prs:Gene Product(s): Difference between revisions

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|-
|-
!align=left {{table heading style}} |Standard name
!align=left |Standard name
||
||
PrsA  
PrsA  
|-
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!align=left {{table heading style}} |Synonyms
!align=left |Synonyms
||
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phosphoribosylpyrophosphate synthase<ref name='LIB:Riley_2006'/>, B1207<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DnaR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Prs<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PrsA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
phosphoribosylpyrophosphate synthase<ref name='LIB:Riley_2006'/>, B1207<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, DnaR<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Prs<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PrsA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
|-
|-
!align=left {{table heading style}} |Product description
!align=left |Product description
||
||


Phosphoribosylpyrophosphate synthase<ref name='LIB:EcoGene'/>
Phosphoribosylpyrophosphate synthase<ref name='LIB:EcoGene'/>
|-
|-
!align=left {{table heading style}} |EC number (for enzymes)
!align=left |EC number (for enzymes)
||
||
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.1 2.7.6.1]<ref name='LIB:Riley_2006'/>
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.6.1 2.7.6.1]<ref name='LIB:Riley_2006'/>


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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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required fields missing   


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!|Partner Type!!Partner!!Notes!!References!!Evidence
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Experiment(s):EBI-1139177<br />  
Experiment(s):EBI-1139177<br />  


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!|Compartment!!Description!!Evidence!!Source!!Notes
!|Compartment!!Description!!Evidence!!Source!!Notes


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|-
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!align=left {{table heading style}} |Sequence
!align=left |Sequence
||
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[http://biocyc.org/ECOLI/sequence-aa?object=PRPPSYN-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=PRPPSYN-MONOMER at EcoCyc]  
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RRISNEESIS AMFEH</pre>  
RRISNEESIS AMFEH</pre>  
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!align=left {{table heading style}} |Length
!align=left |Length
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315
315
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!align=left {{table heading style}} |Mol. Wt
!align=left |Mol. Wt
||
||
34.218 kDa
34.218 kDa
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!align=left {{table heading style}} |pI
!align=left |pI
||
||
5.2 (calculated)
5.2 (calculated)
|-
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!align=left {{table heading style}} |Extinction coefficient
!align=left |Extinction coefficient
||
||
5,960 - 6,460 (calc based on 4 Y,  W, and 4 C residues)
5,960 - 6,460 (calc based on 4 Y,  W, and 4 C residues)


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[http://www.uniprot.org/uniprot/P0A717#section_features UniProt:P0A717]  
[http://www.uniprot.org/uniprot/P0A717#section_features UniProt:P0A717]  


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<beststructure>
<beststructure>
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</beststructure>
</beststructure>
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!align=left {{table heading style}} |Models
!align=left |Models
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View models at:
View models at:
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* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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Revision as of 05:23, 9 January 2010

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

PrsA

Synonyms

phosphoribosylpyrophosphate synthase[1], B1207[2][1], DnaR[2][1], Prs[2][1], PrsA[2][1]

Product description

Phosphoribosylpyrophosphate synthase[3]

EC number (for enzymes)
edit table


Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:P0A6F5

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:P0A7D1

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:P0A9Q1

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:P0A9T6

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:P0AF63

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:P13458

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:P36767

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:P39176

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:P60390

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q47005

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005515

protein binding

PMID:16606699[4]

IPI: Inferred from Physical Interaction

UniProtKB:Q47156

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0005737

cytoplasm

PMID:16858726[6]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc 12.5 [5]

complete

GO:0046872

metal ion binding

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded from EcoCyc [7]

complete

GO:0016740

transferase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc [7]

complete

GO:0016301

kinase activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

Seeded from EcoCyc [7]

complete

GO:0009165

nucleotide biosynthetic process

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR005946
SP_KW:KW-0545

P

Seeded from EcoCyc [7]

complete

GO:0009156

ribonucleoside monophosphate biosynthetic process

GO_REF:0000002
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR000842
HAMAP:MF_00583

P

Seeded from EcoCyc 12.5 [5]

complete

GO:0009116

nucleoside metabolic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000836

P

Seeded from EcoCyc [7]

complete

GO:0005737

cytoplasm

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc 12.5 [5]

complete

GO:0004749

ribose phosphate diphosphokinase activity

GO_REF:0000002
GO_REF:0000002
GO_REF:0000003
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR000842
InterPro:IPR005946
EC:2.7.6.1
HAMAP:MF_00583

