gltA:Gene Product(s): Difference between revisions

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{|  id="M46aa3f2da2ad9"  class=" tableEdit Product_nomenclature_table" 
 
|-
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!{{table heading style}} |Standard name
!align=left {{table heading style}} |Standard name
|
||
GltA product
GltA  
|-
|-
!{{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
|
||
citrate synthase product<ref name='LIB:Riley_2006'/>, B0720 product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, IcdB product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GltA product<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''citrate synthase<ref name='LIB:Riley_2006'/>, B0720<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, IcdB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GltA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0709, gluT, icdB, JW0710, b0720''
|-
|-
!{{table heading style}} |Product description
!align=left {{table heading style}} |Product description
|
||
citrate synthase monomer<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>
citrate synthase<ref name='LIB:EcoCyc10.6'/><ref name='LIB:EcoCyc11.1'/>


Citrate synthase; hexameric<ref name='LIB:EcoGene'/>
|-
|-
!{{table heading style}} |EC number (for enzymes)
!align=left {{table heading style}} |EC number (for enzymes)
|
||
** [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.1 2.3.3.1]<ref name='LIB:Riley_2006'/>
* [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.1 2.3.3.1]<ref name='LIB:Riley_2006'/>
|-
 
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<protect><!--Nomenclature_notes--></protect>
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===Notes===
===Notes===
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{{BacktoTop}}
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<protect>
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<big>'''Gene Ontology'''</big><br />{{Product_GO_help}}<!--box uid=421aa90e079fa326b6494f812ad13e79.21195.R46aa3f2e9e242-->
<big>'''Gene Ontology'''</big><br /><!--box uid=421aa90e079fa326b6494f812ad13e79.21195.R46aa3f2e9e242-->
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;" id="R46aa3f2e9e242"  class=" tableEdit GO_table_product dataTable" 
|- {{table_heading_style}}
|- {{table_heading_style}}
!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
|-  
|-  
|
|


|
|
[[Category:GO:0003824_!_catalytic_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003824_!_catalytic_activity GO:0003824]
GO:0004108
|
|
catalytic activity
citrate (Si)-synthase activity
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|
GO_REF:0000004
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
SP_KW:KW-0021
InterPro:IPR010953
|
|
F
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
[[Category:GO:0004108_!_citrate_(Si)-synthase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0004108_!_citrate_(Si)-synthase_activity GO:0004108]
GO:0004108
|
|
citrate (Si)-synthase activity
citrate (Si)-synthase activity
|
|
GO_REF:0000002
GOA:spec<br />GO_REF:0000003
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR010953
EC:2.3.3.1
|
|
F
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
Line 117: Line 120:


|
|
[[Category:GO:0004108_!_citrate_(Si)-synthase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0004108_!_citrate_(Si)-synthase_activity GO:0004108]
GO:0003878
|
|
citrate (Si)-synthase activity
ATP citrate synthase activity
|
|
GO_REF:0000003
 
|
|
IEA: Inferred from Electronic Annotation
 
|
|
EC:2.3.3.1
 
|
|
F
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
 
|
|
complete
Missing: evidence, reference
|-  
|-  
|
|


|
|
[[Category:GO:0005624_!_membrane_fraction]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0005624_!_membrane_fraction GO:0005624]
GO:0005829
|
|
membrane fraction
cytosol
|
|
[[PMID:16858726]]<ref name=PMID:16858726/>
PMID:16858726
|
|
IDA: Inferred from Direct Assay
IDA: Inferred from Direct Assay
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C
C
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
Line 155: Line 158:


|
|
[[Category:GO:0005737_!_cytoplasm]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0005737_!_cytoplasm GO:0005737]
GO:0006099
|
|
cytoplasm
tricarboxylic acid cycle
|
|
GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR010953
InterPro:IPR019810
|
|
C
P
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
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|
|
[[Category:GO:0006099_!_tricarboxylic_acid_cycle]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006099_!_tricarboxylic_acid_cycle GO:0006099]
GO:0006099
|
|
tricarboxylic acid cycle
tricarboxylic acid cycle
|
|
GO_REF:0000004
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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P
P
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
Line 193: Line 196:


|
|
[[Category:GO:0016740_!_transferase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0016740_!_transferase_activity GO:0016740]
GO:0006099
|
tricarboxylic acid cycle
|
PMID:13367004
|
IMP: Inferred from Mutant Phenotype
|
 
