parC:Gene Product(s): Difference between revisions

Standard name	ParC
Synonyms	DNA topoisomerase IV, subunit A^[1], B3019^[2]^[1], ParC^[2]^[1] , ECK3010, JW2987, b3019 Category:Complex:topoisomerase IV
Product description	topoisomerase IV subunit A^[2]^[3]; Component of Topoisomerase IV^[3] Topoisomerase IV, subunit A, ATP-dependent, type II; chromosome decatenase; relaxes both positive and negative supercoils; DNA unknotting activity; heterotetrameric^[4]
EC number (for enzymes)	5.99.1.-^[1]
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Notes

More information about the Topo IV complex may be found on the Topoisomerase IV page.

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0003918	DNA topoisomerase (ATP-hydrolyzing) activity		IDA: Inferred from Direct Assay		F		Missing: reference
	GO:0007059	chromosome segregation	PMID:2842295^[5]	IMP: Inferred from Mutant Phenotype		P		complete
	GO:0003677	DNA binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002205	F	Seeded from EcoCyc (v14.0)	complete
Contributes to	GO:0003916	DNA topoisomerase activity	PMID:1334483^[6]	IDA: Inferred from Direct Assay		F		complete
	GO:0003677	DNA binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR005742	F	Seeded from EcoCyc (v14.0)	complete
	GO:0019897	extrinsic to plasma membrane	PMID:1334483^[6]	IDA: Inferred from Direct Assay		C	in the presence of DNA	complete
	GO:0003677	DNA binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006691	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005737	cytoplasm	PMID:1334483^[6]	IDA: Inferred from Direct Assay		C	in the presence of Mg2+	complete
	GO:0003677	DNA binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013757	F	Seeded from EcoCyc (v14.0)	complete
Contributes to	GO:0003918	DNA topoisomerase (ATP-hydrolyzing) activity	PMID:8227000^[7]	IDA: Inferred from Direct Assay		F		complete
	GO:0003677	DNA binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013758	F	Seeded from EcoCyc (v14.0)	complete
	GO:0009330	DNA topoisomerase complex (ATP-hydrolyzing)	PMID:8227000^[7]	IDA: Inferred from Direct Assay		C		complete
	GO:0006265	DNA topological change	PMID:8227000^[7]	IDA: Inferred from Direct Assay		P		complete
	GO:0003677	DNA binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013760	F	Seeded from EcoCyc (v14.0)	complete
	GO:0003677	DNA binding	PMID:16023670^[8]	IDA: Inferred from Direct Assay		F		complete
	GO:0003677	DNA binding	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0238	F	Seeded from EcoCyc (v14.0)	complete
	GO:0003916	DNA topoisomerase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006691	F	Seeded from EcoCyc (v14.0)	complete
	GO:0030541	plasmid partitioning	PMID:8104339^[9]	IDA: Inferred from Direct Assay		P		complete
	GO:0003916	DNA topoisomerase activity	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0799	F	Seeded from EcoCyc (v14.0)	complete
	GO:0003918	DNA topoisomerase (ATP-hydrolyzing) activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002205	F	Seeded from EcoCyc (v14.0)	complete
	GO:0003918	DNA topoisomerase (ATP-hydrolyzing) activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR005742	F	Seeded from EcoCyc (v14.0)	complete
	GO:0003918	DNA topoisomerase (ATP-hydrolyzing) activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013757	F	Seeded from EcoCyc (v14.0)	complete
	GO:0006265	DNA topological change	PMID:16023670^[8]	IDA: Inferred from Direct Assay		P		complete
	GO:0003918	DNA topoisomerase (ATP-hydrolyzing) activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013758	F	Seeded from EcoCyc (v14.0)	complete
	GO:0007059	chromosome segregation	PMID:16023670^[8]	IDA: Inferred from Direct Assay		P		complete
	GO:0003918	DNA topoisomerase (ATP-hydrolyzing) activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013760	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002205	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR005742	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006691	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013757	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013758	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013760	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005694	chromosome	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002205	C	Seeded from EcoCyc (v14.0)	complete
	GO:0005694	chromosome	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR005742	C	Seeded from EcoCyc (v14.0)	complete
	GO:0005694	chromosome	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006691	C	Seeded from EcoCyc (v14.0)	complete
