clpB:Gene Product(s): Difference between revisions

Standard name	ClpB
Synonyms	protein disaggregation chaperone^[1], B2592^[2]^[1], HtpM^[2]^[1], ClpB^[2]^[1], F84.1^[2]^[1], F68.5^[2]^[1], E89^[2]^[1] , ECK2590, htpM, JW2573, b2592
Product description	ClpB chaperone^[2]^[3] ATP-dependent protease and chaperone; protein disaggregation chaperone; role in de novo protein folding under mild stress conditions^[4]
EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier	GO ID	GO term name	Reference	Evidence Code	with/from	Aspect	Notes	Status
	GO:0000166	nucleotide binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003593	F	Seeded from EcoCyc (v14.0)	complete
	GO:0000166	nucleotide binding	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0547	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005515	protein binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004176	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR001270	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003959	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR013093	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR018368	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005524	ATP binding	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0067	F	Seeded from EcoCyc (v14.0)	complete
	GO:0005829	cytosol	PMID:16858726^[5]	IDA: Inferred from Direct Assay		C	Seeded from EcoCyc (v14.0)	complete
	GO:0006950	response to stress	GOA:spkw SP_KW:GO_REF:0000004	IEA: Inferred from Electronic Annotation	SP_KW:KW-0346	P	Seeded from EcoCyc (v14.0)	complete
	GO:0016020	membrane	PMID:16858726^[5]	IDA: Inferred from Direct Assay		C	Seeded from EcoCyc (v14.0)	complete
	GO:0017111	nucleoside-triphosphatase activity	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR003593	F	Seeded from EcoCyc (v14.0)	complete
	GO:0019538	protein metabolic process	GOA:interpro GO_REF:0000002	IEA: Inferred from Electronic Annotation	InterPro:IPR004176	P	Seeded from EcoCyc (v14.0)	complete
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type	Partner	References	Evidence
Protein	rpsB	PMID:15690043^[6]	Experiment(s):EBI-884811
Protein	tufA	PMID:15690043^[6]	Experiment(s):EBI-884811
Protein	ydeP	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	ccmB	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	rnz	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	glcB	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	lasT	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	ptsN	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	rplC	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	rplM	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	rplU	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	rplV	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	rpmC	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	rpsG	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	rpsH	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	rpsJ	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	rpsN	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	sapC	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	thiG	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	yagW	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	ygaU	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	yhfT	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	gfcB	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	evgS	PMID:15690043^[6]	Experiment(s):EBI-891673
Protein	putA	PMID:16606699^[7]	Experiment(s):EBI-1143404
Protein	uidC	PMID:16606699^[7]	Experiment(s):EBI-1143404
