atpE:Gene Product(s): Difference between revisions

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!align=left {{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
||
||
F0 sector of membrane-bound ATP synthase, subunit c<ref name='LIB:Riley_2006'/>, B3737<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, UncE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PapH<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AtpE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, dicyclohexylcarbodiimide-binding protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, lipid-binding protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, c chain<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''F0 sector of membrane-bound ATP synthase, subunit c<ref name='LIB:Riley_2006'/>, B3737<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, UncE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, PapH<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, AtpE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, dicyclohexylcarbodiimide-binding protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, lipid-binding protein<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, c chain<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3730, JW3715, papH, uncE, b3737''
|-
|-
!align=left {{table heading style}} |Product description
!align=left {{table heading style}} |Product description
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* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14]<ref name='LIB:Riley_2006'/>
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.3.14 3.6.3.14]<ref name='LIB:Riley_2006'/>


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*  
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****************************************************************************************** -->{{Product_GO_help}}
****************************************************************************************** -->{{Product_GO_help}}
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="Z46ab00272071d"  class=" tableEdit GO_table_product dataTable"   
|- {{table_heading_style}}
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-  
|-  
|
|


|
|
GO:0006811
GO:0016021
|
|
ion transport
integral to membrane
|
|
GO_REF:0000004
PMID:2863271
|
|
IEA: Inferred from Electronic Annotation
IDA: Inferred from Direct Assay
|
|
SP_KW:KW-0406
 
|
|
P
C
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from Riley et  al 2006 <ref name='LIB:Riley_2006'/>.
|
|
complete  
complete  
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|
|
GO:0008289
GO:0005886
|
|
lipid binding
plasma membrane
|
|
GO_REF:0000004
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
SP_KW:KW-0446
SP_KW:KW-0997
|
|
F
C
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
|-  
|-  
|
|
 
Contributes to
|
|
GO:0006810
GO:0046961
|
|
transport
proton-transporting ATPase activity, rotational mechanism
|
|
GO_REF:0000004
PMID:2863271
|
|
IEA: Inferred from Electronic Annotation
IMP: Inferred from Mutant Phenotype
|
SP_KW:KW-0813
|
P
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
|
complete
|-
|
|


|
GO:0016820
|
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
|
GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR005953
|
|
F
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
 
|
|
complete  
complete  
Line 160: Line 141:


|
|
GO:0016469
GO:0005886
|
|
proton-transporting two-sector ATPase complex
plasma membrane
|
|
GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR000454<br />InterPro:IPR002379<br />InterPro:IPR005953
SP_KW:KW-1003
|
|
C
C
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0016021
GO:0045263
|
|
integral to membrane
proton-transporting ATP synthase complex, coupling factor F(o)
|
|
GO_REF:0000002<br />GO_REF:0000004
PMID:6460031
|
|
IEA: Inferred from Electronic Annotation
IMP: Inferred from Mutant Phenotype
|
|
InterPro:IPR005953<br />SP_KW:KW-0812
 
|
|
C
C
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
 
|
|
complete  
complete  
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|
|
GO:0015078
GO:0008289
|
|
hydrogen ion transmembrane transporter activity
lipid binding
|
|
GO_REF:0000004
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
SP_KW:KW-0375
SP_KW:KW-0446
|
|
F
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0015986
GO:0015078
|
|
ATP synthesis coupled proton transport
hydrogen ion transmembrane transporter activity
|
|
GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR000454<br />InterPro:IPR002379<br />InterPro:IPR005953
InterPro:IPR000454
|
|
P
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
Line 236: Line 217:


|
|
GO:0015992
GO:0015078
|
|
proton transport
hydrogen ion transmembrane transporter activity
|
|
GO_REF:0000004
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
SP_KW:KW-0375
InterPro:IPR002379
|
|
P
F
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
Line 255: Line 236:


|
|
GO:0016020
GO:0015078
|
|
membrane
hydrogen ion transmembrane transporter activity
|
|
GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004<br />GO_REF:0000004
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR000454<br />InterPro:IPR002379<br />SP_KW:KW-0397<br />SP_KW:KW-0472
InterPro:IPR005953
|
|
C
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
Line 274: Line 255:


|
|
GO:0045263
GO:0015986
|
|
proton-transporting ATP synthase complex, coupling factor F(o)
ATP synthesis coupled proton transport
|
|
GO_REF:0000004
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
SP_KW:KW-0138
InterPro:IPR000454
|
|
C
P
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0046933
GO:0015986
|
|
hydrogen ion transporting ATP synthase activity, rotational mechanism
ATP synthesis coupled proton transport
|
|
GO_REF:0000002<br />GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR000454<br />InterPro:IPR002379
InterPro:IPR002379
|
|
F
P
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
Line 312: Line 293:


