP-binding component<ref name='LIB:Riley_2006'/>, B0914<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | fused lipid transporter subunits of ABC superfamily: membrane component<ref name='LIB:Riley_2006'/>, ATP-binding component<ref name='LIB:Riley_2006'/>, B0914<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MsbA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ||
|- | |||
!align=left {{table heading style}} |Product description | |||
|| | |||
ATP-binding transport protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | ATP-binding transport protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/> | ||
Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase<ref name='LIB:EcoGene'/> | Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase<ref name='LIB:EcoGene'/> | ||
|- | |||
!align=left {{table heading style}} |EC number (for enzymes) | |||
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<protect><!--Nomenclature_notes--></protect> | |||
===Notes=== | |||
==Function== | |||
{{BacktoTop}} | |||
<protect> | |||
<big>'''Gene Ontology'''</big><br /><!--box uid=421aa90e079fa326b6494f812ad13e79.21674.B46aa4b479d593--> | |||
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{| id="B46aa4b479d593" class=" tableEdit GO_table_product dataTable" | |||
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status | |||
|- | |||
| | |||
| | |||
GO:0005515 | |||
| | |||
protein binding | |||
| | |||
PMID:18344567 | |||
| | |||
IDA: Inferred from Direct Assay | |||
| | |||
| | |||
C | |||
| | |||
| | |||
complete | |||
|- | |||
| | |||
| | |||
GO:0034040 | |||
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lipid-transporting ATPase activity | |||
| | |||
PMID:18344567 | |||
| | |||
IDA: Inferred from Direct Assay | |||
| | |||
| | |||
F | |||
| | |||
| | |||
complete | |||
|- | |||
| | |||
| | |||
GO:0008289 | |||
| | |||
lipid binding | |||
| | |||
PMID:18344567 | |||
| | |||
IDA: Inferred from Direct Assay | |||
| | |||
| | |||
F | |||
| | |||
| | |||
complete | |||
|- | |||
| | |||
| | |||
GO:0008144 | |||
| | |||
drug binding | |||
| | |||
PMID:18344567 | |||
| | |||
IDA: Inferred from Direct Assay | |||
| | |||
| | |||
F | |||
| | |||
| | |||
complete | |||
|- | |||
| | |||
| | |||
GO:0005319 | |||
| | |||
lipid transporter activity | |||
| | |||
GOA:hamap<br />GO_REF:0000020 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
HAMAP:MF_01703 | |||
| | |||
F | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0005524 | |||
| | |||
ATP binding | |||
| | |||
GOA:interpro<br />GO_REF:0000002 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
| | InterPro:IPR001140 | ||
| | |||
F | |||
| | |||
| | Seeded from [[EcoCyc]] (v14.0) | ||
| | |||
| | |||
| | |||
| | |||
| | |||
|- | |- | ||
| | | | ||
GO: | | | ||
GO:0005524 | |||
GOA: | | | ||
ATP binding | |||
| | |||
GOA:interpro<br />GO_REF:0000002 | |||
| | |||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | |||
InterPro:IPR003439 | |||
| | |||
F | F | ||
| | |||
Seeded from [[EcoCyc]] (v14.0) | Seeded from [[EcoCyc]] (v14.0) | ||
| | |||
|- | |||
| | |||
| | |||
GO:0005524 | |||
| | |||
ATP binding | |||
| | |||
GOA:interpro<br />GO_REF:0000002 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
InterPro:IPR011527 | |||
| | |||
F | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0005524 | |||
| | |||
ATP binding | |||
| | |||
GOA:interpro<br />GO_REF:0000002 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
InterPro:IPR011917 | |||
| | |||
F | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0005524 | |||
| | |||
ATP binding | |||
| | |||
GOA:interpro<br />GO_REF:0000002 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
InterPro:IPR017871 | |||
| | |||
F | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0005524 | |||
| | |||
ATP binding | |||
| | |||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
SP_KW:KW-0067 | |||
| | |||
F | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0005886 | |||
| | |||
plasma membrane | |||
| | |||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
SP_KW:KW-0997 | |||
| | |||
C | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0005886 | |||
| | |||
plasma membrane | |||
| | |||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
SP_KW:KW-1003 | |||
| | |||
C | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0006869 | |||
| | |||
lipid transport | |||
| | |||
GOA:hamap<br />GO_REF:0000020 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
HAMAP:MF_01703 | |||
| | |||
P | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0006869 | |||
| | |||
lipid transport | |||
| | |||
GOA:interpro<br />GO_REF:0000002 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
InterPro:IPR011917 | |||
| | |||
P | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0006869 | |||
| | |||
lipid transport | |||
| | |||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
SP_KW:KW-0445 | |||
| | |||
P | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0016020 | |||
| | |||
membrane | |||
| | |||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
SP_KW:KW-0472 | |||
| | |||
C | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0016020 | |||
| | |||
membrane | |||
| | |||
PMID:16858726 | |||
| | |||
IDA: Inferred from Direct Assay | |||
| | |||
| | |||
C | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | | | ||
GO:0016021 | |||
| | |||
integral to membrane | |||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | |||
| | | | ||
InterPro:IPR001140 | |||
| | | | ||
C | |||
| | | | ||
Seeded from [[EcoCyc]] (v14.0) | |||
| | | | ||
| Line 210: | Line 442: | ||
| | | | ||
GO: | | | ||
GO:0016021 | |||
| | |||
integral to membrane | |||
| | |||
GOA:interpro<br />GO_REF:0000002 | GOA:interpro<br />GO_REF:0000002 | ||
| | |||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
InterPro: | | | ||
InterPro:IPR011527 | |||
| | |||
C | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | Seeded from [[EcoCyc]] (v14.0) | ||
| | |||
|- | |||
| | |||
| | |||
GO:0016021 | |||
| | |||
integral to membrane | |||
| | |||
GOA:interpro<br />GO_REF:0000002 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
InterPro:IPR011917 | |||
| | |||
C | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0016021 | |||
| | |||
integral to membrane | |||
| | |||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
SP_KW:KW-0812 | |||
| | |||
C | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0016021 | |||
| | |||
integral to membrane | |||
| | |||
GO_REF:0000023 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
SP_SL:SL-9909 | |||
| | |||
C | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0055085 | |||
| | |||
transmembrane transport | |||
| | |||
GOA:interpro<br />GO_REF:0000002 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
InterPro:IPR001140 | |||
| | |||
P | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
|- | |||
| | |||
| | |||
GO:0055085 | |||
| | |||
transmembrane transport | |||
| | |||
GOA:interpro<br />GO_REF:0000002 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
InterPro:IPR011527 | |||
| | |||
P | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
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<span id="Interactions"></span><big>'''Interactions'''</big> | |||
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{| id="S46aa4b481bdb2" class=" tableEdit Product_interactions_table dataTable" | |||
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!|Partner Type!!Partner!!Notes!!References!!Evidence | |||
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===Notes=== | |||
==Localization== | |||
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!|Compartment!!Description!!Evidence!!Source!!Notes | |||
|- | |||
| | |||
plasma membrane | |||
| | |||
C-terminus localized in the cytoplasm with 6 predicted transmembrane domains | |||
| | |||
Daley et al. (2005) <ref name=PMID:15919996/> | |||
| | |||
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<protect><!--Localization_notes--></protect> | |||
===Notes=== | |||
==Structure and Physical Properties== | |||
{{BacktoTop}} | |||
<protect> | |||
<span id="Sequence"></span><big>'''Physical Properties'''</big> | |||
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!align=left {{table heading style}} |Sequence | |||
|| | |||
[http://biocyc.org/ECOLI/sequence-aa?object=EG10613-MONOMER at EcoCyc] | |||
<pre>MHNDKDLSTW QTFRRLWPTI APFKAGLIVA GVALILNAAS DTFMLSLLKP LLDDGFGKTD | |||
RSVLVWMPLV VIGLMILRGI TSYVSSYCIS WVSGKVVMTM RRRLFGHMMG MPVSFFDKQS | |||
TGTLLSRITY DSEQVASSSS GALITVVREG ASIIGLFIMM FYYSWQLSII LIVLAPIVSI | |||
