thiC:Gene Product(s): Difference between revisions
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!align=left {{table heading style}} |Synonyms | !align=left {{table heading style}} |Synonyms | ||
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thiamin (pyrimidine moiety) biosynthesis protein<ref name='LIB:Riley_2006'/>, B3994<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ThiC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ''thiamin (pyrimidine moiety) biosynthesis protein<ref name='LIB:Riley_2006'/>, B3994<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ThiC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3986, JW3958, b3994'' | ||
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!align=left {{table heading style}} |Product description | !align=left {{table heading style}} |Product description | ||
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!|Qualifier!!GO ID!!GO term name!!Reference | !|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status | ||
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thiamin biosynthetic process | thiamin biosynthetic process | ||
| | | | ||
GOA:hamap<br />GO_REF:0000020 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
HAMAP:MF_00089 | |||
| | | | ||
P | P | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | complete | ||
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thiamin biosynthetic process | thiamin biosynthetic process | ||
| | | | ||
GOA:interpro<br />GO_REF:0000002 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | IEA: Inferred from Electronic Annotation | ||
| | | | ||
InterPro:IPR002817 | |||
| | | | ||
P | P | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | |||
complete | |||
|- | |||
| | |||
| | |||
GO:0009228 | |||
| | |||
thiamin biosynthetic process | |||
| | |||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
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SP_KW:KW-0784 | |||
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P | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
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complete | complete | ||
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!|Partner Type!!Partner!!Notes!!References!!Evidence | !|Partner Type!!Partner!!Notes!!References!!Evidence | ||
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Experiment(s):EBI-1147221<br /> | Experiment(s):EBI-1147221<br /> | ||
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!|Compartment!!Description!!Evidence!!Notes | !|Compartment!!Description!!Evidence!!Reference/Source!!Notes | ||
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!align=left {{table heading style}} |Name | |||
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!align=left {{table heading style}} |Mol. Wt | !align=left {{table heading style}} |Mol. Wt | ||
|| | || | ||
70. | 70.851 kDa | ||
|- | |- | ||
!align=left {{table heading style}} |pI | !align=left {{table heading style}} |pI | ||
|| | || | ||
6. | 6.0 (calculated) | ||
|- | |- | ||
!align=left {{table heading style}} |Extinction coefficient | !align=left {{table heading style}} |Extinction coefficient | ||
|| | || | ||
79,300 - 80,425 (calc based on 20 Y, 9 W, and 9 C residues) | |||
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!|Type!!Residues!!Description!!Notes | !|Type!!Residues!!Description!!Notes!!References | ||
|- | |||
| | |||
Domain | |||
| | |||
148..598 | |||
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[http://pfam.janelia.org/family/PF01964 PF01964 ThiC family] | |||
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PMID:19920124 | |||
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<span id= | <table><tr valign='top'><td> | ||
<span id='Structure'></span><big>'''Structure'''</big><br /> | |||
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!align=left {{table heading style}} |Structures | !align=left {{table heading style}} |Structures | ||
|| | || | ||
<beststructure>thiC | <beststructure> | ||
562</beststructure> | gene=thiC | ||
taxon=562,83333 | |||
</beststructure> | |||
|- | |- | ||
!align=left {{table heading style}} |Models | !align=left {{table heading style}} |Models | ||
|| | || | ||
View models at: | View models at: | ||
* [http:// | * [http://www.proteinmodelportal.org/query/uniprot/P30136 Protein Model Portal] | ||
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P30136 PSI-PRED (P30136)] | |||
* [http://bioinf.cs.ucl.ac.uk/ | * [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P30136 Genomes TO Protein (P30136)] (GTOP) | ||
* [http://spock.genes.nig.ac.jp/~genome/ | |||
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==== Structure figures ==== | |||
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===Notes=== | ===Notes=== | ||
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!|Database!!Accession!!Notes | !|Database!!Accession!!Notes | ||