|
|
GO:0046961
GO:0015986
|
|
hydrogen ion transporting ATPase activity, rotational mechanism
ATP synthesis coupled proton transport
|
|
GO_REF:0000002<br />GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR000454<br />InterPro:IPR002379
InterPro:IPR005953
|
|
F
P
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
Line 331: Line 312:


|
|
GO:0016021  
GO:0016021
|
|
integral to membrane
integral to membrane
|
|
PMID:2863271
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IDA: Inferred from Direct Assay
IEA: Inferred from Electronic Annotation
|
|
 
SP_KW:KW-0812
|
|
C
C
|
|
Seeded from Riley et  al 2006 <ref name='LIB:Riley_2006'/>.  
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
Line 350: Line 331:


|
|
GO:0005886
GO:0016021
|
|
plasma membrane
integral to membrane
|
|
GO_REF:0000004<br />GO_REF:0000004<br />GO_REF:0000023
GO_REF:0000023
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
SP_KW:KW-0997<br />SP_KW:KW-1003<br />SP_SL:SL-0037
SP_SL:SL-9909
|
|
C
C
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
Line 369: Line 350:


|
|
GO:0033177
GO:0045263
|
|
proton-transporting two-sector ATPase complex, proton-transporting domain
proton-transporting ATP synthase complex, coupling factor F(o)
|
|
GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR002379
InterPro:IPR000454
|
|
C
C
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
Line 388: Line 369:


|
|
GO:0005886
GO:0045263
|
|
plasma membrane
proton-transporting ATP synthase complex, coupling factor F(o)
|
|
GO_REF:0000004<br />GO_REF:0000004<br />GO_REF:0000023
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
SP_KW:KW-0997<br />SP_KW:KW-1003<br />SP_SL:SL-0037
InterPro:IPR005953
|
|
C
C
|
|
Seeded from EcoCyc
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0015986
|
ATP synthesis coupled proton transport
|
PMID:2863271
|
IMP: Inferred from Mutant Phenotype
|
 
|
P
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.  
|
complete
|-
|
Contributes to
|
GO:0046961
|
hydrogen ion transporting ATPase activity, rotational mechanism
|
PMID:2863271
|
IMP: Inferred from Mutant Phenotype
|
 
|
F
|
 
|
|
complete  
complete  
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proton-transporting ATP synthase complex, coupling factor F(o)
proton-transporting ATP synthase complex, coupling factor F(o)
|
|
PMID:6460031
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IMP: Inferred from Mutant Phenotype
IEA: Inferred from Electronic Annotation
|
|
 
SP_KW:KW-0138
|
|
C
C
|
|
 
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0006810
GO:0046933
|
|
transport
hydrogen ion transporting ATP synthase activity, rotational mechanism
|
|
GO_REF:0000004
GOA:hamap<br />GO_REF:0000020
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
SP_KW:KW-0813
HAMAP:MF_01396
|
|
P
F
|
|
Seeded from EcoCyc
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  


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****************************************************************************************** -->{{Product_interactions_help}}
****************************************************************************************** -->{{Product_interactions_help}}
{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"   
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="C46ab0034e902d"  class=" tableEdit Product_interactions_table dataTable"   
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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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****************************************************************************************** -->{{Product_localization_help}}
****************************************************************************************** -->{{Product_localization_help}}
{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"   
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="D46ab003764ef8"  class=" tableEdit Product_localization_table"   
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!|Compartment!!Description!!Evidence!!Notes
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
|-  
|-  
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|
Daley et al. (2005) <ref name=PMID:15919996/>
Daley et al. (2005) <ref name=PMID:15919996/>
|
|
|
   
   
Line 567: Line 512:
   
   
|
|
From EcoCyc<ref name='LIB:EcoCyc11.1'/>   
From EcoCyc<ref name='LIB:EcoCyc11.1'/>  
|
   
|-
|
Inner Membrane
|


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PMID:9237612
|
[http://www.york.ac.uk/res/thomas/Echolocation.cfm?EB_SubLocID=EB0100 EchoLocation:atpE]
|
 
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!align=left {{table heading style}} |Name
||


|-
|-
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!align=left {{table heading style}} |Mol. Wt
!align=left {{table heading style}} |Mol. Wt
||
||
8.26 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
8.256 kDa
|-
|-
!align=left {{table heading style}} |pI
!align=left {{table heading style}} |pI
||
||
4.69<ref name='LIB:EcoCyc10.6'/>
4.3 (calculated)
|-
|-
!align=left {{table heading style}} |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
||
||
2980 (calc based on 2 Y, 0 W, and 0 C residues)  
2,980 (calc based on 2 Y, 0 W, and 0 C residues)