	GO:0007062	sister chromatid cohesion	PMID:18765793^[10]	IMP: Inferred from Mutant Phenotype		P		complete
	GO:0005694	chromosome	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013757	C	Seeded from EcoCyc (v14.0)	complete
	GO:0005694	chromosome	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013758	C	Seeded from EcoCyc (v14.0)	complete
	GO:0005694	chromosome	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013760	C	Seeded from EcoCyc (v14.0)	complete
	GO:0006265	DNA topological change	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR002205	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006265	DNA topological change	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR005742	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006265	DNA topological change	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR006691	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006265	DNA topological change	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013757	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006265	DNA topological change	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013758	P	Seeded from EcoCyc (v14.0)	complete
	GO:0006265	DNA topological change	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013760	P	Seeded from EcoCyc (v14.0)	complete
	GO:0016853	isomerase activity	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0413	F	Seeded from EcoCyc (v14.0)	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	Notes	References	Evidence
Protein	Subunits of dimer of topoisomerase IV subunit A
Protein	yciH		PMID:16606699^[11]	Experiment(s):EBI-1144556
Protein	rplB		PMID:16606699^[11]	Experiment(s):EBI-1144556
Protein	rplA		PMID:16606699^[11]	Experiment(s):EBI-1144556
Protein	pflD		PMID:16606699^[11]	Experiment(s):EBI-1144556
Protein	aceF		PMID:15690043^[12]	Experiment(s):EBI-883350
Protein	lpdA		PMID:15690043^[12]	Experiment(s):EBI-883350
Protein	mreB		PMID:15690043^[12]	Experiment(s):EBI-883350
Protein	gyrA		PMID:15690043^[12]	Experiment(s):EBI-883350
Protein	secA		PMID:15690043^[12]	Experiment(s):EBI-883350
Protein	murF		PMID:15690043^[12]	Experiment(s):EBI-890645
Protein	rfaQ		PMID:15690043^[12]	Experiment(s):EBI-890645
Protein	rplL		PMID:15690043^[12]	Experiment(s):EBI-890645
Protein	rplM		PMID:15690043^[12]	Experiment(s):EBI-890645
Protein	rplV		PMID:15690043^[12]	Experiment(s):EBI-890645
Protein	rpmA		PMID:15690043^[12]	Experiment(s):EBI-890645
Protein	rpmG		PMID:15690043^[12]	Experiment(s):EBI-890645
Protein	rpsB		PMID:15690043^[12]	Experiment(s):EBI-890645
Protein	rpsJ		PMID:15690043^[12]	Experiment(s):EBI-890645
Protein	slyD		PMID:15690043^[12]	Experiment(s):EBI-890645
Protein	murF		PMID:19402753^[13]	LCMS(ID Probability):99.0
Protein	mreB		PMID:19402753^[13]	MALDI(Z-score):33.310369
Protein	rplB		PMID:19402753^[13]	MALDI(Z-score):37.621172
Protein	gyrA		PMID:19402753^[13]	MALDI(Z-score):26.844062
Protein	rfaQ		PMID:19402753^[13]	LCMS(ID Probability):99.0
Protein	rplL		PMID:19402753^[13]	LCMS(ID Probability):99.6
Protein	Subunits of topoisomerase IV	could be indirect
Protein	MreB		PMID:19187760^[14]	Purified MreB inhibits decatanation by Topo IV.
Protein	FtsK	FtsK stimulates Topo IV's decatenation activity in vitro	PMID:12939258^[15]	Two-hybrid analysis Immunoblotting
Protein	MukB		PMID:20696938^[16]
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source	Notes
cytoplasm			From EcoCyc^[3]
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	at EcoCyc MSDMAERLAL HEFTENAYLN YSMYVIMDRA LPFIGDGLKP VQRRIVYAMS ELGLNASAKF KKSARTVGDV LGKYHPHGDS ACYEAMVLMA QPFSYRYPLV DGQGNWGAPD DPKSFAAMRY TESRLSKYSE LLLSELGQGT ADWVPNFDGT LQEPKMLPAR LPNILLNGTT GIAVGMATDI PPHNLREVAQ AAIALIDQPK TTLDQLLDIV QGPDYPTEAE IITSRAEIRK IYENGRGSVR MRAVWKKEDG AVVISALPHQ VSGARVLEQI AAQMRNKKLP MVDDLRDESD HENPTRLVIV PRSNRVDMDQ VMNHLFATTD LEKSYRINLN MIGLDGRPAV KNLLEILSEW LVFRRDTVRR RLNYRLEKVL KRLHILEGLL VAFLNIDEVI EIIRNEDEPK PALMSRFGLT ETQAEAILEL KLRHLAKLEE MKIRGEQSEL EKERDQLQGI LASERKMNNL LKKELQADAQ AYGDDRRSPL QEREEAKAMS EHDMLPSEPV TIVLSQMGWV RSAKGHDIDA PGLNYKAGDS FKAAVKGKSN QPVVFVDSTG RSYAIDPITL PSARGQGEPL TGKLTLPPGA TVDHMLMESD DQKLLMASDA GYGFVCTFND LVARNRAGKA LITLPENAHV MPPVVIEDAS DMLLAITQAG RMLMFPVSDL PQLSKGKGNK IINIPSAEAA RGEDGLAQLY VLPPQSTLTI HVGKRKIKLR PEELQKVTGE RGRRGTLMRG LQRIDRVEID SPRRASSGDS EE
Length	752
Mol. Wt	83.833 kDa
pI	6.7 (calculated)
Extinction coefficient	55,810 - 56,060 (calc based on 19 Y, 5 W, and 2 C residues)
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<wikiPageContents>Image:1ZVU.pdb</wikiPageContents>

Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	References
Domain	591..638	PF03989 DNA gyrase C-terminal domain, beta-propeller	PMID:19920124^[17]
Domain	640..691	PF03989 DNA gyrase C-terminal domain, beta-propeller	PMID:19920124^[17]
Domain	29..466	PF00521 DNA gyrase/topoisomerase IV, subunit A	PMID:19920124^[17]
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=parC taxon=562,83333 </beststructure>

Models

View models at:

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See Help:Jmol in EcoliWiki

Text label
<jmol> <jmolApplet> <color>white</color> <uploadedFileContents >1ZVU.pdb</uploadedFileContents> <name></name> <script> wireframe off; spacefill off; trace off; rotate ON; cartoon; color chain; </script> </jmolApplet> </jmol>
<jmol> <jmolCheckbox > <scriptWhenChecked > rotate on; </scriptWhenChecked > <scriptWhenUnchecked > rotate off; </scriptWhenUnchecked > <checked>true</checked> <text>rotate</text> </jmolCheckbox > <jmolButton><script>reset; </script><text>reset</text></jmolButton> </jmol>

Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
Purification protocol	ParC(ΔCTD)	PMID:20081205^[18]
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
NCBI (Protein) (EcoliWiki Page)	GI:16130915	Escherichia coli str. K-12 substr. MG1655
NCBI (Protein) (EcoliWiki Page)	GeneID:947499	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0009916	Escherichia coli str. K-12 substr. MG1655
UniProt (EcoliWiki Page)	UniProtKB/Swiss-Prot:P0AFI2	Escherichia coli str. K-12 substr. MG1655
EcoCyc	EcoCyc:EG10686	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG10686	Escherichia coli str. K-12 substr. MG1655
NCBI (Gene) (EcoliWiki Page)	GeneID:947499	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120000679	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB0680	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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References

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See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ ^3.0 ^3.1 ^3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ Kato, J et al. (1988) Gene organization in the region containing a new gene involved in chromosome partition in Escherichia coli. J. Bacteriol. 170 3967-77 PubMed
↑ ^6.0 ^6.1 ^6.2 Kato, J et al. (1992) Purification and characterization of DNA topoisomerase IV in Escherichia coli. J. Biol. Chem. 267 25676-84 PubMed
↑ ^7.0 ^7.1 ^7.2 Peng, H & Marians, KJ (1993) Escherichia coli topoisomerase IV. Purification, characterization, subunit structure, and subunit interactions. J. Biol. Chem. 268 24481-90 PubMed
↑ ^8.0 ^8.1 ^8.2 Corbett, KD et al. (2005) The structural basis for substrate specificity in DNA topoisomerase IV. J. Mol. Biol. 351 545-61 PubMed
↑ Peng, H & Marians, KJ (1993) Decatenation activity of topoisomerase IV during oriC and pBR322 DNA replication in vitro. Proc. Natl. Acad. Sci. U.S.A. 90 8571-5 PubMed
↑ Wang, X et al. (2008) Modulation of Escherichia coli sister chromosome cohesion by topoisomerase IV. Genes Dev. 22 2426-33 PubMed
↑ ^11.0 ^11.1 ^11.2 ^11.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
↑ ^12.00 ^12.01 ^12.02 ^12.03 ^12.04 ^12.05 ^12.06 ^12.07 ^12.08 ^12.09 ^12.10 ^12.11 ^12.12 ^12.13 ^12.14 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
↑ ^13.0 ^13.1 ^13.2 ^13.3 ^13.4 ^13.5 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
↑ Madabhushi, R & Marians, KJ (2009) Actin homolog MreB affects chromosome segregation by regulating topoisomerase IV in Escherichia coli. Mol. Cell 33 171-80 PubMed
↑ Espeli, O et al. (2003) A physical and functional interaction between Escherichia coli FtsK and topoisomerase IV. J. Biol. Chem. 278 44639-44 PubMed
↑ Hayama, R & Marians, KJ (2010) Physical and functional interaction between the condensin MukB and the decatenase topoisomerase IV in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 107 18826-31 PubMed
↑ ^17.0 ^17.1 ^17.2 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
↑ Bigot, S & Marians, KJ (2010) DNA chirality-dependent stimulation of topoisomerase IV activity by the C-terminal AAA+ domain of FtsK. Nucleic Acids Res. 38 3031-40 PubMed