|- | |- | ||
| | | | ||
[http:// | [http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]]) | ||
| | | | ||
[http:// | [http://www.ncbi.nlm.nih.gov/protein/16131824 GI:16131824] | ||
| | | | ||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |||
| | |||
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]]) | |||
| | |||
[http://www.ncbi.nlm.nih.gov/protein/NP_418422.1 GeneID:948492] | |||
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Escherichia coli str. K-12 substr. MG1655 | |||
|- | |||
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[[ASAP]] | |||
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ASAP:ABE-0013057 | |||
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |||
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[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]]) | |||
| | |||
[http://www.uniprot.org/uniprot/P30136 UniProtKB/Swiss-Prot:P30136] | |||
| | |||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |||
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[[EcoCyc]] | |||
| | |||
EcoCyc:EG11585 | |||
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |||
| | |||
[[EcoGene]] | |||
| | |||
EcoGene:EG11585 | |||
| | |||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |- | ||
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[http:// | [http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]]) | ||
| | | | ||
[ | [http://www.ncbi.nlm.nih.gov/gene?term=948492 GeneID:948492] | ||
| | | | ||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |- | ||
| | | | ||
[[RegulonDB]] | |||
| | | | ||
RegulonDB:ECK120001535 | |||
| | | | ||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |- | ||
| | | | ||
[[EchoBASE]] | |||
| | | | ||
EchoBASE:EB1544 | |||
| | | | ||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
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==References== | ==References== | ||
{{BacktoTop}} | {{BacktoTop}} | ||
{{RefHelp}} | |||
<references/> | <references /> | ||
__NOTOC__ | __NOTOC__ | ||
===Categories=== | ===Categories=== | ||
{{BacktoTop}} | {{BacktoTop}} | ||
[[Category:Proteins]] | [[Category:Proteins]] | ||
Latest revision as of 21:11, 17 February 2015
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
ThiC |
|---|---|
| Synonyms |
thiamin (pyrimidine moiety) biosynthesis protein[1], B3994[2][1], ThiC[2][1] , ECK3986, JW3958, b3994 |
| Product description |
thiamin biosynthesis protein ThiC[2][3] Hydroxymethylpyrimidine synthesis, for thiamine biosynthesis[4] |
| EC number (for enzymes) |
|
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0009228 |
thiamin biosynthetic process |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009228 |
thiamin biosynthetic process |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009228 |
thiamin biosynthetic process |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
moaC |
Experiment(s):EBI-1147221 | ||
|
Protein |
glpD |
Experiment(s):EBI-1147221 | ||
|
Protein |
napG |
Experiment(s):EBI-1147221 | ||
|
Protein |
napC |
Experiment(s):EBI-1147221 | ||
|
Protein |
hycF |
Experiment(s):EBI-1147221 | ||
|
Protein |
hemG |
Experiment(s):EBI-1147221 | ||
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
Notes
Structure and Physical Properties
Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MSATKLTRRE QRARAQHFID TLEGTAFPNS KRIYITGTHP GVRVPMREIQ LSPTLIGGSK EQPQYEENEA IPVYDTSGPY GDPQIAINVQ QGLAKLRQPW IDARGDTEEL TVRSSDYTKA RLADDGLDEL RFSGVLTPKR AKAGRRVTQL HYARQGIITP EMEFIAIREN MGRERIRSEV LRHQHPGMSF GAHLPENITA EFVRDEVAAG RAIIPANINH PESEPMIIGR NFLVKVNANI GNSAVTSSIE EEVEKLVWST RWGADTVMDL STGRYIHETR EWILRNSPVP IGTVPIYQAL EKVNGIAEDL TWEAFRDTLL EQAEQGVDYF TIHAGVLLRY VPMTAKRLTG IVSRGGSIMA KWCLSHHQEN FLYQHFREIC EICAAYDVSL SLGDGLRPGS IQDANDEAQF AELHTLGELT KIAWEYDVQV MIEGPGHVPM QMIRRNMTEE LEHCHEAPFY TLGPLTTDIA PGYDHFTSGI GAAMIGWFGC AMLCYVTPKE HLGLPNKEDV KQGLITYKIA AHAADLAKGH PGAQIRDNAM SKARFEFRWE DQFNLALDPF TARAYHDETL PQESGKVAHF CSMCGPKFCS MKISQEVRDY AATQTIEMGM ADMSENFRAR GGEIYLRKEE A |
| Length |
631 |
| Mol. Wt |
70.851 kDa |
| pI |
6.0 (calculated) |
| Extinction coefficient |
79,300 - 80,425 (calc based on 20 Y, 9 W, and 9 C residues) |
| edit table |
Domains/Motifs/Modification Sites
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See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
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<motif_map/> |
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Structure
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Structure figures
Notes
Gene Product Resources
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| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
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Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
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