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****************************************************************************************** -->{{Product_domains_motifs_help}}
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="N46ab0039a49ca"  class=" tableEdit Product_motif_table dataTable"   
|- {{table heading style}}
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!|Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References
|-
|
Modification Site
|
1
|
N-formylmethionine
|
[http://www.uniprot.org/uniprot/P68699#section_features UniProt:P68699]
|-  
|-  
|
|
Domain
Domain
|
|
10 - 32
8..77
|
|
Predicted membrane-spanning helix.
[http://pfam.janelia.org/family/PF00137 PF00137  ATP synthase subunit C]
|
|
TMD predicted by [http://www.cbs.dtu.dk/services/TMHMM TMHMM]<ref name='PMID:11152613' />
 
|-
|
|
Domain
PMID:19920124
|
53 - 75
|
Predicted membrane-spanning helix.
|
TMD predicted by [http://www.cbs.dtu.dk/services/TMHMM TMHMM]<ref name='PMID:11152613' />


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</table>


<span id="Structure"></span><big>'''Structure'''</big>
<table><tr valign='top'><td>
<span id='Structure'></span><big>'''Structure'''</big><br />
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|-
|-
!align=left {{table heading style}} |Structures
!align=left {{table heading style}} |Structures
||
||
<beststructure>atpE
<beststructure>
562</beststructure>
gene=atpE
 
taxon=562,83333
</beststructure>
|-
|-
!align=left {{table heading style}} |Models
!align=left {{table heading style}} |Models
||
||
View models at:
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=atpE&sub=keywordSearc EcoliPredict]
* [http://www.proteinmodelportal.org/query/uniprot/A5A609 Protein Model Portal]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=atpE&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P68699 PSI-PRED (P68699)]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P68699 Genomes TO Protein (P68699)] (GTOP)
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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<!--Structure_notes--></protect>
</td><td></protect>
==== Structure figures ====
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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===Notes===
===Notes===


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|- {{table_heading_style}}
|- {{table_heading_style}}
!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
|-  
|-  
|
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16131605 GI:16131605]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=ATPE-MONOMER EcoCyc:ATPE-MONOMER]
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
|
[http://www.ncbi.nlm.nih.gov/protein/NP_418193.1 GeneID:948253]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0012220
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P68699 UniProtKB/Swiss-Prot:P68699]
|
Escherichia coli str. K-12 substr. MG1655
|-  
|-  
|
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
[[EcoCyc]]
|
|
[[uniprot:P68699|UniProt:P68699]]
EcoCyc:EG10102
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
|
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
[[EcoGene]]
|
|
[http://pfam.sanger.ac.uk/family?acc=PF00137 PFAM:PF00137]
EcoGene:EG10102
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
|
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_418193 RefSeq:NP_418193]
[http://www.ncbi.nlm.nih.gov/gene?term=948253 GeneID:948253]
|
|
Escherichia coli str. K-12 substr. MG1655
|-  
|-  
|
|
[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
[[RegulonDB]]
|
|
[http://salilab.org/modbase/searchbyid?databaseID=P68699 ModBase:P68699]
RegulonDB:ECK120000098
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
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|
|
[http://www.rcsb.org/pdb PDB] ([[PDB|EcoliWiki Page]])
[[EchoBASE]]
|
|
[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1A91 PDB:1A91]
EchoBASE:EB0100
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]


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==References==
==References==
{{BacktoTop}}
{{BacktoTop}}
 
{{RefHelp}}
<references/>
<references />
__NOTOC__
__NOTOC__
</noinclude>
===Categories===
===Categories===
{{BacktoTop}}
{{BacktoTop}}
[[Category:Proteins]]
[[Category:Proteins]]
[[Category:GO:0016021_!_integral to membrane]][[Category:GO:0015986_!_ATP synthesis coupled proton transport]][[Category:GO:0016471_!_vacuolar proton-transporting V-type ATPase complex]][[Category:Complex:c subunit complex]][[Category:Complex:ATP synthase, F0 complex]][[Category:Complex:ATP synthase]][[Category:Location:plasma membrane]][[Category:Products with structures in PDB]]

Latest revision as of 21:07, 17 February 2015

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

AtpE

Synonyms

F0 sector of membrane-bound ATP synthase, subunit c[1], B3737[2][1], UncE[2][1], PapH[2][1], AtpE[2][1], dicyclohexylcarbodiimide-binding protein[2][1], lipid-binding protein[2][1], c chain[2][1] , ECK3730, JW3715, papH, uncE, b3737

Product description

ATP synthase, F0 complex, c subunit[2][3];

Component of c subunit complex[2][3]; ATP synthase, F0 complex[2][3]; ATP synthase[2][3]

ATP synthase subunit c, membrane-bound, F0 sector; DCCD-binding[4]

EC number (for enzymes)
edit table


Notes

Function

[back to top]


Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0016021

integral to membrane

PMID:2863271[5]

IDA: Inferred from Direct Assay

C

Seeded from Riley et al 2006 [1].