AIRVVSKRFR NISKNMQNTM GQVTTSAEQM LKGHKEVLIF GGQEVETKRF DKVSNRMRLQ | |||
GMKMVSASSI SDPIIQLIAS LALAFVLYAA SFPSVMDSLT AGTITVVFSS MIALMRPLKS | |||
LTNVNAQFQR GMAACQTLFT ILDSEQEKDE GKRVIERATG DVEFRNVTFT YPGRDVPALR | |||
NINLKIPAGK TVALVGRSGS GKSTIASLIT RFYDIDEGEI LMDGHDLREY TLASLRNQVA | |||
LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL | |||
LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS | |||
TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ</pre> | |||
|- | |||
!align=left {{table heading style}} |Length | |||
|| | |||
582 | |||
|- | |||
!align=left {{table heading style}} |Mol. Wt | |||
|| | |||
64.462 kDa | |||
|- | |||
!align=left {{table heading style}} |pI | |||
|| | |||
8.8 (calculated) | |||
|- | |||
!align=left {{table heading style}} |Extinction coefficient | |||
|| | |||
46,870 - 47,120 (calc based on 13 Y, 5 W, and 2 C residues) | |||
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<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span> | |||
<table> | |||
<tr align="left" valign="top"> | |||
<td> | |||
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</td> | |||
<td> | |||
<!-- motifs column 2--> | |||
<motif_map/> | |||
{{TMHMM Picture|msbA}} | |||
</td> | |||
</tr> | |||
</table> | |||
<table><tr valign='top'><td> | |||
<span id='Structure'></span><big>'''Structure'''</big><br /> | |||
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!align=left {{table heading style}} |Structures | |||
|| | |||
<beststructure> | |||
gene=msbA | |||
taxon=562,83333 | |||
</beststructure> | |||
|- | |||
!align=left {{table heading style}} |Models | |||
|| | |||
View models at: | |||
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict] | |||
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase] | |||
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED] | |||
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS) | |||
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP) | |||
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</td><td></protect> | |||
==== Structure figures ==== | |||
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<protect><!-- ***** PLEASE DO NOT EDIT BELOW THIS LINE ***** --> | |||
</td><tr><table><!--Structure_notes--></protect> | |||
===Notes=== | |||
==Gene Product Resources== | |||
{{BacktoTop}} | |||
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===Notes=== | |||
==Accessions in Other Databases== | |||
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[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]]) | |||
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[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10613-MONOMER EcoCyc:EG10613-MONOMER] | |||
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[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]]) | |||
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[[uniprot:P60752|UniProt:P60752]] | [[uniprot:P60752|UniProt:P60752]] | ||
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[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]]) | [http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]]) | ||
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[http://pfam.sanger.ac.uk/family?acc=PF00664 PFAM:PF00664] | [http://pfam.sanger.ac.uk/family?acc=PF00664 PFAM:PF00664] | ||
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[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]]) | |||
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[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]]) | |||
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[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415434 RefSeq:NP_415434] | [http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415434 RefSeq:NP_415434] | ||
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Revision as of 23:07, 18 June 2010
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
MsbA |
|---|---|
| Synonyms |
fused lipid transporter subunits of ABC superfamily: membrane component[1], ATP-binding component[1], B0914[2][1], MsbA[2][1] |
| Product description |
ATP-binding transport protein[2][3] Lipid exporter to the outer membrane; exports LPS, phospholipids, and lipid A; drug export and resistance; ABC transporter flippase; biogenesis of outer membrane; lipid-activated ATPase[4] |