Protein	lacZ	PMID:16606699^[7]	Experiment(s):EBI-1143404
Protein	ptsP	PMID:16606699^[7]	Experiment(s):EBI-1143404
Protein	yjbH	PMID:16606699^[7]	Experiment(s):EBI-1143404
Protein	alaS	PMID:16606699^[7]	Experiment(s):EBI-1143404
Protein	ulaF	PMID:16606699^[7]	Experiment(s):EBI-1143404
Protein	phoB	PMID:16606699^[7]	Experiment(s):EBI-1143404
Protein	rplB	PMID:16606699^[7]	Experiment(s):EBI-1143404
Protein	sdhA	PMID:16606699^[7]	Experiment(s):EBI-1143404
Protein	nadE	PMID:16606699^[7]	Experiment(s):EBI-1143404
Protein	tufB	PMID:19402753^[8]	MALDI(Z-score):19.933263
Protein	tufB	PMID:19402753^[8]	MALDI(Z-score):19.933263
Small Molecule	AppppA (5',5'''-P1,P4-diadenosine tetraphosphate)	PMID:8468292^[9]	Photo-crosslinking with radioactively labelled azido-AppppA followed by 1-D and 2-D PAGE.
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment	Description	Evidence	Reference/Source	Notes
cytoplasm
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence	at EcoCyc MRLDRLTNKF QLALADAQSL ALGHDNQFIE PLHLMSALLN QEGGSVSPLL TSAGINAGQL RTDINQALNR LPQVEGTGGD VQPSQDLVRV LNLCDKLAQK RGDNFISSEL FVLAALESRG TLADILKAAG ATTANITQAI EQMRGGESVN DQGAEDQRQA LKKYTIDLTE RAEQGKLDPV IGRDEEIRRT IQVLQRRTKN NPVLIGEPGV GKTAIVEGLA QRIINGEVPE GLKGRRVLAL DMGALVAGAK YRGEFEERLK GVLNDLAKQE GNVILFIDEL HTMVGAGKAD GAMDAGNMLK PALARGELHC VGATTLDEYR QYIEKDAALE RRFQKVFVAE PSVEDTIAIL RGLKERYELH HHVQITDPAI VAAATLSHRY IADRQLPDKA IDLIDEAASS IRMQIDSKPE ELDRLDRRII QLKLEQQALM KESDEASKKR LDMLNEELSD KERQYSELEE EWKAEKASLS GTQTIKAELE QAKIAIEQAR RVGDLARMSE LQYGKIPELE KQLEAATQLE GKTMRLLRNK VTDAEIAEVL ARWTGIPVSR MMESEREKLL RMEQELHHRV IGQNEAVDAV SNAIRRSRAG LADPNRPIGS FLFLGPTGVG KTELCKALAN FMFDSDEAMV RIDMSEFMEK HSVSRLVGAP PGYVGYEEGG YLTEAVRRRP YSVILLDEVE KAHPDVFNIL LQVLDDGRLT DGQGRTVDFR NTVVIMTSNL GSDLIQERFG ELDYAHMKEL VLGVVSHNFR PEFINRIDEV VVFHPLGEQH IASIAQIQLK RLYKRLEERG YEIHISDEAL KLLSENGYDP VYGARPLKRA IQQQIENPLA QQILSGELVP GKVIRLEVNE DRIVAVQ
Length	857
Mol. Wt	95.587 kDa
pI	5.3 (calculated)
Extinction coefficient	36,330 - 36,705 (calc based on 17 Y, 2 W, and 3 C residues)
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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type	Residues	Description	References
Domain	202..341	PF00004 ATPase family associated with various cellular activities (AAA)	PMID:19920124^[10]
Domain	17..69	PF02861 Clp amino terminal domain	PMID:19920124^[10]
Domain	94..145	PF02861 Clp amino terminal domain	PMID:19920124^[10]
Domain	596..760	PF07724 AAA domain (Cdc48 subfamily)	PMID:19920124^[10]
Domain	766..854	PF10431 C-terminal, D2-small domain, of ClpB protein	PMID:19920124^[10]
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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=clpB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type	Source	Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database	Accession	Notes
NCBI (Protein) (EcoliWiki Page)	GI:16130513	Escherichia coli str. K-12 substr. MG1655
NCBI (Protein) (EcoliWiki Page)	GeneID:947077	Escherichia coli str. K-12 substr. MG1655
ASAP	ASAP:ABE-0008527	Escherichia coli str. K-12 substr. MG1655
UniProt (EcoliWiki Page)	UniProtKB/Swiss-Prot:P63284	Escherichia coli str. K-12 substr. MG1655
EcoCyc	EcoCyc:EG10157	Escherichia coli str. K-12 substr. MG1655
EcoGene	EcoGene:EG10157	Escherichia coli str. K-12 substr. MG1655
NCBI (Gene) (EcoliWiki Page)	GeneID:947077	Escherichia coli str. K-12 substr. MG1655
RegulonDB	RegulonDB:ECK120000153	Escherichia coli str. K-12 substr. MG1655
EchoBASE	EchoBASE:EB0155	Escherichia coli str. K-12 substr. MG1655
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Notes