parC:Gene Product(s): Difference between revisions

Latest revision as of 20:58, 17 February 2015

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

@@ Line 35: / Line 35: @@
 *
 ****************************************************************************************** -->{{Product_nomenclature_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" {{Prettytable}}
+{| {{Prettytable}}  id="S46aacc9ec4c05"  class=" tableEdit Product_nomenclature_table"
 |-
@@ Line 44: / Line 44: @@
 !align=left {{table heading style}} |Synonyms
 ||
-DNA topoisomerase IV, subunit A<ref name='LIB:Riley_2006'/>, B3019<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ParC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
+''DNA topoisomerase IV, subunit A<ref name='LIB:Riley_2006'/>, B3019<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ParC<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK3010, JW2987, b3019''
+Category:Complex:topoisomerase IV
 |-
 !align=left {{table heading style}} |Product description
@@ Line 50: / Line 52: @@
 topoisomerase IV subunit A<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>;
-Component of [[:Category:Complex:dimer of topoisomerase IV subunit A|dimer of topoisomerase IV subunit A]]<ref name='LIB:EcoCyc11.1'/>; [[:Category:Complex:topoisomerase IV|topoisomerase IV]]<ref name='LIB:EcoCyc11.1'/>
+Component of [[Topoisomerase IV]]<ref name='LIB:EcoCyc11.1'/>
 Topoisomerase IV, subunit A, ATP-dependent, type II; chromosome decatenase; relaxes both positive and negative supercoils; DNA unknotting activity; heterotetrameric<ref name='LIB:EcoGene'/>
@@ Line 58: / Line 60: @@
 [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.- 5.99.1.-]<ref name='LIB:Riley_2006'/>
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.S46aacc9ec4c05&page=26428&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table] ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.S46aacc9ec4c05&page=26428&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.26428.S46aacc9ec4c05-->
@@ Line 65: / Line 67: @@
 <protect><!--Nomenclature_notes--></protect>
 ===Notes===
+More information about the Topo IV complex may be found on the [[Topoisomerase IV]] page.
 ==Function==
@@ Line 77: / Line 79: @@
 *
 ****************************************************************************************** -->{{Product_GO_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" {{Prettytable}}
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="P46aacca09a6d8"  class=" tableEdit GO_table_product dataTable"
 |- {{table_heading_style}}
-!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
+!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
+|-
+|
+|
+GO:0003918
+|
+DNA topoisomerase (ATP-hydrolyzing) activity
+|
+|
+IDA: Inferred from Direct Assay
+|
+|
+F
+|
+|
+Missing: reference
+|-
+|
+|
+GO:0007059
+|
+chromosome segregation
+|
+PMID:2842295
+|
+IMP: Inferred from Mutant Phenotype
+|
+|
+P
+|
+|
+complete
 |-
 |
@@ Line 88: / Line 128: @@
 DNA binding
 |
-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR002205<br />InterPro:IPR005742<br />InterPro:IPR006691<br />InterPro:IPR013757<br />InterPro:IPR013758<br />InterPro:IPR013760<br />SP_KW:KW-0238
+InterPro:IPR002205
 |
 F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
 |-
 |
+Contributes to
 |
 GO:0003916
@@ Line 107: / Line 147: @@
 DNA topoisomerase activity
 |
-GO_REF:0000002<br />GO_REF:0000004
+PMID:1334483
+|
+IDA: Inferred from Direct Assay
+|
+|
+F
+|
+|
+complete
+|-
+|
+|
+GO:0003677
+|
+DNA binding
+|
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR006691<br />SP_KW:KW-0799
+InterPro:IPR005742
 |
 F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
+|
+|
+GO:0019897
+|
+extrinsic to plasma membrane
+|
+PMID:1334483
+|
+IDA: Inferred from Direct Assay
+|
+|
+C
+|
+in the presence of DNA
 |
 complete
@@ Line 121: / Line 199: @@
 |
+|
+GO:0003677
+|
+DNA binding
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR006691
+|
+F
+|
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
+|
+|
+GO:0005737
+|
+cytoplasm
+|
+PMID:1334483
+|
+IDA: Inferred from Direct Assay
+|
+|
+C
+|
+in the presence of Mg2+
+|
+complete
+|-
+|
+|
+GO:0003677
+|
+DNA binding
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR013757
+|
+F
+|
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
+|
+Contributes to
 |
 GO:0003918
@@ Line 126: / Line 261: @@
 DNA topoisomerase (ATP-hydrolyzing) activity
 |
-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002
