moaE:Gene Product(s): Difference between revisions
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<noinclude>{{TabsTop}} | <noinclude>{{TabsTop}} | ||
{{Tab|Quickview|moaE}}{{Tab|Gene|moaE}}{{Tab On|Gene Product(s)|moaE}}{{Tab|Expression|moaE}}{{Tab|Evolution|moaE}}{{Tab|On One Page|moaE}}{{TabsBottom}} | {{Tab|Quickview|moaE}}{{Tab|Gene|moaE}}{{Tab On|Gene Product(s)|moaE}}{{Tab|Expression|moaE}}{{Tab|Evolution|moaE}}{{Tab|On One Page|moaE}}{{TabsBottom}} | ||
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|{{Sub}}[[#Localization |Localization]] | |{{Sub}}[[#Localization |Localization]] | ||
|{{Sub}}[[#Sequence|Sequence]] | |{{Sub}}[[#Sequence|Sequence]] | ||
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]] | |||
|{{Sub}}[[#Structure|Structure]] | |{{Sub}}[[#Structure|Structure]] | ||
|{{Sub}}[[#Gene Product Resources|Resources]] | |{{Sub}}[[#Gene Product Resources|Resources]] | ||
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==Nomenclature== | ==Nomenclature== | ||
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|- | |- | ||
!{{table heading style}} |Standard name | !align=left {{table heading style}} |Standard name | ||
| | || | ||
MoaE | MoaE | ||
|- | |- | ||
!{{table heading style}} |Synonyms | !align=left {{table heading style}} |Synonyms | ||
| | || | ||
molybdopterin synthase, large subunit<ref name='LIB:Riley_2006'/>, B0785<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MoaE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> | ''molybdopterin synthase, large subunit<ref name='LIB:Riley_2006'/>, B0785<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MoaE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0774, JW0768, b0785'' | ||
|- | |- | ||
!{{table heading style}} |Product description | !align=left {{table heading style}} |Product description | ||
| | || | ||
molybdopterin synthase large subunit<ref name='LIB:EcoCyc10.6'/> | molybdopterin synthase large subunit<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>; | ||
Component of [[:Category:Complex:molybdopterin synthase|molybdopterin synthase]]<ref name='LIB:EcoCyc11.1'/> | |||
Molybdopterin (MPT) synthase, large subunit; chlorate resistance; dimer of dimers with MoaD<ref name='LIB:EcoGene'/> | |||
|- | |- | ||
!{{table heading style}} |EC number (for enzymes) | !align=left {{table heading style}} |EC number (for enzymes) | ||
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===Notes=== | ===Notes=== | ||
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==Function== | ==Function== | ||
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<big>'''Gene Ontology'''</big><br /><!--box uid=421aa90e079fa326b6494f812ad13e79.21364.D46aa44200c78a--> | |||
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="D46aa44200c78a" class=" tableEdit GO_table_product dataTable" | |||
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!Qualifier!!GO ID!!GO term name!!Reference | !|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status | ||
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| | |||
| | |||
GO:0006777 | |||
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Mo-molybdopterin cofactor biosynthetic process | |||
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GOA:interpro<br />GO_REF:0000002 | |||
| | |||
IEA: Inferred from Electronic Annotation | |||
| | |||
InterPro:IPR003448 | |||
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P | |||
| | |||
Seeded from [[EcoCyc]] (v14.0) | |||
| | |||
complete | |||
|- | |||
| | | | ||
| | | | ||
GO:0006777 | GO:0006777 | ||
| | | | ||
Mo-molybdopterin cofactor biosynthetic process | Mo-molybdopterin cofactor biosynthetic process | ||
| | | | ||
GOA:spkw<br />SP_KW:GO_REF:0000004 | |||
| | | | ||
IEA: Inferred from Electronic Annotation | |||
| | | | ||
SP_KW:KW-0501 | |||
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P | P | ||
| | | | ||
Seeded from EcoCyc | Seeded from [[EcoCyc]] (v14.0) | ||
| | | | ||
complete | |||
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= | <span id="Interactions"></span><big>'''Interactions'''</big> | ||
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!Partner Type!!Partner!!Notes | !|Partner Type!!Partner!!Notes!!References!!Evidence | ||
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Protein | Protein | ||
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Subunits of [[:Category:Complex:molybdopterin synthase|molybdopterin synthase]] | Subunits of [[:Category:Complex:molybdopterin synthase|molybdopterin synthase]] | ||
| | | | ||
could be indirect | could be indirect | ||
|-class= | | | ||
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|- | |||
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Protein | |||
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moaD<br /> | |||
| | |||
| | |||
PMID:15690043 | |||
| | |||
Experiment(s):EBI-882423, EBI-889957<br /> | |||
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Protein | |||
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allR<br /> | |||
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| | |||
PMID:16606699 | |||
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Experiment(s):EBI-1137983<br /> | |||
|- | |||
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Protein | |||
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moaA<br /> | |||