Links

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Name	URL	Comments
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References

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See Help:References for how to manage references in EcoliWiki.

↑ ^1.0 ^1.1 ^1.2 ^1.3 ^1.4 ^1.5 ^1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
↑ ^2.0 ^2.1 ^2.2 ^2.3 ^2.4 ^2.5 ^2.6 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
↑ ^5.0 ^5.1 Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
↑ ^6.00 ^6.01 ^6.02 ^6.03 ^6.04 ^6.05 ^6.06 ^6.07 ^6.08 ^6.09 ^6.10 ^6.11 ^6.12 ^6.13 ^6.14 ^6.15 ^6.16 ^6.17 ^6.18 ^6.19 ^6.20 ^6.21 ^6.22 ^6.23 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
↑ ^7.00 ^7.01 ^7.02 ^7.03 ^7.04 ^7.05 ^7.06 ^7.07 ^7.08 ^7.09 ^7.10 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
↑ ^8.0 ^8.1 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
↑ Fuge, EK & Farr, SB (1993) AppppA-binding protein E89 is the Escherichia coli heat shock protein ClpB. J. Bacteriol. 175 2321-6 PubMed
↑ ^10.0 ^10.1 ^10.2 ^10.3 ^10.4 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

clpB:Gene Product(s): Difference between revisions

Latest revision as of 20:53, 17 February 2015

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

Links

References

Categories

Navigation menu

@@ Line 35: / Line 35: @@
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 ****************************************************************************************** -->{{Product_nomenclature_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
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@@ Line 44: / Line 44: @@
 !align=left {{table heading style}} |Synonyms
 ||
-protein disaggregation chaperone<ref name='LIB:Riley_2006'/>, B2592<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HtpM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ClpB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, F84.1<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, F68.5<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, E89<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>
+''protein disaggregation chaperone<ref name='LIB:Riley_2006'/>, B2592<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, HtpM<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, ClpB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, F84.1<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, F68.5<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, E89<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK2590, htpM, JW2573, b2592''
 |-
 !align=left {{table heading style}} |Product description
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+|- class="tableEdit_footer"
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+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.K46aab1daf09e4&page=25480&pagename={{FULLPAGENAMEE}}&type=1&template=Product_nomenclature_table edit table]</span> ||
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-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="Y46aab1dc175df"  class=" tableEdit GO_table_product dataTable"
 |- {{table_heading_style}}
-!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
+!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
 |-
 |
 |
-GO:0005524
+GO:0000166
 |
-ATP binding
+nucleotide binding
 |
-GO_REF:0000002<br />GO_REF:0000002<br />GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR001270<br />InterPro:IPR003959<br />SP_KW:KW-0067
+InterPro:IPR003593
 |
 F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 101: / Line 101: @@
 |
-GO:0005515
+GO:0000166
 |
-protein binding
+nucleotide binding
 |
-GO_REF:0000002
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR004176
+SP_KW:KW-0547
 |
 F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 120: / Line 120: @@
 |
-GO:0000166
+GO:0005515
 |
-nucleotide binding
+protein binding
 |
-GO_REF:0000002<br />GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR003593<br />SP_KW:KW-0547
+InterPro:IPR004176
 |
 F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 139: / Line 139: @@
 |
-GO:0005737
+GO:0005524
 |
-cytoplasm
+ATP binding
 |
-GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-SP_KW:KW-0963
+InterPro:IPR001270
 |
-C
+F
 |
-Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 158: / Line 158: @@
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-GO:0006950
+GO:0005524
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-response to stress
+ATP binding
