flgE:Gene Product(s): Difference between revisions

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!align=left {{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
||
||
flagellar hook protein<ref name='LIB:Riley_2006'/>, B1076<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Fla<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FlaK<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FlgE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''flagellar hook protein<ref name='LIB:Riley_2006'/>, B1076<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, Fla<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FlaK<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, FlgE<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK1061, flaK, JW1063, b1076''
|-
|-
!align=left {{table heading style}} |Product description
!align=left {{table heading style}} |Product description
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{|   id="T46aa54e1c6673"  class=" tableEdit GO_table_product dataTable"   
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="T46aa54e1c6673"  class=" tableEdit GO_table_product dataTable"   
|- {{table_heading_style}}
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-  
|-  
|
|


|
|
GO:0030694
GO:0001539
|
|
flagellin-based flagellum basal body, rod
ciliary or flagellar motility
|
|
GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR011491
InterPro:IPR001444
|
|
C
P
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0019861
GO:0001539
|
|
flagellum
ciliary or flagellar motility
|
|
GO_REF:0000002<br />GO_REF:0000004
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR010930<br />SP_KW:KW-0282
InterPro:IPR019776
|
|
C
P
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0009288
GO:0003774
|
|
bacterial-type flagellum
motor activity
|
|
GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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InterPro:IPR001444
InterPro:IPR001444
|
|
C
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0003774
|
motor activity
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR019776
|
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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structural molecule activity
structural molecule activity
|
|
GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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F
F
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0003774
GO:0005198
|
|
motor activity
structural molecule activity
|
|
GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR001444
InterPro:IPR019776
|
|
F
F
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0001539
GO:0009288
|
|
ciliary or flagellar motility
bacterial-type flagellum
|
|
GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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InterPro:IPR001444
InterPro:IPR001444
|
|
P
C
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
GO:0005515
GO:0009288
|
|
protein binding
bacterial-type flagellum
|
|
PMID:16606699
GOA:interpro<br />GO_REF:0000002
|
|
IPI: Inferred from Physical Interaction
IEA: Inferred from Electronic Annotation
|
|
UniProtKB:P18843
InterPro:IPR019776
|
|
F
C
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
|-  
|-  
|
|
 
|
|
GO:0009296
GO:0009288
|
|
flagellum biogenesis
bacterial-type flagellum
|
|
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IEA: Inferred from Electronic Annotation
|
|
SP_KW:KW-0975
|
|
P
C
|
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.  
Seeded from [[EcoCyc]] (v14.0)
|
|
required fields missing 
complete
|-  
|-  
|
|


|
|
GO:0009425
GO:0009424
|
|
bacterial-type flagellum basal body
bacterial-type flagellum hook
|
|
GO_REF:0000023
PMID:338588
|
|
IEA: Inferred from Electronic Annotation
IMP: Inferred from Mutant Phenotype
|
|
SP_SL:SL-0142
 
|
|
C
C
|
|
Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
 
|
|
complete  
complete  
|-  
|-  
|
|
 
|
|
GO:0042330
GO:0009425
|
|
taxis
bacterial-type flagellum basal body
|
|
GO_REF:0000023
|
|
IEA: Inferred from Electronic Annotation
|
|
SP_SL:SL-0142
|
|
P
C
|
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.  
Seeded from [[EcoCyc]] (v14.0)
|
|
required fields missing 
complete
|-  
|-  
|
|
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bacterial-type flagellum hook
bacterial-type flagellum hook
|
|
PMID:338588
PMID:6374380
|
|
IMP: Inferred from Mutant Phenotype
IMP: Inferred from Mutant Phenotype
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|
|
GO:0009424
GO:0019861
|
flagellum
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR010930
|
|
bacterial-type flagellum hook
C
|
|
PMID:6374380
Seeded from [[EcoCyc]] (v14.0)
|
|
IMP: Inferred from Mutant Phenotype
complete
|-
|
|


|
GO:0030694
|
bacterial-type flagellum basal body, rod
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR011491
|
|
C
C
|
|
 
