moaE:Gene Product(s): Difference between revisions

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<noinclude>{{TabsTop}}
<noinclude>{{TabsTop}}
{{Tab|Quickview|moaE}}{{Tab|Gene|moaE}}{{Tab On|Gene Product(s)|moaE}}{{Tab|Expression|moaE}}{{Tab|Evolution|moaE}}{{Tab|On One Page|moaE}}{{TabsBottom}}
{{Tab|Quickview|moaE}}{{Tab|Gene|moaE}}{{Tab On|Gene Product(s)|moaE}}{{Tab|Expression|moaE}}{{Tab|Evolution|moaE}}{{Tab|On One Page|moaE}}{{TabsBottom}}
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|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Localization |Localization]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Sequence|Sequence]]
|{{Sub}}[[#Domains/Motifs/Modification Sites|Domains]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Structure|Structure]]
|{{Sub}}[[#Gene Product Resources|Resources]]
|{{Sub}}[[#Gene Product Resources|Resources]]
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==Nomenclature==
==Nomenclature==
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|-
|-
!{{table heading style}} |Standard name
!align=left {{table heading style}} |Standard name
|
||
MoaE product
MoaE  
|-
|-
!{{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
|
||
molybdopterin synthase, large subunit<ref name='LIB:Riley_2006'/>, B0785<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MoaE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''molybdopterin synthase, large subunit<ref name='LIB:Riley_2006'/>, B0785<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, MoaE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0774, JW0768, b0785''
|-
|-
!{{table heading style}} |Product description
!align=left {{table heading style}} |Product description
|
||
molybdopterin synthase large subunit<ref name='LIB:EcoCyc10.6'/>; molybdopterin synthase large subunit<ref name='LIB:EcoCyc11.1'/>; Component of [[:Category:Complex:molybdopterin synthase|molybdopterin synthase]]<ref name='LIB:EcoCyc11.1'/>; molybdopterin synthase<ref name='LIB:EcoCyc11.1'/>
molybdopterin synthase large subunit<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;  
 
Component of [[:Category:Complex:molybdopterin synthase|molybdopterin synthase]]<ref name='LIB:EcoCyc11.1'/>


Molybdopterin (MPT) synthase, large subunit; chlorate resistance; dimer of dimers with MoaD<ref name='LIB:EcoGene'/>
|-
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!{{table heading style}} |EC number (for enzymes)
!align=left {{table heading style}} |EC number (for enzymes)
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*
 
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===Notes===
===Notes===
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==Function==
==Function==
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===Gene Ontology===
<big>'''Gene Ontology'''</big><br /><!--box uid=421aa90e079fa326b6494f812ad13e79.21364.D46aa44200c78a-->
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!Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-
|-
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|
GO:0006777
|
Mo-molybdopterin cofactor biosynthetic process
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR003448
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-  
|
|
 
|
|
GO:0006777  
GO:0006777
|
|
Mo-molybdopterin cofactor biosynthetic process  
Mo-molybdopterin cofactor biosynthetic process
|
|
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IEA: Inferred from Electronic Annotation
|
|
SP_KW:KW-0501
|
|
P  
P
|
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.  
Seeded from [[EcoCyc]] (v14.0)
|
|
required fields missing 
complete
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===Interactions===
<span id="Interactions"></span><big>'''Interactions'''</big>
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!Partner Type!!Partner!!Notes
!|Partner Type!!Partner!!Notes!!References!!Evidence
|-
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Protein
Protein
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Subunits of [[:Category:Complex:molybdopterin synthase|molybdopterin synthase]]  
Subunits of [[:Category:Complex:molybdopterin synthase|molybdopterin synthase]]  
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could be indirect   
could be indirect  
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|
   
|-
|
Protein
|
moaD<br />
|
 
|
PMID:15690043
|
Experiment(s):EBI-882423, EBI-889957<br />
|-
|
Protein
|
allR<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137983<br />
|-
|
Protein
|
moaA<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137983<br />
|-
|
Protein
|
gsiC<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137983<br />
|-
|
Protein
|
ybiB<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137983<br />
|-
|
Protein
|
rpmB<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137983<br />
|-
|
Protein
|
glyQ<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137983<br />
|-
|
Protein
|
fdoG<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137983<br />
|-
|
Protein
|
nadE<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137983<br />
|-
|
Protein
|
moaD
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.6 MALDI(Z-score):11.288472
 
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<!--Function_notes--></protect>
<!--Function_notes--></protect>
===Notes===
===Notes===


==Localization==
==Localization==
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!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
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<protect><!--Localization_notes--></protect>
<protect><!--Localization_notes--></protect>
===Notes===
===Notes===


==Structure and Physical Properties==
==Structure and Physical Properties==
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===Physical Properties===
<span id="Sequence"></span><big>'''Physical Properties'''</big>
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|-
!align=left {{table heading style}} |Name
||
 
|-
|-
!{{table heading style}} |Sequence
!align=left {{table heading style}} |Sequence
|
||
[http://biocyc.org/ECOLI/sequence-aa?object=EG11598-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=EG11598-MONOMER at EcoCyc]  
<pre>MAETKIVVGP QPFSVGEEYP WLAERDEDGA VVTFTGKVRN HNLGDSVNAL TLEHYPGMTE
<pre>MAETKIVVGP QPFSVGEEYP WLAERDEDGA VVTFTGKVRN HNLGDSVNAL TLEHYPGMTE
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RAPFWKREAT PEGDRWVEAR ESDQQAAKRW</pre>  
RAPFWKREAT PEGDRWVEAR ESDQQAAKRW</pre>  
|-
|-
!{{table heading style}} |Mol. Wt
!align=left {{table heading style}} |Length
|
||
16.98 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
150
|-
|-
!{{table heading style}} |pI
!align=left {{table heading style}} |Mol. Wt
|
||
16.98 kDa
|-
|-
!{{table heading style}} |Extinction coefficient
!align=left {{table heading style}} |pI
|
||
37470 (calc based on 3 Y, 6 W, and 0 C residues)  
5.2 (calculated)
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!align=left {{table heading style}} |Extinction coefficient
||
37,470 (calc based on 3 Y, 6 W, and 0 C residues)
 