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-GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-SP_KW:KW-0346
+InterPro:IPR003959
 |
-P
+F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 177: / Line 177: @@
 |
-GO:0017111
+GO:0005524
 |
-nucleoside-triphosphatase activity
+ATP binding
 |
-GO_REF:0000002
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR003593
+InterPro:IPR013093
 |
 F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 196: / Line 196: @@
 |
-GO:0019538
+GO:0005524
 |
-protein metabolic process
+ATP binding
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-GO_REF:0000002
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR004176
+InterPro:IPR018368
 |
-P
+F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 215: / Line 215: @@
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-GO:0005624
+GO:0005524
 |
-membrane fraction
+ATP binding
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-PMID:16858726
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+SP_KW:KW-0067
 |
-C
+F
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
 |-
 |
 |
-GO:0006457
+GO:0005829
 |
-protein folding
+cytosol
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+PMID:16858726
 |
+IDA: Inferred from Direct Assay
 |
 |
-P
+C
 |
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
+Seeded from [[EcoCyc]] (v14.0)
 |
-required fields missing
+complete
 |-
 |
 |
-GO:0005739
+GO:0006950
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-mitochondrion
+response to stress
 |
-PMID:16858726
+GOA:spkw<br />SP_KW:GO_REF:0000004
 |
-IDA: Inferred from Direct Assay
+IEA: Inferred from Electronic Annotation
 |
+SP_KW:KW-0346
 |
-C
+P
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 272: / Line 272: @@
 |
-GO:0005829
+GO:0016020
 |
-cytosol
+membrane
 |
 PMID:16858726
@@ Line 284: / Line 284: @@
 C
 |
-Seeded from EcoCyc <ref name = 'LIB:EcoCyc13.0'/>
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
@@ Line 291: / Line 291: @@
 |
-GO:0000166
+GO:0017111
 |
-nucleotide binding
+nucleoside-triphosphatase activity
 |
-GO_REF:0000002<br />GO_REF:0000004
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
 |
-InterPro:IPR003593<br />SP_KW:KW-0547
+InterPro:IPR003593
 |
 F
 |
-Seeded from EcoCyc
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
-|-
-|
-|
-GO:0009050
-|
-glycopeptide catabolic process
-|
-|
-|
-|
-P
-|
-Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.
-|
-required fields missing
 |-
 |
 |
-GO:0005515
+GO:0019538
 |
-protein binding
+protein metabolic process
 |
-GO_REF:0000002
+GOA:interpro<br />GO_REF:0000002
 |
 IEA: Inferred from Electronic Annotation
@@ Line 339: / Line 320: @@
 InterPro:IPR004176
 |
-F
+P
 |
-Seeded from EcoCyc
+Seeded from [[EcoCyc]] (v14.0)
 |
 complete
-|-class='sortbottom'
+|- class="tableEdit_footer"
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@@ Line 746: / Line 727: @@
 |
 Experiment(s):EBI-1143404<br />
+|-
+|
+Protein
+|
+tufB
+|
-|-class='sortbottom'
+|
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.H46aab1e881549&page=25480&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table] || || || ||
+PMID:19402753
+|
+MALDI(Z-score):19.933263
+|-
+|
+Protein
+|
+tufB
+|
+|
+PMID:19402753
+|
+MALDI(Z-score):19.933263
+|-
+|
+Small Molecule
+|
+AppppA (5',5<nowiki>'''</nowiki>-P1,P4-diadenosine tetraphosphate)
+|
+|
+PMID:8468292
+|
+Photo-crosslinking with radioactively labelled azido-AppppA followed by 1-D and 2-D PAGE.
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.H46aab1e881549&page=25480&pagename={{FULLPAGENAMEE}}&type=&template=Product_interactions_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25480.H46aab1e881549-->
@@ Line 764: / Line 778: @@
 *
 ****************************************************************************************** -->{{Product_localization_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="B46aab1e947882"  class=" tableEdit Product_localization_table"
 |- {{table heading style}}
-!|Compartment!!Description!!Evidence!!Notes
+!|Compartment!!Description!!Evidence!!Reference/Source!!Notes
 |-
 |
@@ Line 775: / Line 789: @@
 |
+|
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.B46aab1e947882&page=25480&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table] || || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.B46aab1e947882&page=25480&pagename={{FULLPAGENAMEE}}&type=&template=Product_localization_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25480.B46aab1e947882-->
@@ Line 798: / Line 814: @@
 *