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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{|   id="E46aa54ee367aa"  class=" tableEdit Product_interactions_table dataTable"   
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="E46aa54ee367aa"  class=" tableEdit Product_interactions_table dataTable"   
|- {{table heading style}}
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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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{|   id="G46a7e774acc62"  class=" tableEdit Product_localization_table"   
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="G46a7e774acc62"  class=" tableEdit Product_localization_table"   
|- {{table heading style}}
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!|Compartment!!Description!!Evidence!!Source!!Notes
!|Compartment!!Description!!Evidence!!Reference/Source!!Notes


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!align=left {{table heading style}} |Name
||


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!align=left {{table heading style}} |Extinction coefficient
!align=left {{table heading style}} |Extinction coefficient
||
||
25,900 (calc based on 10 Y, 2 W, and C residues)
25,900 (calc based on 10 Y, 2 W, and 0 C residues)


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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="L46aa54f0b485b"  class=" tableEdit Product_motif_table dataTable"   
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!|Type!!Residues!!Description!!Notes!!References
!|Type!!Residues!!Description!!Notes!!References
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|
|
   
   
|-
|
Domain
|
3..33
|
[http://pfam.janelia.org/family/PF00460 PF00460  Flagella basal body rod protein]
|
|
PMID:19920124
|-
|
Domain
|
363..401
|
[http://pfam.janelia.org/family/PF06429 PF06429  Domain of unknown function (DUF1078)]
|
|
PMID:19920124
|-
|
Domain
|
170..283
|
[http://pfam.janelia.org/family/PF07559 PF07559  Flagellar basal body protein FlaE]
|
|
PMID:19920124


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||
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View models at:
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://www.proteinmodelportal.org/query/uniprot/P75937 Protein Model Portal]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P75937 PSI-PRED (P75937)]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P75937 Genomes TO Protein (P75937)] (GTOP)
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="D46aa54f15ae1a"  class=" tableEdit Product_resource_table"   
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!|Resource type!!Source!!Notes/Reference
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{|   id="U46aa54f1a7c77"  class=" tableEdit Gene_accessions_table"   
{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="U46aa54f1a7c77"  class=" tableEdit Gene_accessions_table"   
|- {{table_heading_style}}
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!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
|-  
|-  
|
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16129039 GI:16129039]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_415594.1 GeneID:945636]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=G361-MONOMER EcoCyc:G361-MONOMER]
ASAP:ABE-0003647
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
[http://www.uniprot.org/uniprot/P75937 UniProtKB/Swiss-Prot:P75937]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[EcoCyc]]
|
EcoCyc:G361
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
|
|
[http://swissmodel.expasy.org/repository/ SwissModel] ([[SwissModel|EcoliWiki Page]])
[[EcoGene]]
|
|
[http://swissmodel.expasy.org/repository/smr.php?job=2&sptr_ac=P75937 SwissModel:P75937]
EcoGene:EG14269
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
|
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
|
[[uniprot:P75937|UniProt:P75937]]
[http://www.ncbi.nlm.nih.gov/gene?term=945636 GeneID:945636]
|
|
Escherichia coli str. K-12 substr. MG1655
|-  
|-  
|
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
[[RegulonDB]]
|
|
[http://pfam.sanger.ac.uk/family?acc=PF00460 PFAM:PF00460]
RegulonDB:ECK120002683
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|-  
|
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
[[EchoBASE]]
|
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415594 RefSeq:NP_415594]
EchoBASE:EB4017
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]


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{{BacktoTop}}
{{BacktoTop}}
[[Category:Proteins]]
[[Category:Proteins]]
[[Category:GO:0009296_!_flagellum biogenesis]][[Category:GO:0042330_!_taxis]][[Category:GO:0019861_!_flagellum]][[Category:Complex:Flagellum]]

Latest revision as of 20:34, 17 February 2015

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

FlgE

Synonyms

flagellar hook protein[1], B1076[2][1], Fla[2][1], FlaK[2][1], FlgE[2][1] , ECK1061, flaK, JW1063, b1076

Product description

flagellar hook protein FlgE[2][3];

Component of Flagellum[3]

Flagellar hook subunit protein[4]