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0997

C

Seeded from EcoCyc (v14.0)

complete

Contributes to

GO:0046961

proton-transporting ATPase activity, rotational mechanism

PMID:2863271[5]

IMP: Inferred from Mutant Phenotype

F

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0045263

proton-transporting ATP synthase complex, coupling factor F(o)

PMID:6460031[6]

IMP: Inferred from Mutant Phenotype

C

complete

GO:0008289

lipid binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0446

F

Seeded from EcoCyc (v14.0)

complete

GO:0015078

hydrogen ion transmembrane transporter activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000454

F

Seeded from EcoCyc (v14.0)

complete

GO:0015078

hydrogen ion transmembrane transporter activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002379

F

Seeded from EcoCyc (v14.0)

complete

GO:0015078

hydrogen ion transmembrane transporter activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005953

F

Seeded from EcoCyc (v14.0)

complete

GO:0015986

ATP synthesis coupled proton transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000454

P

Seeded from EcoCyc (v14.0)

complete

GO:0015986

ATP synthesis coupled proton transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002379

P

Seeded from EcoCyc (v14.0)

complete

GO:0015986

ATP synthesis coupled proton transport

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005953

P

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9909

C

Seeded from EcoCyc (v14.0)

complete

GO:0045263

proton-transporting ATP synthase complex, coupling factor F(o)

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000454

C

Seeded from EcoCyc (v14.0)

complete

GO:0045263

proton-transporting ATP synthase complex, coupling factor F(o)

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005953

C

Seeded from EcoCyc (v14.0)

complete

GO:0045263

proton-transporting ATP synthase complex, coupling factor F(o)

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0138

C

Seeded from EcoCyc (v14.0)

complete

GO:0046933

hydrogen ion transporting ATP synthase activity, rotational mechanism

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01396

F

Seeded from EcoCyc (v14.0)

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of c subunit complex

could be indirect

Protein

Subunits of ATP synthase, F0 complex

could be indirect

Protein

Subunits of ATP synthase

could be indirect


edit table


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

plasma membrane

C-terminus localized to the periplasm with 2 predicted transmembrane domains

Daley et al. (2005) [7]

plasma membrane

From EcoCyc[3]

Inner Membrane

PMID:9237612[8]

EchoLocation:atpE


edit table


Notes

Structure and Physical Properties

[back to top]


Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MENLNMDLLY MAAAVMMGLA AIGAAIGIGI LGGKFLEGAA RQPDLIPLLR TQFFIVMGLV
DAIPMIAVGL GLYVMFAVA
Length

79

Mol. Wt

8.256 kDa

pI

4.3 (calculated)

Extinction coefficient

2,980 (calc based on 2 Y, 0 W, and 0 C residues)

edit table


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

8..77

PF00137 ATP synthase subunit C

PMID:19920124[9]

edit table

<motif_map/>

tmhmm.php?gene=atpE&show=pic&.jpg
Click the image to view raw output from TMHMM.

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=atpE taxon=562,83333 </beststructure>

Models

View models at:

edit table

Structure figures

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table


Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131605

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948253

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0012220

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P68699

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10102

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10102

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948253

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000098

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0100

Escherichia coli str. K-12 substr. MG1655

edit table


Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 3.2 3.3 3.4 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 Aris, JP et al. (1985) The Fo subunits of the Escherichia coli F1Fo-ATP synthase are sufficient to form a functional proton pore. J. Biol. Chem. 260 11207-15 PubMed
  6. ↑ Foster, DL & Fillingame, RH (1982) Stoichiometry of subunits in the H+-ATPase complex of Escherichia coli. J. Biol. Chem. 257 2009-15 PubMed
  7. ↑ Daley, DO et al. (2005) Global topology analysis of the Escherichia coli inner membrane proteome. Science 308 1321-3 PubMed
  8. ↑ Groth, G & Walker, JE (1997) Model of the c-subunit oligomer in the membrane domain of F-ATPases. FEBS Lett. 410 117-23 PubMed
  9. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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