 ****************************************************************************************** -->{{Product_physical_properties_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="S46aab1eada078"  class=" tableEdit Product_phys_prop_table"
+|-
+!align=left {{table heading style}} |Name
+||
 |-
@@ Line 826: / Line 846: @@
 !align=left {{table heading style}} |Mol. Wt
 ||
-.58 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
+.587 kDa
 |-
 !align=left {{table heading style}} |pI
 ||
+.3 (calculated)
 |-
 !align=left {{table heading style}} |Extinction coefficient
 ||
-- 36705 (calc based on 17 Y, 2 W, and 3 C residues)
+,330 - 36,705 (calc based on 17 Y, 2 W, and 3 C residues)
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.S46aab1eada078&page=25480&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table] ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.S46aab1eada078&page=25480&pagename={{FULLPAGENAMEE}}&type=1&template=Product_phys_prop_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25480.S46aab1eada078-->
@@ Line 851: / Line 871: @@
 *
 ****************************************************************************************** -->{{Product_domains_motifs_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="M46aab1eb54e7a"  class=" tableEdit Product_motif_table dataTable"
 |- {{table heading style}}
-!|Type!!Residues!!Description!!Notes
+!|Type!!Residues!!Description!!Notes!!References
+|-
+|
+Domain
+|
+..341
+|
+[http://pfam.janelia.org/family/PF00004 PF00004  ATPase family associated with various cellular activities (AAA)]
+|
-|-class='sortbottom'
+|
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.M46aab1eb54e7a&page=25480&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table] || || ||
+PMID:19920124
+|-
+|
+Domain
+|
+..69
+|
+[http://pfam.janelia.org/family/PF02861 PF02861  Clp amino terminal domain]
+|
+|
+PMID:19920124
+|-
+|
+Domain
+|
+..145
+|
+[http://pfam.janelia.org/family/PF02861 PF02861  Clp amino terminal domain]
+|
+|
+PMID:19920124
+|-
+|
+Domain
+|
+..760
+|
+[http://pfam.janelia.org/family/PF07724 PF07724  AAA domain (Cdc48 subfamily)]
+|
+|
+PMID:19920124
+|-
+|
+Domain
+|
+..854
+|
+[http://pfam.janelia.org/family/PF10431 PF10431  C-terminal, D2-small domain, of ClpB protein ]
+|
+|
+PMID:19920124
+|- class="tableEdit_footer"
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.M46aab1eb54e7a&page=25480&pagename={{FULLPAGENAMEE}}&type=&template=Product_motif_table edit table]</span> || || || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25480.M46aab1eb54e7a--></td>
@@ Line 867: / Line 942: @@
 </table>
-<span id="Structure"></span><big>'''Structure'''</big>
+<table><tr valign='top'><td>
+<span id='Structure'></span><big>'''Structure'''</big><br />
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25480.S46aab1ebb2bf3-->
 <!--
@@ Line 875: / Line 951: @@
 *
 ****************************************************************************************** -->{{Product_structure_help}}
-{|border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{|   id="S46aab1ebb2bf3"  class=" tableEdit Product_structure_table"
 |-
 !align=left {{table heading style}} |Structures
 ||
-<beststructure>clpB
+<beststructure>
-</beststructure>
+gene=clpB
+taxon=562,83333
+</beststructure>
 |-
 !align=left {{table heading style}} |Models
 ||
 View models at:
-* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=clpB&sub=keywordSearc EcoliPredict]
+* [http://www.proteinmodelportal.org/query/uniprot/P63284 Protein Model Portal]
-* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=clpB&organism=562&organismtext= ModBase]
+* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P63284 PSI-PRED (P63284)]
-* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
+* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P63284 Genomes TO Protein (P63284)] (GTOP)
-* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
-* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.S46aab1ebb2bf3&page=25480&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table] ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.S46aab1ebb2bf3&page=25480&pagename={{FULLPAGENAMEE}}&type=1&template=Product_structure_table edit table]</span> ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25480.S46aab1ebb2bf3-->
-<!--Structure_notes--></protect>
+</td><td></protect>
+==== Structure figures ====
+<protect><!--          ***** PLEASE DO NOT EDIT BELOW THIS LINE *****         -->
+</td><tr><table><!--Structure_notes--></protect>
 ===Notes===
@@ Line 912: / Line 1,007: @@
 *