EC number (for enzymes)


edit table


Notes

Function

[back to top]


Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001539

ciliary or flagellar motility

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

P

Seeded from EcoCyc (v14.0)

complete

GO:0001539

ciliary or flagellar motility

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019776

P

Seeded from EcoCyc (v14.0)

complete

GO:0003774

motor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

F

Seeded from EcoCyc (v14.0)

complete

GO:0003774

motor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019776

F

Seeded from EcoCyc (v14.0)

complete

GO:0005198

structural molecule activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

F

Seeded from EcoCyc (v14.0)

complete

GO:0005198

structural molecule activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019776

F

Seeded from EcoCyc (v14.0)

complete

GO:0009288

bacterial-type flagellum

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001444

C

Seeded from EcoCyc (v14.0)

complete

GO:0009288

bacterial-type flagellum

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019776

C

Seeded from EcoCyc (v14.0)

complete

GO:0009288

bacterial-type flagellum

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0975

C

Seeded from EcoCyc (v14.0)

complete

GO:0009424

bacterial-type flagellum hook

PMID:338588[5]

IMP: Inferred from Mutant Phenotype

C

complete

GO:0009425

bacterial-type flagellum basal body

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0142

C

Seeded from EcoCyc (v14.0)

complete

GO:0009424

bacterial-type flagellum hook

PMID:6374380[6]

IMP: Inferred from Mutant Phenotype

C

complete

GO:0019861

flagellum

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010930

C

Seeded from EcoCyc (v14.0)

complete

GO:0030694

bacterial-type flagellum basal body, rod

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011491

C

Seeded from EcoCyc (v14.0)

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of Flagellum

could be indirect

Protein

nadE

PMID:16606699[7]

Experiment(s):EBI-1138775
edit table


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
edit table


Notes

Structure and Physical Properties

[back to top]


Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MAFSQAVSGL NAAATNLDVI GNNIANSATY GFKSGTASFA DMFAGSKVGL GVKVAGITQD
FTDGTTTNTG RGLDVAISQN GFFRLVDSNG SVFYSRNGQF KLDENRNLVN MQGLQLTGYP
ATGTPPTIQQ GANPTNISIP NTLMAAKTTT TASMQINLNS SDPLPTVTPF SASNADSYNK
KGSVTVFDSQ GNAHDMSVYF VKTGDNNWQV YTQDSSDPNS IAKTATTLEF NANGTLVDGA
MANNIATGAI NGAEPATFSL SFLNSMQQNT GANNIVATTQ NGYKPGDLVS YQINDDGTVV
GNYSNEQTQL LGQIVLANFA NNEGLASEGD NVWSATQSSG VALLGTAGTG NFGTLTNGAL
EASNVDLSKE LVNMIVAQRN YQSNAQTIKT QDQILNTLVN LR
Length

402

Mol. Wt

42.044 kDa

pI

4.3 (calculated)

Extinction coefficient

25,900 (calc based on 10 Y, 2 W, and 0 C residues)

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Domains/Motifs/Modification Sites

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Type Residues Description Notes References

Initiator Methionine

1

Removed (By similarity)

UniProt:P75937

Domain

3..33

PF00460 Flagella basal body rod protein

PMID:19920124[8]

Domain

363..401

PF06429 Domain of unknown function (DUF1078)

PMID:19920124[8]

Domain

170..283

PF07559 Flagellar basal body protein FlaE

PMID:19920124[8]

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<motif_map/>

Structure
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Structures

<beststructure> gene=flgE taxon=562,83333 </beststructure>

Models

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Structure figures

Notes

Gene Product Resources

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Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129039

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945636

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003647

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P75937

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G361

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG14269

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945636

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002683

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB4017

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Komeda, Y et al. (1978) Identification of the structural gene for the hook subunit protein of Escherichia coli flagella. J. Bacteriol. 133 364-71 PubMed
  6. ↑ Komeda, Y et al. (1984) Synthesis of flagellin and hook subunit protein in flagellar mutants of Escherichia coli K12. Mol. Gen. Genet. 194 49-51 PubMed
  7. ↑ Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  8. ↑ 8.0 8.1 8.2 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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