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===Domains/Motifs/Modification Sites===
 
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<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span><table>
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!Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References
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Initiator Methionine
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1
===Structure===
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Removed
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{|class = 'sortable' {{Prettytable}} id='37097'
[http://www.uniprot.org/uniprot/P30749#section_features UniProt:P30749]
|- {{table heading style}}
!Structure Type!!Organism!!Accession!!Residues covered!!Notes
|-
|
|
X-RAY DIFFRACTION
   
   
|-
|
|
Escherichia coli
Domain
|
5..122
|
|
[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1NVI 1NVI] Orthorhombic Crystal Form of Molybdopterin Synthase
[http://pfam.janelia.org/family/PF02391 PF02391  MoaE protein]
|
|
|
PMID:19920124
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<!-- motifs column 2-->
   
   
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<motif_map/>
 
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<table><tr valign='top'><td>
<span id='Structure'></span><big>'''Structure'''</big><br />
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!align=left {{table heading style}} |Structures
||
<beststructure>
gene=moaE
taxon=562,83333
</beststructure>
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!align=left {{table heading style}} |Models
||
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P30749 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P30749 PSI-PRED (P30749)]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P30749 Genomes TO Protein (P30749)] (GTOP)
 
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<!--Structure_notes--></protect>
</td><td></protect>
==== Structure figures ====
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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===Notes===
===Notes===




==Gene Product Resources==
==Gene Product Resources==
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!|Resource type!!Source!!Notes/Reference
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===Notes===
===Notes===


==Accessions in Other Databases==
==Accessions in Other Databases==
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|- {{table_heading_style}}
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!Database!!Accession!!Notes
!|Database!!Accession!!Notes
|-
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16128753 GI:16128753]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_415306.1 GeneID:945399]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0002678
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
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[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11598-MONOMER EcoCyc:EG11598-MONOMER]
[http://www.uniprot.org/uniprot/P30749 UniProtKB/Swiss-Prot:P30749]
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Escherichia coli str. K-12 substr. MG1655
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[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
[[EcoCyc]]
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[http://www.expasy.ch/cgi-bin/sprot-search-ac?P30749 UniProt:P30749] 
EcoCyc:EG11598
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://www.sanger.ac.uk/Software/Pfam/ PFAM] ([[PFAM|EcoliWiki Page]])
[[EcoGene]]
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[http://www.sanger.ac.uk/cgi-bin/Pfam/getacc?PF02391 PFAM:PF02391] 
EcoGene:EG11598
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
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[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415306 RefSeq:NP_415306]
[http://www.ncbi.nlm.nih.gov/gene?term=945399 GeneID:945399]
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Escherichia coli str. K-12 substr. MG1655
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[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
[[RegulonDB]]
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[http://salilab.org/modbase/searchbyid?databaseID=P30749 ModBase:P30749] 
RegulonDB:ECK120001546
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://www.rcsb.org/pdb PDB] ([[PDB|EcoliWiki Page]])
[[EchoBASE]]
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[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1NVI PDB:1NVI] 
EchoBASE:EB1555
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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===Notes===
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==Links==
==Links==
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<noinclude>
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==References==
==References==
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<references />
__NOTOC__
__NOTOC__
[[Category:GO:0006777]][[Category:Complex:molybdopterin synthase]]</noinclude>
===Categories===
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[[Category:Proteins]]

Latest revision as of 20:30, 17 February 2015

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MoaE

Synonyms

molybdopterin synthase, large subunit[1], B0785[2][1], MoaE[2][1] , ECK0774, JW0768, b0785

Product description

molybdopterin synthase large subunit[2][3];

Component of molybdopterin synthase[3]

Molybdopterin (MPT) synthase, large subunit; chlorate resistance; dimer of dimers with MoaD[4]

EC number (for enzymes)



Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003448

P

Seeded from EcoCyc (v14.0)

complete

GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0501

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of molybdopterin synthase

could be indirect

Protein

moaD

PMID:15690043[5]

Experiment(s):EBI-882423, EBI-889957

Protein

allR

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

moaA

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

gsiC

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

ybiB

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

rpmB

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

glyQ

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

fdoG

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

nadE

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

moaD

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):11.288472


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes


Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MAETKIVVGP QPFSVGEEYP WLAERDEDGA VVTFTGKVRN HNLGDSVNAL TLEHYPGMTE
KALAEIVDEA RNRWPLGRVT VIHRIGELWP GDEIVFVGVT SAHRSSAFEA GQFIMDYLKT
RAPFWKREAT PEGDRWVEAR ESDQQAAKRW
Length

150

Mol. Wt

16.98 kDa

pI

5.2 (calculated)

Extinction coefficient

37,470 (calc based on 3 Y, 6 W, and 0 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P30749

Domain

5..122

PF02391 MoaE protein

PMID:19920124[8]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=moaE taxon=562,83333 </beststructure>

Models

View models at:

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference


Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128753

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945399

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0002678

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P30749

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11598

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11598

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945399

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001546

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1555

Escherichia coli str. K-12 substr. MG1655


Notes

Links

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References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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