| | |||
| | |||
PMID:16606699 | |||
| | |||
Experiment(s):EBI-1137983<br /> | |||
|- | |||
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Protein | |||
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gsiC<br /> | |||
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| | |||
PMID:16606699 | |||
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Experiment(s):EBI-1137983<br /> | |||
|- | |||
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Protein | |||
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ybiB<br /> | |||
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PMID:16606699 | |||
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Experiment(s):EBI-1137983<br /> | |||
|- | |||
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Protein | |||
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rpmB<br /> | |||
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PMID:16606699 | |||
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Experiment(s):EBI-1137983<br /> | |||
|- | |||
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Protein | |||
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glyQ<br /> | |||
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PMID:16606699 | |||
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Experiment(s):EBI-1137983<br /> | |||
|- | |||
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Protein | |||
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fdoG<br /> | |||
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PMID:16606699 | |||
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Experiment(s):EBI-1137983<br /> | |||
|- | |||
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Protein | |||
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nadE<br /> | |||
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PMID:16606699 | |||
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Experiment(s):EBI-1137983<br /> | |||
|- | |||
| | |||
Protein | |||
| | |||
moaD | |||
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PMID:19402753 | |||
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LCMS(ID Probability):99.6 MALDI(Z-score):11.288472 | |||
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===Notes=== | ===Notes=== | ||
==Localization== | ==Localization== | ||
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!|Compartment!!Description!!Evidence!!Reference/Source!!Notes | |||
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<protect><!--Localization_notes--></protect> | <protect><!--Localization_notes--></protect> | ||
===Notes=== | ===Notes=== | ||
==Structure and Physical Properties== | ==Structure and Physical Properties== | ||
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<protect> | <protect> | ||
= | <span id="Sequence"></span><big>'''Physical Properties'''</big> | ||
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!align=left {{table heading style}} |Name | |||
|| | |||
|- | |- | ||
!{{table heading style}} |Sequence | !align=left {{table heading style}} |Sequence | ||
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[http://biocyc.org/ECOLI/sequence-aa?object=EG11598-MONOMER at EcoCyc] | [http://biocyc.org/ECOLI/sequence-aa?object=EG11598-MONOMER at EcoCyc] | ||
<pre>MAETKIVVGP QPFSVGEEYP WLAERDEDGA VVTFTGKVRN HNLGDSVNAL TLEHYPGMTE | <pre>MAETKIVVGP QPFSVGEEYP WLAERDEDGA VVTFTGKVRN HNLGDSVNAL TLEHYPGMTE | ||
| Line 119: | Line 313: | ||
RAPFWKREAT PEGDRWVEAR ESDQQAAKRW</pre> | RAPFWKREAT PEGDRWVEAR ESDQQAAKRW</pre> | ||
|- | |- | ||
!{{table heading style}} | | !align=left {{table heading style}} |Length | ||
| | || | ||
150 | |||
|- | |- | ||
!{{table heading style}} | | !align=left {{table heading style}} |Mol. Wt | ||
| | || | ||
16.98 kDa | |||
|- | |- | ||
!{{table heading style}} | | !align=left {{table heading style}} |pI | ||
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5.2 (calculated) | |||
|- | |- | ||
| | !align=left {{table heading style}} |Extinction coefficient | ||
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37,470 (calc based on 3 Y, 6 W, and 0 C residues) | |||
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= | |||
<!--box uid=421aa90e079fa326b6494f812ad13e79.. | <span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span><table> | ||
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!Type!!Residues!!Description!!Notes | !|Type!!Residues!!Description!!Notes!!References | ||
|- | |- | ||
| | | | ||
| | Initiator Methionine | ||
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1 | |||
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Removed | |||
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[http://www.uniprot.org/uniprot/P30749#section_features UniProt:P30749] | |||
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|- | |||
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Domain | |||
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5..122 | |||
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[http:// | [http://pfam.janelia.org/family/PF02391 PF02391 MoaE protein] | ||
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PMID:19920124 | |||
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<span id='Structure'></span><big>'''Structure'''</big><br /> | |||
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!align=left {{table heading style}} |Structures | |||