+PMID:8227000
 |
-IEA: Inferred from Electronic Annotation
+IDA: Inferred from Direct Assay
 |
-InterPro:IPR002205<br />InterPro:IPR005742<br />InterPro:IPR013757<br />InterPro:IPR013758<br />InterPro:IPR013760
 |
 F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
 |
 complete
@@ Line 141: / Line 276: @@
 |
-GO:0005524
+GO:0003677
 |
-ATP binding
+DNA binding
 |
-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR002205<br />InterPro:IPR005742<br />InterPro:IPR006691<br />InterPro:IPR013757<br />InterPro:IPR013758<br />InterPro:IPR013760
+InterPro:IPR013758
 |
 F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 160: / Line 295: @@
 |
-GO:0005694
+GO:0009330
 |
-chromosome
+DNA topoisomerase complex (ATP-hydrolyzing)
 |
-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002
+PMID:8227000
 |
-IEA: Inferred from Electronic Annotation
+IDA: Inferred from Direct Assay
 |
-InterPro:IPR002205<br />InterPro:IPR005742<br />InterPro:IPR006691<br />InterPro:IPR013757<br />InterPro:IPR013758<br />InterPro:IPR013760
 |
 C
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
 |
 complete
@@ Line 183: / Line 318: @@
 DNA topological change
 |
-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000002
+PMID:8227000
 |
-IEA: Inferred from Electronic Annotation
+IDA: Inferred from Direct Assay
 |
-InterPro:IPR002205<br />InterPro:IPR005742<br />InterPro:IPR006691<br />InterPro:IPR013757<br />InterPro:IPR013758<br />InterPro:IPR013760
 |
 P
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
 |
 complete
@@ Line 198: / Line 333: @@
 |
-GO:0006268
+GO:0003677
 |
-DNA unwinding during replication
+DNA binding
 |
-GO_REF:0000002<br />GO_REF:0000002
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR005742<br />InterPro:IPR006691
+InterPro:IPR013760
 |
-P
+F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 217: / Line 352: @@
 |
-GO:0007059
+GO:0003677
+|
+DNA binding
+|
+PMID:16023670
+|
+IDA: Inferred from Direct Assay
+|
 |
-chromosome segregation
+F
 |
-PMID:2842295
 |
-IMP: Inferred from Mutant Phenotype
+complete
+|-
 |
 |
-P
+GO:0003677
+|
+DNA binding
+|
+GOA:spkw<br />SP_KW:GO_REF:0000004
+|
+IEA: Inferred from Electronic Annotation
+|
+SP_KW:KW-0238
+|
+F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 236: / Line 390: @@
 |
-GO:0016853
+GO:0003916
 |
-isomerase activity
+DNA topoisomerase activity
 |
-GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-SP_KW:KW-0413
+InterPro:IPR006691
 |
 F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
 |-
 |
 |
-GO:0005737
+GO:0030541
 |
-cytoplasm
+plasmid partitioning
 |
-PMID:12535532
+PMID:8104339
 |
 IDA: Inferred from Direct Assay
 |
 |
-C
+P
 |
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
 |
 complete
@@ Line 274: / Line 428: @@
 |
-GO:0005886
+GO:0003916
 |
-plasma membrane
+DNA topoisomerase activity
 |
-GO_REF:0000004<br />GO_REF:0000023
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-SP_KW:KW-1003<br />SP_SL:SL-0039
+SP_KW:KW-0799
 |
-C
+F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 293: / Line 447: @@
 |
-GO:0016020
+GO:0003918
 |
-membrane
+DNA topoisomerase (ATP-hydrolyzing) activity
 |
-GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-SP_KW:KW-0472
+InterPro:IPR002205
 |
-C
+F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
 |-
 |
 |
-GO:0006261
+GO:0003918
 |
-DNA-dependent DNA replication
+DNA topoisomerase (ATP-hydrolyzing) activity
 |
-PMID:2170028
+GOA:interpro<br />GO_REF:0000002
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+InterPro:IPR005742
 |
-P
+F
 |
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
 |-
 |
 |
 GO:0003918
 |
 DNA topoisomerase (ATP-hydrolyzing) activity
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR013757
+|
+F
+|
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
 |
+|
+GO:0006265
+|
+DNA topological change
+|
+PMID:16023670
 |
 IDA: Inferred from Direct Assay
 |
+|
+P
+|
+|
+complete
+|-
+|
+|
+GO:0003918
+|
+DNA topoisomerase (ATP-hydrolyzing) activity
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR013758
 |
 F
 |
+Seeded from [[EcoCyc]] (v14.0)
 |
-required field missing
+complete
 |-
 |
@@ Line 354: / Line 546: @@
 chromosome segregation
 |
-PMID:2842295
+PMID:16023670
 |
-IMP: Inferred from Mutant Phenotype
+IDA: Inferred from Direct Assay
 |
@@ Line 367: / Line 559: @@
 |-
 |
-Contributes to
+|
+GO:0003918
+|
+DNA topoisomerase (ATP-hydrolyzing) activity
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR013760