| EC number (for enzymes) |
|
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
IDA: Inferred from Direct Assay |
C |
complete | ||||
| GO:0034040 |
lipid-transporting ATPase activity |
IDA: Inferred from Direct Assay |
F |
complete | ||||
| GO:0008289 |
lipid binding |
IDA: Inferred from Direct Assay |
F |
complete | ||||
| GO:0008144 |
drug binding |
IDA: Inferred from Direct Assay |
F |
complete | ||||
| GO:0005319 |
lipid transporter activity |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
|||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
|||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
|||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
|||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
|||
| GO:0005524 |
ATP binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
|||
| GO:0005524 |
ATP binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
|||
| GO:0005886 |
plasma membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
|||
| GO:0005886 |
plasma membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
|||
| GO:0006869 |
lipid transport |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
|||
| GO:0006869 |
lipid transport |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
|||
| GO:0006869 |
lipid transport |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
|||
| GO:0016020 |
membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
|||
| GO:0016020 |
membrane |
IDA: Inferred from Direct Assay |
C |
Seeded from EcoCyc (v14.0) |
||||
| GO:0016021 |
integral to membrane |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
|||
| GO:0016021 |
integral to membrane |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
|||
| GO:0016021 |
integral to membrane |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
|||
| GO:0016021 |
integral to membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
|||
| GO:0016021 |
integral to membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-9909 |
C |
Seeded from EcoCyc (v14.0) |
|||
| GO:0055085 |
transmembrane transport |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
|||
| GO:0055085 |
transmembrane transport |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
| ||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Source | Notes |
|---|---|---|---|---|
|
plasma membrane |
C-terminus localized in the cytoplasm with 6 predicted transmembrane domains |
Daley et al. (2005) [7] |
| |
| edit table |
Notes
Structure and Physical Properties
Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Sequence |
MHNDKDLSTW QTFRRLWPTI APFKAGLIVA GVALILNAAS DTFMLSLLKP LLDDGFGKTD RSVLVWMPLV VIGLMILRGI TSYVSSYCIS WVSGKVVMTM RRRLFGHMMG MPVSFFDKQS TGTLLSRITY DSEQVASSSS GALITVVREG ASIIGLFIMM FYYSWQLSII LIVLAPIVSI AIRVVSKRFR NISKNMQNTM GQVTTSAEQM LKGHKEVLIF GGQEVETKRF DKVSNRMRLQ GMKMVSASSI SDPIIQLIAS LALAFVLYAA SFPSVMDSLT AGTITVVFSS MIALMRPLKS LTNVNAQFQR GMAACQTLFT ILDSEQEKDE GKRVIERATG DVEFRNVTFT YPGRDVPALR NINLKIPAGK TVALVGRSGS GKSTIASLIT RFYDIDEGEI LMDGHDLREY TLASLRNQVA LVSQNVHLFN DTVANNIAYA RTEQYSREQI EEAARMAYAM DFINKMDNGL DTVIGENGVL LSGGQRQRIA IARALLRDSP ILILDEATSA LDTESERAIQ AALDELQKNR TSLVIAHRLS TIEKADEIVV VEDGVIVERG THNDLLEHRG VYAQLHKMQF GQ |
|---|---|
| Length |
582 |
| Mol. Wt |
64.462 kDa |
| pI |
8.8 (calculated) |
| Extinction coefficient |
46,870 - 47,120 (calc based on 13 Y, 5 W, and 2 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
|
Structure figures
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
| ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 5.2 5.3 Eckford, PD & Sharom, FJ (2008) Functional characterization of Escherichia coli MsbA: interaction with nucleotides and substrates. J. Biol. Chem. 283 12840-50 PubMed
- ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
- ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
Categories
- GO:0005515 ! protein binding
- GO:0034040 ! ATPase-coupled lipid transmembrane transporter activity
- GO:0008289 ! lipid binding
- GO:0008144 ! drug binding
- GO:0005319 ! lipid transporter activity
- GO:0005524 ! ATP binding
- GO:0005886 ! plasma membrane
- GO:0006869 ! lipid transport
- GO:0016020 ! membrane
- GO:0016021 ! integral component of membrane
- GO:0055085 ! transmembrane transport
- TMHMM Prediction
- Proteins
- RefGenome Annotated Gene