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0016020
|
membrane
|
PMID:16858726
|
IDA: Inferred from Direct Assay
|
 
|
C
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
GO:0016740
|
|
transferase activity
transferase activity
|
|
GO_REF:0000004
GOA:spkw<br />SP_KW:GO_REF:0000004
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
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F
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
|-  
|-  
|
|
 
|
GO:0044262
|
cellular carbohydrate metabolic process
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002020
|
P
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
 
|
|
[[Category:GO:0006099_!_tricarboxylic_acid_cycle]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0006099_!_tricarboxylic_acid_cycle GO:0006099]
GO:0044262
|
|
tricarboxylic acid cycle
cellular carbohydrate metabolic process
|
|
[[PMID:13152052]]<ref name=PMID:13152052/>
GOA:interpro<br />GO_REF:0000002
|
|
IDA: Inferred from Direct Assay
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR010953
|
|
P
P
|
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.  
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  
|-  
|-  
|
|
 
|
|
[[Category:GO:0009061_!_anaerobic_respiration]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0009061_!_anaerobic_respiration GO:0009061]
GO:0044262
|
|
anaerobic respiration
cellular carbohydrate metabolic process
|
|
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR016141
|
|
P  
P
|
|
Seeded from EcoCyc 11.1<ref name='LIB:EcoCyc11.1'/>.  
Seeded from [[EcoCyc]] (v14.0)
|
|
required fields missing 
complete
|-  
|-  
|
|
 
|
GO:0044262
|
cellular carbohydrate metabolic process
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR016142
|
P
|
|
[[Category:GO:0003878_!_ATP_citrate_synthase_activity]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0003878_!_ATP_citrate_synthase_activity GO:0003878]
Seeded from [[EcoCyc]] (v14.0)
|
|
ATP citrate synthase activity
complete
|-
|
|


|
|
GO:0046912
|
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR002020
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
|


|
GO:0046912
|
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR016141
|
|
F
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-
|
|


|
|
required field missing
GO:0046912
|
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
|
GOA:interpro<br />GO_REF:0000002
|
IEA: Inferred from Electronic Annotation
|
InterPro:IPR016142
|
F
|
Seeded from [[EcoCyc]] (v14.0)
|
complete
|-  
|-  
|
|


|
|
[[Category:GO:0046912_!_transferase_activity,_transferring_acyl_groups,_acyl_groups_converted_into_alkyl_on_transfer]][http://gowiki.tamu.edu/wiki/index.php/Category:GO:0046912_!_transferase_activity,_transferring_acyl_groups,_acyl_groups_converted_into_alkyl_on_transfer GO:0046912]
GO:0046912
|
|
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
|
|
GO_REF:0000002
GOA:interpro<br />GO_REF:0000002
|
|
IEA: Inferred from Electronic Annotation
IEA: Inferred from Electronic Annotation
|
|
InterPro:IPR002020
InterPro:IPR019810
|
|
F
F
|
|
Seeded from EcoCyc 12.5 <ref name = 'LIB:EcoCyc12.5'/>
Seeded from [[EcoCyc]] (v14.0)
|
|
complete  
complete  


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!Partner Type!!Partner!!Notes
!|Partner Type!!Partner!!Notes!!References!!Evidence
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Protein
|
matC<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137791<br />
|-
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Protein
|
groL<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137791<br />
|-
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Protein
|
nadE<br />
|
 
|
PMID:16606699
|
Experiment(s):EBI-1137791<br />
|-
|
Protein
|
rraB
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
rho
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
iscS
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.2
|-
|
Protein
|
ybgI
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
dnaN
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
rfaD
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
osmY
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.4
|-
|
Protein
|
acnA
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
groS
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
tig
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
glnE
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.6
|-
|
Protein
|
astC
|
 
|
PMID:19402753
|
LCMS(ID Probability):99.4
 
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<!--Function_notes--></protect>
<!--Function_notes--></protect>
===Notes===
===Notes===
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{|{{Prettytable}}
{|   id="P46aa3f3ed25db"  class=" tableEdit Product_phys_prop_table" 
 
|-
!align=left {{table heading style}} |Name
||
 
|-
|-
!{{table heading style}} |Sequence
!align=left {{table heading style}} |Sequence
|
||
[http://biocyc.org/ECOLI/sequence-aa?object=CITSYN-MONOMER at EcoCyc]  
[http://biocyc.org/ECOLI/sequence-aa?object=CITSYN-MONOMER at EcoCyc]  
<pre>MADTKAKLTL NGDTAVELDV LKGTLGQDVI DIRTLGSKGV FTFDPGFTST ASCESKITFI
<pre>MADTKAKLTL NGDTAVELDV LKGTLGQDVI DIRTLGSKGV FTFDPGFTST ASCESKITFI
Line 356: Line 645:
FKSDIKR</pre>  
FKSDIKR</pre>  
|-
|-
!{{table heading style}} |Mol. Wt
!align=left {{table heading style}} |Length
|
||
48.01 kDa (calc) <ref name='LIB:EcoCyc10.6'/>
427
|-
|-
!{{table heading style}} |pI
!align=left {{table heading style}} |Mol. Wt
|
||
6.62<ref name='LIB:EcoCyc10.6'/>
48.016 kDa
|-
|-
!{{table heading style}} |Extinction coefficient
!align=left {{table heading style}} |pI
|
||
40340 - 41215 (calc based on 16 Y, 3 W, and 7 C residues)  
6.7 (calculated)
|-
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!align=left {{table heading style}} |Extinction coefficient
||
40,340 - 41,215 (calc based on 16 Y, 3 W, and 7 C residues)
 