+|
+F
+|
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
+|
+|
+GO:0005524
+|
+ATP binding
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR002205
+|
+F
+|
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
+|
+|
+GO:0005524
+|
+ATP binding
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR005742
+|
+F
+|
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
+|
+|
+GO:0005524
+|
+ATP binding
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
 |
-GO:0003916
+InterPro:IPR006691
 |
-DNA topoisomerase activity
+F
 |
-PMID:1334483
+Seeded from [[EcoCyc]] (v14.0)
 |
-IDA: Inferred from Direct Assay
+complete
+|-
 |
+|
+GO:0005524
+|
+ATP binding
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR013757
 |
 F
+|
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
 |
+|
+GO:0005524
+|
+ATP binding
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR013758
+|
+F
+|
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 388: / Line 675: @@
 |
-GO:0019897
+GO:0005524
+|
+ATP binding
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR013760
 |
-extrinsic to plasma membrane
+F
 |
-PMID:1334483
+Seeded from [[EcoCyc]] (v14.0)
 |
-IDA: Inferred from Direct Assay
+complete
+|-
 |
+|
+GO:0005694
+|
+chromosome
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR002205
 |
 C
 |
-in the presence of DNA
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 407: / Line 713: @@
 |
-GO:0005737
+GO:0005694
+|
+chromosome
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR005742
 |
-cytoplasm
+C
 |
-PMID:1334483
+Seeded from [[EcoCyc]] (v14.0)
 |
-IDA: Inferred from Direct Assay
+complete
+|-
 |
+|
+GO:0005694
+|
+chromosome
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR006691
 |
 C
 |
-in the presence of Mg2+
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
 |-
 |
-Contributes to
 |
-GO:0003918
+GO:0007062
 |
-DNA topoisomerase (ATP-hydrolyzing) activity
+sister chromatid cohesion
 |
-PMID:8227000
+PMID:18765793
 |
-IDA: Inferred from Direct Assay
+IMP: Inferred from Mutant Phenotype
 |
 |
-F
+P
 |
@@ Line 445: / Line 770: @@
 |
-GO:0009330
+GO:0005694
+|
+chromosome
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR013757
 |
-DNA topoisomerase complex (ATP-hydrolyzing)
+C
 |
-PMID:8227000
+Seeded from [[EcoCyc]] (v14.0)
 |
-IDA: Inferred from Direct Assay
+complete
+|-
 |
+|
+GO:0005694
+|
+chromosome
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR013758
 |
 C
+|
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
 |
+|
+GO:0005694
+|
+chromosome
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR013760
+|
+C
+|
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 468: / Line 831: @@
 DNA topological change
 |
-PMID:8227000
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR002205
+|
+P
+|
+Seeded from [[EcoCyc]] (v14.0)
 |
-IDA: Inferred from Direct Assay
+complete
+|-
 |
+|
+GO:0006265
+|
+DNA topological change
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR005742
 |
 P
+|
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
 |
+|
+GO:0006265
+|
+DNA topological change
+|
+GOA:interpro<br />GO_REF:0000002
+|
+IEA: Inferred from Electronic Annotation
+|
+InterPro:IPR006691
+|
+P
+|
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 483: / Line 884: @@
 |
-GO:0003677
+GO:0006265
 |
-DNA binding
+DNA topological change
 |
-PMID:16023670
+GOA:interpro<br />GO_REF:0000002
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+InterPro:IPR013757
 |
-F
+P
 |
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 502: / Line 903: @@
 |
-GO:0030541
+GO:0006265
 |
-plasmid partitioning
+DNA topological change
 |
-PMID:8104339
+GOA:interpro<br />GO_REF:0000002
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+InterPro:IPR013758
 |
 P
 |
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 522: / Line 922: @@
 |
-GO:0007062
+GO:0006265
 |
-sister chromatid cohesion
+DNA topological change
 |
-PMID:18765793
+GOA:interpro<br />GO_REF:0000002
 |
-IMP: Inferred from Mutant Phenotype
+IEA: Inferred from Electronic Annotation
 |
+InterPro:IPR013760
 |
 P
+|
+Seeded from [[EcoCyc]] (v14.0)
+|
+complete
+|-
 |
+|
+GO:0016853
+|
+isomerase activity
+|
+GOA:spkw<br />SP_KW:GO_REF:0000004
+|
+IEA: Inferred from Electronic Annotation
+|
+SP_KW:KW-0413
+|
+F
+|
