pyrH:Gene Product(s): Difference between revisions

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!|Partner Type!!Partner!!Notes!!References!!Evidence
!|Partner Type!!Partner!!Notes!!References!!Evidence
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PMID:19402753
PMID:19402753
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MALDI(Z-score):32.115364  
MALDI(Z-score):32.115364  
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Protein
Protein
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[[yhbY:Gene_Product(s)|yhbY]]
yhbY
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Protein
Protein
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[[yebT:Gene_Product(s)|yebT]]
yebT
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Protein
Protein
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[[degP:Gene_Product(s)|degP]]
degP
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Protein
Protein
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[[cadB:Gene_Product(s)|cadB]]
cadB
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Protein
Protein
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[[lpxC:Gene_Product(s)|lpxC]]
lpxC
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Protein
Protein
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[[thiE:Gene_Product(s)|thiE]]
thiE
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!|Type!!Residues!!Description!!Notes!!References
!|Type!!Residues!!Description!!Notes!!References
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View models at:
View models at:
* [http://www.proteinmodelportal.org/query/uniprot/P0A7E9 Protein Model Portal]
* [http://www.proteinmodelportal.org/query/uniprot/P0A7E9 Protein Model Portal]
* [http://bioinf.cs.ucl.ac.uk/psipred/ PSI-PRED]
* [http://bioinf.cs.ucl.ac.uk/genome3d/read?uniprot_id=P0A7E9 PSI-PRED (P0A7E9)]
* [http://spock.genes.nig.ac.jp/~genome/search.html Genomes TO Protein] (GTOP)
* [http://spock.genes.nig.ac.jp/~genome/cgi-bin/gkeytext.pl.cgi?A&QUERY1=P0A7E9 Genomes TO Protein (P0A7E9)] (GTOP)


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!|Database!!Accession!!Notes
!|Database!!Accession!!Notes
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[https://asap.ahabs.wisc.edu/asap/logon.php ASAP] ([[ASAP|EcoliWiki Page]])
[[ASAP]]
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[http://asap.ahabs.wisc.edu/asap/feature_info.php?LocationID=WIS&FeatureID=0000582&formSubmitReturn=1 ASAP:ABE-0000582]
ASAP:ABE-0000582
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Escherichia coli str. K-12 substr. MG1655  
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://ecocyc.org EcoCyc] ([[EcoCyc|EcoliWiki Page]])
[[EcoCyc]]
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[http://biocyc.org/ECOLI/NEW-IMAGE?type=NIL&object=EG11539 ECOCYC:EG11539]
EcoCyc:EG11539
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Escherichia coli str. K-12 substr. MG1655  
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[http://ecogene.org EcoGene] ([[EcoGene|EcoliWiki Page]])
[[EcoGene]]
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[http://ecogene.org/geneinfo.php?eg_id=EG11539 EcoGene:EG11539]
EcoGene:EG11539
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Escherichia coli str. K-12 substr. MG1655  
''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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Escherichia coli str. K-12 substr. MG1655  
Escherichia coli str. K-12 substr. MG1655  
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[[RegulonDB]]
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RegulonDB:ECK120001493
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]
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[[EchoBASE]]
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EchoBASE:EB1501
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''Escherichia coli'' str. K-12 substr. [[:Category:Strain:MG1655|MG1655]]


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Latest revision as of 20:22, 17 February 2015

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

PyrH

Synonyms

uridylate kinase[1], B0171[2][1], Umk[2][1], SmbA[2][1], PyrH[2][1] , ECK0170, JW0166, smbA, umk, b0171

Product description

UMPKI[2][3];

Component of uridylate kinase[2][3]

UMP kinase; hexameric; essential gene[4]

EC number (for enzymes)
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Notes

Function

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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01220

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

GO:0006221

pyrimidine nucleotide biosynthetic process

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01220

P

Seeded from EcoCyc (v14.0)

complete

GO:0006221

pyrimidine nucleotide biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011817

P

Seeded from EcoCyc (v14.0)

complete

GO:0006221

pyrimidine nucleotide biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015963

P

Seeded from EcoCyc (v14.0)

complete

GO:0006221

pyrimidine nucleotide biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0665