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<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span>
 
<!--box uid=421aa90e079fa326b6494f812ad13e79.21195.O46aa3f3f394a3-->
<span id="Domains/Motifs/Modification Sites"><big>'''Domains/Motifs/Modification Sites'''</big></span><table>
<tr align="left" valign="top">
<td><!--box uid=421aa90e079fa326b6494f812ad13e79.21195.O46aa3f3f394a3-->
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|- {{table heading style}}
|- {{table heading style}}
!Type!!Residues!!Description!!Notes
!|Type!!Residues!!Description!!Notes!!References
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|
Domain
|
46..409
|
[http://pfam.janelia.org/family/PF00285 PF00285  Citrate synthase]
|
 
|
PMID:19920124
 
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{{Product_domains_motifs_help}}
<td>
<!-- motifs column 2-->
<motif_map/>
</td>
</tr>
</table>


<span id="Structure"></span><big>'''Structure'''</big>
<table><tr valign='top'><td>
<span id='Structure'></span><big>'''Structure'''</big><br />
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|-
|-
!align=left {{table heading style}} |Structures
!align=left {{table heading style}} |Structures
||
||
<beststructure>gltA
<beststructure>
562</beststructure>
gene=gltA
 
taxon=562,83333
</beststructure>
|-
|-
!align=left {{table heading style}} |Models
!align=left {{table heading style}} |Models
||
||
View models at:
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=gltA&sub=keywordSearc EcoliPredict]
* [http://www.proteinmodelportal.org/query/uniprot/P0ABH7 Protein Model Portal]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=gltA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0ABH7 PSI-PRED (P0ABH7)]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0ABH7 Genomes TO Protein (P0ABH7)] (GTOP)
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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<!--Structure_notes--></protect>
</td><td></protect>
==== Structure figures ====
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
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===Notes===
===Notes===


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===Notes===
===Notes===
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|- {{table_heading_style}}
|- {{table_heading_style}}
!Database!!Accession!!Notes
!|Database!!Accession!!Notes
|-
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/16128695 GI:16128695]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
|
[http://www.ncbi.nlm.nih.gov/protein/NP_415248.1 GeneID:945323]
|
Escherichia coli str. K-12 substr. MG1655
|-
|
[[ASAP]]
|
ASAP:ABE-0002451
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
|
|
[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
|
|
[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=CITSYN-MONOMER EcoCyc:CITSYN-MONOMER]
[http://www.uniprot.org/uniprot/P0ABH7 UniProtKB/Swiss-Prot:P0ABH7]
|
|
Escherichia coli str. K-12 substr. MG1655
|-
|-  
|
|
[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
[[EcoCyc]]
|
|
[[uniprot:P0ABH7|UniProt:P0ABH7]] 
EcoCyc:EG10402
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|-  
|
|
[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
[[EcoGene]]
|
|
[http://pfam.sanger.ac.uk/family?acc=PF00285 PFAM:PF00285] 
EcoGene:EG10402
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|-  
|
|
[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
|
[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415248 RefSeq:NP_415248]
[http://www.ncbi.nlm.nih.gov/gene?term=945323 GeneID:945323]
|
|
Escherichia coli str. K-12 substr. MG1655
|-
|-  
|
|
[http://modbase.compbio.ucsf.edu ModBase] ([[ModBase|EcoliWiki Page]])
[[RegulonDB]]
|
|
[http://salilab.org/modbase/searchbyid?databaseID=P0ABH7 ModBase:P0ABH7] 
RegulonDB:ECK120000395
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-
|-  
|
|
[http://www.rcsb.org/pdb PDB] ([[PDB|EcoliWiki Page]])
[[EchoBASE]]
|
|
[http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=1K3P PDB:1K3P] 
EchoBASE:EB0397
|
|
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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===Notes===
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{{BacktoTop}}
{{RefHelp}}
{{RefHelp}}
<references/>
<references />
__NOTOC__
__NOTOC__
</noinclude>
===Categories===
===Categories===
{{BacktoTop}}
{{BacktoTop}}
[[Category:Proteins]]
[[Category:Proteins]]
[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0006099_!_tricarboxylic acid cycle]][[Category:GO:0009061_!_anaerobic respiration]][[Category:Products with structures in PDB]]