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.P46aacca09a6d8&page=26428&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table] || || || || || || || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.P46aacca09a6d8&page=26428&pagename={{FULLPAGENAMEE}}&type=&template=GO_table_product edit table]</span> || || || || || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.26428.P46aacca09a6d8-->
@@ Line 551: / Line 970: @@
 *
 ****************************************************************************************** -->{{Product_interactions_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="A46aaccac8541e"  class=" tableEdit Product_interactions_table dataTable"
 |- {{table heading style}}
 !|Partner Type!!Partner!!Notes!!References!!Evidence
@@ Line 560: / Line 979: @@
 Subunits of [[:Category:Complex:dimer of topoisomerase IV subunit A|dimer of topoisomerase IV subunit A]]
 |
-could be indirect
 |
@@ Line 774: / Line 1,193: @@
 |
 Experiment(s):EBI-890645<br />
+|-
+|
+Protein
+|
+murF
+|
+|
+PMID:19402753
+|
+LCMS(ID Probability):99.0
+|-
+|
+Protein
+|
+mreB
+|
+|
+PMID:19402753
+|
+MALDI(Z-score):33.310369
+|-
+|
+Protein
+|
+rplB
+|
+|
+PMID:19402753
+|
+MALDI(Z-score):37.621172
+|-
+|
+Protein
+|
+gyrA
+|
+|
+PMID:19402753
+|
+MALDI(Z-score):26.844062
+|-
+|
+Protein
+|
+rfaQ
+|
+|
+PMID:19402753
+|
+LCMS(ID Probability):99.0
+|-
+|
+Protein
+|
+rplL
+|
+|
+PMID:19402753
+|
+LCMS(ID Probability):99.6
 |-
 |
@@ Line 794: / Line 1,279: @@
 |
 PMID:19187760
+|
+Purified MreB inhibits decatanation by Topo IV.
+|-
+|
+Protein
+|
+FtsK
+|
+FtsK stimulates Topo IV's decatenation activity ''in vitro''
+|
+PMID:12939258
+|
+*Two-hybrid analysis
+*Immunoblotting
+|-
+|
+Protein
+|
+MukB
+|
+|
+PMID:20696938
 |
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.A46aaccac8541e&page=26428&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.A46aaccac8541e&page=26428&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.26428.A46aaccac8541e-->
@@ Line 814: / Line 1,322: @@
 *
 ****************************************************************************************** -->{{Product_localization_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="Q46aaccae4a6a3"  class=" tableEdit Product_localization_table"
 |- {{table heading style}}
-!|Compartment!!Description!!Evidence!!Source!!Notes
+!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
 |-
 |
@@ Line 829: / Line 1,337: @@
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.Q46aaccae4a6a3&page=26428&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.Q46aaccae4a6a3&page=26428&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.26428.Q46aaccae4a6a3-->
@@ Line 849: / Line 1,357: @@
 *
 ****************************************************************************************** -->{{Product_physical_properties_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="Q46aaccafe0004"  class=" tableEdit Product_phys_prop_table"
+|-
+!align=left {{table heading style}} |Name
+||
 |-
@@ Line 885: / Line 1,397: @@
 ,810 - 56,060 (calc based on 19 Y, 5 W, and 2 C residues)
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.Q46aaccafe0004&page=26428&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.Q46aaccafe0004&page=26428&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.26428.Q46aaccafe0004-->
@@ Line 904: / Line 1,416: @@
 *
 ****************************************************************************************** -->{{Product_domains_motifs_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="Z46aaccb05c8e6"  class=" tableEdit Product_motif_table dataTable"
 |- {{table heading style}}
-!|Type!!Residues!!Description!!Notes
+!|Type!!Residues!!Description!!Notes!!References
+|-
+|
+Domain
+|
+..638
+|
+[http://pfam.janelia.org/family/PF03989 PF03989  DNA gyrase C-terminal domain, beta-propeller]
+|
-|-class='sortbottom'
+|
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+PMID:19920124
+|-
+|
+Domain
+|
+..691
+|
+[http://pfam.janelia.org/family/PF03989 PF03989  DNA gyrase C-terminal domain, beta-propeller]
+|
+|
+PMID:19920124
+|-
+|
+Domain
+|
+..466
+|
+[http://pfam.janelia.org/family/PF00521 PF00521  DNA gyrase/topoisomerase IV, subunit A]
+|
+|
+PMID:19920124
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.Z46aaccb05c8e6&page=26428&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.26428.Z46aaccb05c8e6--></td>
@@ Line 929: / Line 1,474: @@
 *
 ****************************************************************************************** -->{{Product_structure_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="Y46aaccb0bb9e0"  class=" tableEdit Product_structure_table"
 |-
@@ Line 942: / Line 1,487: @@
 ||