P

Seeded from EcoCyc (v14.0)

complete

GO:0008652

cellular amino acid biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001048

P

Seeded from EcoCyc (v14.0)

complete

GO:0009041

uridylate kinase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01220

F

Seeded from EcoCyc (v14.0)

complete

GO:0009041

uridylate kinase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR011817

F

Seeded from EcoCyc (v14.0)

complete

GO:0016301

kinase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

Seeded from EcoCyc (v14.0)

complete

GO:0016740

transferase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc (v14.0)

complete

GO:0033862

UMP kinase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR015963

F

Seeded from EcoCyc (v14.0)

complete

GO:0033862

UMP kinase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.4.22

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of uridylate kinase

could be indirect

Protein

gatZ

PMID:15690043[5]

Experiment(s):EBI-890235

Protein

recA

PMID:15690043[5]

Experiment(s):EBI-890235

Protein

rho

PMID:15690043[5]

Experiment(s):EBI-890235

Protein

tsf

PMID:16606699[6]

Experiment(s):EBI-1135778

Protein

iaaA

PMID:16606699[6]

Experiment(s):EBI-1135778

Protein

fusA

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

gatA

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

gatB

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

hns

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

degP

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

hupA

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

hupB

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

lpxC

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

groL

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplA

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplB

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplC

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplD

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplE

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplI

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplK

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplL

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplM

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplR

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplS

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplU

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplV

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplW

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rpmA

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rpmG

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rpsA

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rpsB

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rpsC

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rpsE

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rpsG

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rpsJ

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rpsP

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

secA

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

slyD

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

thiE

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

tufA

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

uspA

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

uspG

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

yfiF

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

yhbY

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

yebT

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

cadB

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

clpA

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

dnaJ

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

dnaK

PMID:15690043[5]

Experiment(s):EBI-895127

Protein

rplO

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

groL

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsA

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplA

PMID:19402753[7]

LCMS(ID Probability):99.0 MALDI(Z-score):14.894884

Protein

rpsP

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsN

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplU

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsC

PMID:19402753[7]

LCMS(ID Probability):99.0 MALDI(Z-score):13.593031

Protein

rpsF

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

gatA

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

rplB

PMID:19402753[7]

LCMS(ID Probability):99.4 MALDI(Z-score):23.928856

Protein

rpsJ

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

fusA

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

recA

PMID:19402753[7]

MALDI(Z-score):32.115364

Protein

uspA

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

gatB

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

clpA

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

rplW

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

yhbY

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

yebT

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

degP

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

cadB

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

lpxC

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

thiE

PMID:19402753[7]

LCMS(ID Probability):99.0

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
edit table


Notes

Structure and Physical Properties

[back to top]


Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MATNAKPVYK RILLKLSGEA LQGTEGFGID ASILDRMAQE IKELVELGIQ VGVVIGGGNL
FRGAGLAKAG MNRVVGDHMG MLATVMNGLA MRDALHRAYV NARLMSAIPL NGVCDSYSWA
EAISLLRNNR VVILSAGTGN PFFTTDSAAC LRGIEIEADV VLKATKVDGV FTADPAKDPT
ATMYEQLTYS EVLEKELKVM DLAAFTLARD HKLPIRVFNM NKPGALRRVV MGEKEGTLIT E
Length

241

Mol. Wt

25.97 kDa

pI

7.2 (calculated)

Extinction coefficient

12,950 - 13,200 (calc based on 5 Y, 1 W, and 2 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P0A7E9

Domain

10..219

PF00696 Amino acid kinase family

PMID:19920124[8]

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=pyrH taxon=562,83333 </beststructure>

Models

View models at:

edit table

Structure figures

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
edit table


Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16128164

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:944989

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0000582

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0A7E9

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11539

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11539

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:944989

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001493

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1501

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 5.18 5.19 5.20 5.21 5.22 5.23 5.24 5.25 5.26 5.27 5.28 5.29 5.30 5.31 5.32 5.33 5.34 5.35 5.36 5.37 5.38 5.39 5.40 5.41 5.42 5.43 5.44 5.45 5.46 5.47 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. ↑ 6.0 6.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 7.19 7.20 7.21 7.22 7.23 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

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