gltA:Gene Product(s): Difference between revisions

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!align=left {{table heading style}} |Synonyms
!align=left {{table heading style}} |Synonyms
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citrate synthase<ref name='LIB:Riley_2006'/>, B0720<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, IcdB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GltA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>  
''citrate synthase<ref name='LIB:Riley_2006'/>, B0720<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, IcdB<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/>, GltA<ref name='LIB:EcoCyc10.6'/><ref name='LIB:Riley_2006'/> , ECK0709, gluT, icdB, JW0710, b0720''
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!align=left {{table heading style}} |Product description
!align=left {{table heading style}} |Product description
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|- {{table_heading_style}}
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!|Qualifier!!GO ID!!GO term name!!Reference(s)!!Evidence Code!!with/from!!Aspect!!Notes!!Status
!|Qualifier!!GO ID!!GO term name!!Reference!!Evidence Code!!with/from!!Aspect!!Notes!!Status
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{| border="2" cellpadding="4" cellspacing="0" style="margin: 1em 1em 1em 0; border: 1px #aaa solid; border-collapse: collapse;"  id="U46aa3f3d1d880"  class=" tableEdit Product_interactions_table dataTable"   
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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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Experiment(s):EBI-1137791<br />  
Experiment(s):EBI-1137791<br />  
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Protein
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rraB
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PMID:19402753
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LCMS(ID Probability):99.6
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Protein
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rho
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PMID:19402753
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LCMS(ID Probability):99.6
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Protein
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iscS
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PMID:19402753
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LCMS(ID Probability):99.2
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Protein
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ybgI
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PMID:19402753
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LCMS(ID Probability):99.6
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Protein
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dnaN
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PMID:19402753
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LCMS(ID Probability):99.6
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Protein
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rfaD
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PMID:19402753
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LCMS(ID Probability):99.6
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Protein
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osmY
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PMID:19402753
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LCMS(ID Probability):99.4
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Protein
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acnA
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PMID:19402753
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LCMS(ID Probability):99.6
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Protein
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groS
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PMID:19402753
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LCMS(ID Probability):99.6
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Protein
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tig
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PMID:19402753
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LCMS(ID Probability):99.6
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Protein
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glnE
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PMID:19402753
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LCMS(ID Probability):99.6
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Protein
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astC
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PMID:19402753
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LCMS(ID Probability):99.4


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!|Type!!Residues!!Description!!Notes!!References
!|Type!!Residues!!Description!!Notes!!References
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View models at:
View models at:
* [http://dragon.bio.purdue.edu/ecolpredict2/localsearch/cgi-bin/search3.cgi?q=recA EcoliPredict]
* [http://www.proteinmodelportal.org/query/uniprot/P0ABH7 Protein Model Portal]
* [http://modbase.compbio.ucsf.edu/modbase-cgi/model_search.cgi?searchmode=default&displaymode=moddetail&searchproperties=ALL&searchvalue=recA&organism=562&organismtext= ModBase]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0ABH7 PSI-PRED (P0ABH7)]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0ABH7 Genomes TO Protein (P0ABH7)] (GTOP)
* [http://www.ebi.ac.uk/msd-srv/pqs/ Protein Quaternary Structure] (PQS)
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)


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{|   id="G46aa3f42de1a8"  class=" tableEdit Gene_accessions_table"   
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!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
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[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
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[http://www.ncbi.nlm.nih.gov/protein/16128695 GI:16128695]
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Escherichia coli str. K-12 substr. MG1655
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[http://www.ncbi.nlm.nih.gov/protein NCBI (Protein)] ([[NCBI (Protein)|EcoliWiki Page]])
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[http://www.ncbi.nlm.nih.gov/protein/NP_415248.1 GeneID:945323]
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Escherichia coli str. K-12 substr. MG1655
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[[ASAP]]
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ASAP:ABE-0002451
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://www.pir.uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])
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[http://www.uniprot.org/uniprot/P0ABH7 UniProtKB/Swiss-Prot:P0ABH7]
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Escherichia coli str. K-12 substr. MG1655
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[[EcoCyc]]
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[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=CITSYN-MONOMER EcoCyc:CITSYN-MONOMER]
EcoCyc:EG10402
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[[EcoGene]]
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EcoGene:EG10402
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
|-  
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[http://uniprot.org/ UniProt] ([[UniProt|EcoliWiki Page]])  
[http://www.ncbi.nlm.nih.gov/gene NCBI (Gene)] ([[NCBI (Gene)|EcoliWiki Page]])
|
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[[uniprot:P0ABH7|UniProt:P0ABH7]]
[http://www.ncbi.nlm.nih.gov/gene?term=945323 GeneID:945323]
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Escherichia coli str. K-12 substr. MG1655
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[http://pfam.sanger.ac.uk/ PFAM] ([[PFAM|EcoliWiki Page]])
[[RegulonDB]]
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[http://pfam.janelia.org/protein/P0ABH7 Pfam:P0ABH7]
RegulonDB:ECK120000395
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://www.ncbi.nlm.nih.gov/RefSeq/ RefSeq] ([[RefSeq|EcoliWiki Page]])
[[EchoBASE]]
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[http://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?db=nucleotide&val=NP_415248 RefSeq:NP_415248]
EchoBASE:EB0397
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]