 View models at:
-* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
+* [http://www.proteinmodelportal.org/query/uniprot/P0AFI2 Protein Model Portal]
-* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
+* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0AFI2 PSI-PRED (P0AFI2)]
-* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
+* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0AFI2 Genomes TO Protein (P0AFI2)] (GTOP)
-* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
-* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.Y46aaccb0bb9e0&page=26428&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.Y46aaccb0bb9e0&page=26428&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.26428.Y46aaccb0bb9e0-->
@@ Line 989: / Line 1,532: @@
 *
 ****************************************************************************************** -->{{Product_resources_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="X46aaccb23fe78"  class=" tableEdit Product_resource_table"
 |- {{table_heading_style}}
 !|Resource type!!Source!!Notes/Reference
+|-
+|
+Purification protocol
+|
+ParC(&Delta;CTD)
+|
+PMID:20081205
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.X46aaccb23fe78&page=26428&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.26428.X46aaccb23fe78&page=26428&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.26428.X46aaccb23fe78-->
@@ Line 1,011: / Line 1,561: @@
 *
 ****************************************************************************************** -->{{Gene_accessions_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="T46aaccb29fad3"  class=" tableEdit Gene_accessions_table"
 |- {{table_heading_style}}
 !|Database!!Accession!!Notes
 |-
 |
-[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
+[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
 |
-[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10686-MONOMER EcoCyc:EG10686-MONOMER]
+[http://www.ncbi.nlm.nih.gov/protein/16130915 GI:16130915]
 |
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
+|
+[http://www.ncbi.nlm.nih.gov/protein/NP_417491.1 GeneID:947499]
+|
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[[ASAP]]
+|
+ASAP:ABE-0009916
+|
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
+|-
+|
+[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
+|
+[http://www.uniprot.org/uniprot/P0AFI2 UniProtKB/Swiss-Prot:P0AFI2]
+|
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[[EcoCyc]]
+|
+EcoCyc:EG10686
+|
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://swissmodel.expasy.org/repository/ SwissModel] ([[SwissModel|EcoliWiki Page]])
+[[EcoGene]]
 |
-[http://swissmodel.expasy.org/repository/smr.php?job=2&sptr_ac=P0AFI2 SwissModel:P0AFI2]
+EcoGene:EG10686
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
+[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
 |
-[[uniprot:P0AFI2|UniProt:P0AFI2]]
+[http://www.ncbi.nlm.nih.gov/gene?term=947499 GeneID:947499]
 |
+Escherichia coli str. K-12 substr. MG1655
 |-
 |
-[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
+[[RegulonDB]]
 |
-[http://pfam.sanger.ac.uk/family?acc=PF00521 PFAM:PF00521]
+RegulonDB:ECK120000679
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
+[[EchoBASE]]
 |
-[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_417491 RefSeq:NP_417491]
+EchoBASE:EB0680
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.26428.T46aaccb29fad3-->
@@ Line 1,068: / Line 1,646: @@
 *
 ****************************************************************************************** -->
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+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="C46aaccb7c2b24"  class=" tableEdit Links_table"
 |- {{table_heading_style}}
 !|Name!!URL!!Comments
-|-class='sortbottom'
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 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.26428.C46aaccb7c2b24-->
@@ Line 1,089: / Line 1,667: @@
 {{BacktoTop}}
 [[Category:Proteins]]
-[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0006261_!_DNA-dependent DNA replication]][[Category:Complex:dimer of topoisomerase IV subunit A]][[Category:Complex:topoisomerase IV]][[Category:Location:cytoplasm]][[Category:Products with structures in PDB]]

parC:Gene Product(s): Difference between revisions

Latest revision as of 20:58, 17 February 2015

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

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Notes

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