Latest revision as of 20:29, 17 February 2015

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

GltA

Synonyms

citrate synthase[1], B0720[2][1], IcdB[2][1], GltA[2][1] , ECK0709, gluT, icdB, JW0710, b0720

Product description

citrate synthase[2][3]

Citrate synthase; hexameric[4]

EC number (for enzymes)
edit table


Notes

Function

[back to top]


Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004108

citrate (Si)-synthase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010953

F

Seeded from EcoCyc (v14.0)

complete

GO:0004108

citrate (Si)-synthase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.3.3.1

F

Seeded from EcoCyc (v14.0)

complete

GO:0003878

ATP citrate synthase activity

F

Missing: evidence, reference

GO:0005829

cytosol

PMID:16858726[5]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc (v14.0)

complete

GO:0006099

tricarboxylic acid cycle

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019810

P

Seeded from EcoCyc (v14.0)

complete

GO:0006099

tricarboxylic acid cycle

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0816

P

Seeded from EcoCyc (v14.0)

complete

GO:0006099

tricarboxylic acid cycle

PMID:13367004[6]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

PMID:16858726[5]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc (v14.0)

complete

GO:0016740

transferase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc (v14.0)

complete

GO:0044262

cellular carbohydrate metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002020

P

Seeded from EcoCyc (v14.0)

complete

GO:0044262

cellular carbohydrate metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010953

P

Seeded from EcoCyc (v14.0)

complete

GO:0044262

cellular carbohydrate metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016141

P

Seeded from EcoCyc (v14.0)

complete

GO:0044262

cellular carbohydrate metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016142

P

Seeded from EcoCyc (v14.0)

complete

GO:0046912

transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002020

F

Seeded from EcoCyc (v14.0)

complete

GO:0046912

transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016141

F

Seeded from EcoCyc (v14.0)

complete

GO:0046912

transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016142

F

Seeded from EcoCyc (v14.0)

complete

GO:0046912

transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019810

F

Seeded from EcoCyc (v14.0)

complete

edit table

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

matC

PMID:16606699[7]

Experiment(s):EBI-1137791

Protein

groL

PMID:16606699[7]

Experiment(s):EBI-1137791

Protein

nadE

PMID:16606699[7]

Experiment(s):EBI-1137791

Protein

rraB

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

rho

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

iscS

PMID:19402753[8]

LCMS(ID Probability):99.2

Protein

ybgI

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

dnaN

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

rfaD

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

osmY

PMID:19402753[8]

LCMS(ID Probability):99.4

Protein

acnA

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

groS

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

tig

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

glnE

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

astC

PMID:19402753[8]

LCMS(ID Probability):99.4

edit table


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
edit table


Notes

Structure and Physical Properties

[back to top]


Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MADTKAKLTL NGDTAVELDV LKGTLGQDVI DIRTLGSKGV FTFDPGFTST ASCESKITFI
DGDEGILLHR GFPIDQLATD SNYLEVCYIL LNGEKPTQEQ YDEFKTTVTR HTMIHEQITR
LFHAFRRDSH PMAVMCGITG ALAAFYHDSL DVNNPRHREI AAFRLLSKMP TMAAMCYKYS
IGQPFVYPRN DLSYAGNFLN MMFSTPCEPY EVNPILERAM DRILILHADH EQNASTSTVR
TAGSSGANPF ACIAAGIASL WGPAHGGANE AALKMLEEIS SVKHIPEFVR RAKDKNDSFR
LMGFGHRVYK NYDPRATVMR ETCHEVLKEL GTKDDLLEVA MELENIALND PYFIEKKLYP
NVDFYSGIIL KAMGIPSSMF TVIFAMARTV GWIAHWSEMH SDGMKIARPR QLYTGYEKRD
FKSDIKR
Length

427

Mol. Wt

48.016 kDa

pI

6.7 (calculated)

Extinction coefficient

40,340 - 41,215 (calc based on 16 Y, 3 W, and 7 C residues)

edit table


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

46..409

PF00285 Citrate synthase

PMID:19920124[9]

edit table

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=gltA taxon=562,83333 </beststructure>

Models

View models at:

edit table

Structure figures

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table


Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128695

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945323

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0002451

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0ABH7

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10402

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10402

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945323

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000395

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0397

Escherichia coli str. K-12 substr. MG1655

edit table


Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
  6. ↑ DAVIS, BD & GILVARG, C (1956) The role of the tricarboxylic acid cycle in acetate oxidation in Escherichia coli. J. Biol. Chem. 222 307-19 PubMed
  7. ↑ 7.0 7.1 7.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  8. ↑ 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 8.11 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  9. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

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