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{{BacktoTop}}
{{BacktoTop}}
[[Category:Proteins]]
[[Category:Proteins]]
[[Category:GO:0005737_!_cytoplasm]][[Category:GO:0006099_!_tricarboxylic acid cycle]][[Category:GO:0009061_!_anaerobic respiration]][[Category:Products with structures in PDB]]
[[Category:Pfam:PF00285_!_Citrate synthase]]

Latest revision as of 20:29, 17 February 2015

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

GltA

Synonyms

citrate synthase[1], B0720[2][1], IcdB[2][1], GltA[2][1] , ECK0709, gluT, icdB, JW0710, b0720

Product description

citrate synthase[2][3]

Citrate synthase; hexameric[4]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004108

citrate (Si)-synthase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010953

F

Seeded from EcoCyc (v14.0)

complete

GO:0004108

citrate (Si)-synthase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.3.3.1

F

Seeded from EcoCyc (v14.0)

complete

GO:0003878

ATP citrate synthase activity

F

Missing: evidence, reference

GO:0005829

cytosol

PMID:16858726[5]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc (v14.0)

complete

GO:0006099

tricarboxylic acid cycle

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019810

P

Seeded from EcoCyc (v14.0)

complete

GO:0006099

tricarboxylic acid cycle

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0816

P

Seeded from EcoCyc (v14.0)

complete

GO:0006099

tricarboxylic acid cycle

PMID:13367004[6]

IMP: Inferred from Mutant Phenotype

P

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

PMID:16858726[5]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc (v14.0)

complete

GO:0016740

transferase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc (v14.0)

complete

GO:0044262

cellular carbohydrate metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002020

P

Seeded from EcoCyc (v14.0)

complete

GO:0044262

cellular carbohydrate metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR010953

P

Seeded from EcoCyc (v14.0)

complete

GO:0044262

cellular carbohydrate metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016141

P

Seeded from EcoCyc (v14.0)

complete

GO:0044262

cellular carbohydrate metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016142

P

Seeded from EcoCyc (v14.0)

complete

GO:0046912

transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002020

F

Seeded from EcoCyc (v14.0)

complete

GO:0046912

transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016141

F

Seeded from EcoCyc (v14.0)

complete

GO:0046912

transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR016142

F

Seeded from EcoCyc (v14.0)

complete

GO:0046912

transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019810

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

matC

PMID:16606699[7]

Experiment(s):EBI-1137791

Protein

groL

PMID:16606699[7]

Experiment(s):EBI-1137791

Protein

nadE

PMID:16606699[7]

Experiment(s):EBI-1137791

Protein

rraB

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

rho

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

iscS

PMID:19402753[8]

LCMS(ID Probability):99.2

Protein

ybgI

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

dnaN

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

rfaD

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

osmY

PMID:19402753[8]

LCMS(ID Probability):99.4

Protein

acnA

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

groS

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

tig

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

glnE

PMID:19402753[8]

LCMS(ID Probability):99.6

Protein

astC

PMID:19402753[8]

LCMS(ID Probability):99.4

edit table


Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MADTKAKLTL NGDTAVELDV LKGTLGQDVI DIRTLGSKGV FTFDPGFTST ASCESKITFI
DGDEGILLHR GFPIDQLATD SNYLEVCYIL LNGEKPTQEQ YDEFKTTVTR HTMIHEQITR
LFHAFRRDSH PMAVMCGITG ALAAFYHDSL DVNNPRHREI AAFRLLSKMP TMAAMCYKYS
IGQPFVYPRN DLSYAGNFLN MMFSTPCEPY EVNPILERAM DRILILHADH EQNASTSTVR
TAGSSGANPF ACIAAGIASL WGPAHGGANE AALKMLEEIS SVKHIPEFVR RAKDKNDSFR
LMGFGHRVYK NYDPRATVMR ETCHEVLKEL GTKDDLLEVA MELENIALND PYFIEKKLYP
NVDFYSGIIL KAMGIPSSMF TVIFAMARTV GWIAHWSEMH SDGMKIARPR QLYTGYEKRD
FKSDIKR
Length

427

Mol. Wt

48.016 kDa

pI

6.7 (calculated)

Extinction coefficient

40,340 - 41,215 (calc based on 16 Y, 3 W, and 7 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

46..409

PF00285 Citrate synthase

PMID:19920124[9]

edit table

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=gltA taxon=562,83333 </beststructure>

Models

View models at:

edit table

Structure figures

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128695

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945323

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0002451

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0ABH7

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10402

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10402

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945323

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000395

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0397

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
  6. ↑ DAVIS, BD & GILVARG, C (1956) The role of the tricarboxylic acid cycle in acetate oxidation in Escherichia coli. J. Biol. Chem. 222 307-19 PubMed
  7. ↑ 7.0 7.1 7.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  8. ↑ 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 8.11 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  9. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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