setB:Gene Product(s): Difference between revisions

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|-
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!align=left {{table heading style}} |Standard name
!align=left |Standard name
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SetB  
SetB  
|-
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!align=left {{table heading style}} |Synonyms
!align=left |Synonyms
||
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lactose/glucose efflux system<ref name='LIB:Riley_2006'/>, B2170<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YeiO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SetB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
lactose/glucose efflux system<ref name='LIB:Riley_2006'/>, B2170<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, YeiO<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, SetB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
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!align=left {{table heading style}} |Product description
!align=left |Product description
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SetB MFS transporter<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
SetB MFS transporter<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
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Glucose and lactose efflux transporter<ref name='LIB:EcoGene'/>
Glucose and lactose efflux transporter<ref name='LIB:EcoGene'/>
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!align=left {{table heading style}} |EC number (for enzymes)
!align=left |EC number (for enzymes)
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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complete  
complete  


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|-
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!align=left {{table heading style}} |Sequence
!align=left |Sequence
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[http://biocyc.org/ECOLI/sequence-aa?object=B2170-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=B2170-MONOMER at EcoCyc]  
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GIVAEIWNYH AVFWFAMVMI IATLFCLLRI KDV</pre>  
GIVAEIWNYH AVFWFAMVMI IATLFCLLRI KDV</pre>  
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!align=left {{table heading style}} |Length
!align=left |Length
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393
393
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!align=left {{table heading style}} |Mol. Wt
!align=left |Mol. Wt
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42.747 kDa
42.747 kDa
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!align=left {{table heading style}} |pI
!align=left |pI
||
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10.1 (calculated)
10.1 (calculated)
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!align=left {{table heading style}} |Extinction coefficient
!align=left |Extinction coefficient
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51,910 - 52,785 (calc based on 9 Y, 7 W, and 7 C residues)
51,910 - 52,785 (calc based on 9 Y, 7 W, and 7 C residues)


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<beststructure>
<beststructure>
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</beststructure>
</beststructure>
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!align=left {{table heading style}} |Models
!align=left |Models
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View models at:
View models at:
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* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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Revision as of 00:40, 10 January 2010

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

SetB

Synonyms

lactose/glucose efflux system[1], B2170[2][1], YeiO[2][1], SetB[2][1]

Product description

SetB MFS transporter[2][3]

Glucose and lactose efflux transporter[4]

EC number (for enzymes)


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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference(s) Evidence Code with/from Aspect Notes Status
GO:0016021

integral to membrane

GO_REF:0000002
GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR004750
InterPro:IPR007114
SP_KW:KW-0812

C

Seeded from EcoCyc [5]

complete

GO:0016020

membrane

GO_REF:0000004
GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0397
SP_KW:KW-0472

C

Seeded from EcoCyc 12.5 [6]

complete

GO:0015542

sugar efflux transmembrane transporter activity

GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004750

F

Seeded from EcoCyc 12.5 [6]

complete

GO:0008643

carbohydrate transport

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR004750
SP_KW:KW-0762

P

Seeded from EcoCyc [5]

complete

GO:0006810

transport

GO_REF:0000002
GO_REF:0000004

IEA: Inferred from Electronic Annotation

InterPro:IPR007114
SP_KW:KW-0813

P

Seeded from EcoCyc [5]

complete

GO:0005351

sugar:hydrogen symporter activity

GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0762

F

Seeded from EcoCyc [5]

complete

GO:0015767

lactose transport

PMID:10438463[7]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc [5]

complete

GO:0005886

plasma membrane

GO_REF:0000004
GO_REF:0000004
GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997
SP_KW:KW-1003
SP_SL:SL-0037

C

Seeded from EcoCyc [5]

complete

GO:0015292

uniporter activity

F

Seeded from EcoCyc 11.1[3].

required fields missing

GO:0015758

glucose transport

PMID:10438463[7]

IDA: Inferred from Direct Assay

P

Seeded from EcoCyc [5]

complete

GO:0007059

chromosome segregation

PMID:14617174[8]

IMP: Inferred from Mutant Phenotype

P

complete

GO:0016020

membrane

PMID:14617174[8]

IDA: Inferred from Direct Assay

C

complete

GO:0015767

lactose transport

PMID:10438463[7]

IDA: Inferred from Direct Assay

P

complete

GO:0015542

sugar efflux transmembrane transporter activity

PMID:10438463[7]

IDA: Inferred from Direct Assay

F

complete

GO:0015758

glucose transport

PMID:10438463[7]

IDA: Inferred from Direct Assay

P

complete

GO:0016020

membrane

PMID:10438463[7]

IDA: Inferred from Direct Assay

C

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

MreB

PMID:14617174[8]


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Source Notes

plasma membrane

C-terminus localized in the cytoplasm with 12 predicted transmembrane domains

Daley et al. (2005) [9]


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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Sequence

at EcoCyc 

MHNSPAVSSA KSFDLTSTAF LIVAFLTGIA GALQTPTLSI FLTDEVHARP AMVGFFFTGS
AVIGILVSQF LAGRSDKRGD RKSLIVFCCL LGVLACTLFA WNRNYFVLLF VGVFLSSFGS
TANPQMFALA REHADKTGRE AVMFSSFLRA QVSLAWVIGP PLAYALAMGF SFTVMYLSAA
VAFIVCGVMV WLFLPSMRKE LPLATGTIEA PRRNRRDTLL LFVICTLMWG SNSLYIINMP
LFIINELHLP EKLAGVMMGT AAGLEIPTML IAGYFAKRLG KRFLMRVAAV GGVCFYAGML
MAHSPVILLG LQLLNAIFIG ILGGIGMLYF QDLMPGQAGS ATTLYTNTSR VGWIIAGSVA
GIVAEIWNYH AVFWFAMVMI IATLFCLLRI KDV
Length

393

Mol. Wt

42.747 kDa

pI

10.1 (calculated)

Extinction coefficient

51,910 - 52,785 (calc based on 9 Y, 7 W, and 7 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes
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<motif_map/>

tmhmm.php?gene=setB&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=setB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

EcoCyc (EcoliWiki Page)

EcoCyc:B2170-MONOMER

UniProt (EcoliWiki Page)

UniProt:P33026

PFAM (EcoliWiki Page)

PFAM:PF07690

RefSeq (EcoliWiki Page)

RefSeq:NP_416675


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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 5.3 5.4 5.5 5.6 EcoCyc (release 13.0; 2009) Keseler, IM et al. (2009) Nucleic Acids Res. 37(Database issue):D464-70
  6. ↑ 6.0 6.1 EcoCyc (release 12.5; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  7. ↑ 7.0 7.1 7.2 7.3 7.4 7.5 Liu, JY et al. (1999) Functional and biochemical characterization of Escherichia coli sugar efflux transporters. J. Biol. Chem. 274 22977-84 PubMed
  8. ↑ 8.0 8.1 8.2 Espeli, O et al. (2003) SetB: an integral membrane protein that affects chromosome segregation in Escherichia coli. Mol. Microbiol. 50 495-509 PubMed
  9. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed

Categories

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