thiC:Quickview

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Standard Name

thiC

Gene Synonym(s)

ECK3986, b3994, JW3958[1], JW3958

Product Desc.

thiamin biosynthesis protein ThiC[2][3]

Hydroxymethylpyrimidine synthesis, for thiamine biosynthesis[4]

Product Synonyms(s)

thiamin (pyrimidine moiety) biosynthesis protein[1], B3994[2][1], ThiC[2][1] , ECK3986, JW3958, b3994

Function from GO

<GO_nr />

Knock-Out Phenotype
Regulation/Expression

transcription unit(s): thiCEFSGH[2]

Regulation/Activity
Quick Links

porteco.png EcoCyc.gif regulondb.jpg

dnadisplay.png proteindisplay.png   pubmed.jpg   textpresso.jpg  

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Notes

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thiCEFSGH operon expression is controlled by a thiamine pyrophosphate (TPP) responsive riboswitch in the 5' UTR. The thiC riboswitch is the target for the antibiotic pyrithiamine.[4]



References

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  1. 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. 4.0 4.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.