 ****************************************************************************************** -->{{Product_resources_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="G46aab1ed31a17"  class=" tableEdit Product_resource_table"
 |- {{table_heading_style}}
 !|Resource type!!Source!!Notes/Reference
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.G46aab1ed31a17&page=25480&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.G46aab1ed31a17&page=25480&pagename={{FULLPAGENAMEE}}&type=&template=Product_resource_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25480.G46aab1ed31a17-->
@@ Line 934: / Line 1,029: @@
 *
 ****************************************************************************************** -->{{Gene_accessions_help}}
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="I46aab1ed9023f"  class=" tableEdit Gene_accessions_table"
 |- {{table_heading_style}}
 !|Database!!Accession!!Notes
 |-
 |
-[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
+[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
+|
+[http://www.ncbi.nlm.nih.gov/protein/16130513 GI:16130513]
+|
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
+|
+[http://www.ncbi.nlm.nih.gov/protein/NP_417083.1 GeneID:947077]
+|
+Escherichia coli str. K-12 substr. MG1655
+|-
+|
+[[ASAP]]
+|
+ASAP:ABE-0008527
+|
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
+|-
+|
+[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
 |
-[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG10157-MONOMER EcoCyc:EG10157-MONOMER]
+[http://www.uniprot.org/uniprot/P63284 UniProtKB/Swiss-Prot:P63284]
 |
+Escherichia coli str. K-12 substr. MG1655
 |-
 |
-[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
+[[EcoCyc]]
 |
-[[uniprot:P63284|UniProt:P63284]]
+EcoCyc:EG10157
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
+[[EcoGene]]
 |
-[http://pfam.sanger.ac.uk/family?acc=PF02861 PFAM:PF02861]
+EcoGene:EG10157
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
+[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
 |
-[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_417083 RefSeq:NP_417083]
+[http://www.ncbi.nlm.nih.gov/gene?term=947077 GeneID:947077]
 |
+Escherichia coli str. K-12 substr. MG1655
 |-
 |
-[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
+[[RegulonDB]]
 |
-[http://salilab.org/modbase/searchbyid?databaseID=P63284 ModBase:P63284]
+RegulonDB:ECK120000153
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
 |-
 |
-[http://www.rcsb.org/pdb PDB] ([[PDB|EcoliWiki Page]])
+[[EchoBASE]]
 |
-[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1JBK PDB:1JBK]
+EchoBASE:EB0155
 |
+''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.I46aab1ed9023f&page=25480&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.I46aab1ed9023f&page=25480&pagename={{FULLPAGENAMEE}}&type=0&template=Gene_accessions_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25480.I46aab1ed9023f-->
@@ Line 998: / Line 1,114: @@
 *
 ****************************************************************************************** -->
-{|class = 'sortable' border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"
+{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="W46a849eca0546"  class=" tableEdit Links_table"
 |- {{table_heading_style}}
 !|Name!!URL!!Comments
-|-class='sortbottom'
+|- class="tableEdit_footer"
-|[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.W46a849eca0546&page=25480&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table] || ||
+|<span class="tableEdit_editLink plainlinks">[{{SERVER}}{{SCRIPTPATH}}?title=Special:TableEdit&id=421aa90e079fa326b6494f812ad13e79.25480.W46a849eca0546&page=25480&pagename={{FULLPAGENAMEE}}&type=0&template=Links_table edit table]</span> || ||
 |}
 <!--box uid=421aa90e079fa326b6494f812ad13e79.25480.W46a849eca0546-->
@@ Line 1,013: / Line 1,129: @@
 ==References==
 {{BacktoTop}}
+{{RefHelp}}
-<references/>
+<references />
 __NOTOC__
-</noinclude>
 ===Categories===
 {{BacktoTop}}
 [[Category:Proteins]]
-[[Category:GO:0006457_!_protein folding]][[Category:GO:0009050_!_glycopeptide catabolic process]][[Category:GO:0005737_!_cytoplasm]][[Category:Location:cytoplasm]][[Category:Products with structures in PDB]]

clpB:Gene Product(s): Difference between revisions

Latest revision as of 20:53, 17 February 2015

Nomenclature

Notes

Function

Notes

Localization

Notes

Structure and Physical Properties

Structure figures

Notes

Gene Product Resources

Notes

Accessions in Other Databases

Notes

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