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0000287

magnesium ion binding

GO_REF:0000002
GO_REF:0000002
GO_REF:0000004
GO_REF:0000020

IEA: Inferred from Electronic Annotation

InterPro:IPR000842
InterPro:IPR005946
SP_KW:KW-0460
HAMAP:MF_00583

F

Seeded from EcoCyc 12.5 [5]

complete

GO:0044249

cellular biosynthetic process

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000842

P

Seeded from EcoCyc [7]

complete

GO:0009152

purine ribonucleotide biosynthetic process

P

Seeded from EcoCyc 11.1[8].

required fields missing

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

npdA

PMID:15690043[9]

Experiment(s):EBI-880430, EBI-881344, EBI-885898

Protein

dnaJ

PMID:15690043[9]

Experiment(s):EBI-880430, EBI-885898

Protein

dnaK

PMID:15690043[9]

Experiment(s):EBI-880430

Protein

groL

PMID:15690043[9]

Experiment(s):EBI-880430, EBI-885898

Protein

mreB

PMID:15690043[9]

Experiment(s):EBI-880430

Protein

rplB

PMID:15690043[9]

Experiment(s):EBI-880430, EBI-885898

Protein

rplE

PMID:15690043[9]

Experiment(s):EBI-880430

Protein

rplJ

PMID:15690043[9]

Experiment(s):EBI-880430

Protein

rplP

PMID:15690043[9]

Experiment(s):EBI-880430, EBI-885898

Protein

rpsB

PMID:15690043[9]

Experiment(s):EBI-880430, EBI-885898

Protein

rpsC

PMID:15690043[9]

Experiment(s):EBI-880430, EBI-885898

Protein

rpsD

PMID:15690043[9]

Experiment(s):EBI-880430, EBI-885898

Protein

rpsG

PMID:15690043[9]

Experiment(s):EBI-880430, EBI-885898

Protein

tufA

PMID:15690043[9]

Experiment(s):EBI-880430, EBI-885898

Protein

rluB

PMID:15690043[9]

Experiment(s):EBI-880430

Protein

yibA

PMID:15690043[9]

Experiment(s):EBI-880430

Protein

nusG

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rho

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplC

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplD

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplI

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplK

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplL

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplM

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplN

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplO

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplS

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplU

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplV

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplW

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rplX

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rpmB

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rpsE

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rpsH

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rpsJ

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rpsP

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

rpsT

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

yfiF

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

yrfD

PMID:15690043[9]

Experiment(s):EBI-885898

Protein

groL

PMID:16606699[4]

Experiment(s):EBI-1139177
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MPDMKLFAGN ATPELAQRIA NRLYTSLGDA AVGRFSDGEV SVQINENVRG GDIFIIQSTC
APTNDNLMEL VVMVDALRRA SAGRITAVIP YFGYARQDRR VRSARVPITA KVVADFLSSV
GVDRVLTVDL HAEQIQGFFD VPVDNVFGSP ILLEDMLQLN LDNPIVVSPD IGGVVRARAI
AKLLNDTDMA IIDKRRPRAN VSQVMHIIGD VAGRDCVLVD DMIDTGGTLC KAAEALKERG
AKRVFAYATH PIFSGNAANN LRNSVIDEVV VCDTIPLSDE IKSLPNVRTL TLSGMLAEAI
RRISNEESIS AMFEH
Length

315

Mol. Wt

34.218 kDa

pI

5.2 (calculated)

Extinction coefficient

5,960 - 6,460 (calc based on 4 Y, W, and 4 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes

Initiator Methionine

1

Removed

UniProt:P0A717

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=prs taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:PRPPSYN-MONOMER

SwissModel (EcoliWiki Page)

SwissModel:P0A717

UniProt (EcoliWiki Page)

UniProt:P0A717

PFAM (EcoliWiki Page)

PFAM:PF00156

RefSeq (EcoliWiki Page)

RefSeq:NP_415725


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  4. ↑ 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 4.11 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  6. ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
  7. ↑ 7.0 7.1 7.2 7.3 7.4 7.5 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  8. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  9. ↑ 9.00 9.01 9.02 9.03 9.04 9.05 9.06 9.07 9.08 9.09 9.10 9.11 9.12 9.13 9.14 9.15 9.16 9.17 9.18 9.19 9.20 9.21 9.22 9.23 9.24 9.25 9.26 9.27 9.28 9.29 9.30 9.31 9.32 9.33 9.34 9.35 9.36 9.37 9.38 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed

Categories

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