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<beststructure> | |||
gene=moaE | |||
taxon=562,83333 | |||
</beststructure> | |||
|- | |||
!align=left {{table heading style}} |Models | |||
|| | |||
View models at: | |||
* [http://www.proteinmodelportal.org/query/uniprot/P30749 Protein Model Portal] | |||
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P30749 PSI-PRED (P30749)] | |||
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P30749 Genomes TO Protein (P30749)] (GTOP) | |||
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==== Structure figures ==== | |||
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===Notes=== | ===Notes=== | ||
==Gene Product Resources== | ==Gene Product Resources== | ||
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!Resource type!!Source!!Notes/Reference | !|Resource type!!Source!!Notes/Reference | ||
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===Notes=== | ===Notes=== | ||
==Accessions in Other Databases== | ==Accessions in Other Databases== | ||
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!Database!!Accession!!Notes | !|Database!!Accession!!Notes | ||
|- | |- | ||
| | |||
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]]) | |||
| | |||
[http://www.ncbi.nlm.nih.gov/protein/16128753 GI:16128753] | |||
| | |||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |||
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[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]]) | |||
| | |||
[http://www.ncbi.nlm.nih.gov/protein/NP_415306.1 GeneID:945399] | |||
| | |||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |||
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[[ASAP]] | |||
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ASAP:ABE-0002678 | |||
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |||
| | | | ||
[http:// | [http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]]) | ||
| | | | ||
[http:// | [http://www.uniprot.org/uniprot/P30749 UniProtKB/Swiss-Prot:P30749] | ||
| | | | ||
Escherichia coli str. K-12 substr. MG1655 | |||
|- | |- | ||
| | | | ||
[[EcoCyc]] | |||
| | | | ||
EcoCyc:EG11598 | |||
| | | | ||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |- | ||
| | | | ||
[[EcoGene]] | |||
| | | | ||
EcoGene:EG11598 | |||
| | | | ||
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
|- | |- | ||
| | | | ||
[http://www.ncbi.nlm.nih.gov/ | [http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]]) | ||
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[http://www.ncbi.nlm.nih.gov/ | [http://www.ncbi.nlm.nih.gov/gene?term=945399 GeneID:945399] | ||
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Escherichia coli str. K-12 substr. MG1655 | |||
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[[RegulonDB]] | |||
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RegulonDB:ECK120001546 | |||
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
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[[EchoBASE]] | |||
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EchoBASE:EB1555 | |||
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]] | |||
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[[Category: | ===Categories=== | ||
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[[Category:Proteins]] | |||
Latest revision as of 20:30, 17 February 2015
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
MoaE |
|---|---|
| Synonyms |
molybdopterin synthase, large subunit[1], B0785[2][1], MoaE[2][1] , ECK0774, JW0768, b0785 |
| Product description |
molybdopterin synthase large subunit[2][3]; Component of molybdopterin synthase[3] Molybdopterin (MPT) synthase, large subunit; chlorate resistance; dimer of dimers with MoaD[4] |
| EC number (for enzymes) |
|
| edit table |
Notes
Function
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0006777 |
Mo-molybdopterin cofactor biosynthetic process |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006777 |
Mo-molybdopterin cofactor biosynthetic process |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of molybdopterin synthase |
could be indirect |
||
|
Protein |
moaD |
Experiment(s):EBI-882423, EBI-889957 | ||
|
Protein |
allR |
Experiment(s):EBI-1137983 | ||
|
Protein |
moaA |
Experiment(s):EBI-1137983 | ||
|
Protein |
gsiC |
Experiment(s):EBI-1137983 | ||
|
Protein |
ybiB |
Experiment(s):EBI-1137983 | ||
|
Protein |
rpmB |
Experiment(s):EBI-1137983 | ||
|
Protein |
glyQ |
Experiment(s):EBI-1137983 | ||
|
Protein |
fdoG |
Experiment(s):EBI-1137983 | ||
|
Protein |
nadE |
Experiment(s):EBI-1137983 | ||
|
Protein |
moaD |
LCMS(ID Probability):99.6 MALDI(Z-score):11.288472 | ||
| edit table |
Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
Notes
Structure and Physical Properties
Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MAETKIVVGP QPFSVGEEYP WLAERDEDGA VVTFTGKVRN HNLGDSVNAL TLEHYPGMTE KALAEIVDEA RNRWPLGRVT VIHRIGELWP GDEIVFVGVT SAHRSSAFEA GQFIMDYLKT RAPFWKREAT PEGDRWVEAR ESDQQAAKRW |
| Length |
150 |
| Mol. Wt |
16.98 kDa |
| pI |
5.2 (calculated) |
| Extinction coefficient |
37,470 (calc based on 3 Y, 6 W, and 0 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
|
Structure figures
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
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