moaE:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

MoaE

Synonyms

molybdopterin synthase, large subunit[1], B0785[2][1], MoaE[2][1] , ECK0774, JW0768, b0785

Product description

molybdopterin synthase large subunit[2][3];

Component of molybdopterin synthase[3]

Molybdopterin (MPT) synthase, large subunit; chlorate resistance; dimer of dimers with MoaD[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR003448

P

Seeded from EcoCyc (v14.0)

complete

GO:0006777

Mo-molybdopterin cofactor biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0501

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of molybdopterin synthase

could be indirect

Protein

moaD

PMID:15690043[5]

Experiment(s):EBI-882423, EBI-889957

Protein

allR

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

moaA

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

gsiC

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

ybiB

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

rpmB

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

glyQ

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

fdoG

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

nadE

PMID:16606699[6]

Experiment(s):EBI-1137983

Protein

moaD

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):11.288472

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MAETKIVVGP QPFSVGEEYP WLAERDEDGA VVTFTGKVRN HNLGDSVNAL TLEHYPGMTE
KALAEIVDEA RNRWPLGRVT VIHRIGELWP GDEIVFVGVT SAHRSSAFEA GQFIMDYLKT
RAPFWKREAT PEGDRWVEAR ESDQQAAKRW
Length

150

Mol. Wt

16.98 kDa

pI

5.2 (calculated)

Extinction coefficient

37,470 (calc based on 3 Y, 6 W, and 0 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P30749

Domain

5..122

PF02391 MoaE protein

PMID:19920124[8]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=moaE taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128753

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945399

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0002678

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P30749

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11598

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11598

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945399

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001546

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1555

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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