pyrH:Gene Product(s)
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| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
PyrH |
|---|---|
| Synonyms |
uridylate kinase[1], B0171[2][1], Umk[2][1], SmbA[2][1], PyrH[2][1] , ECK0170, JW0166, smbA, umk, b0171 |
| Product description |
Component of uridylate kinase[2][3] UMP kinase; hexameric; essential gene[4] |
| EC number (for enzymes) | |
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005524 |
ATP binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005737 |
cytoplasm |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-0086 |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006221 |
pyrimidine nucleotide biosynthetic process |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006221 |
pyrimidine nucleotide biosynthetic process |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006221 |
pyrimidine nucleotide biosynthetic process |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006221 |
pyrimidine nucleotide biosynthetic process |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0008652 |
cellular amino acid biosynthetic process |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009041 |
uridylate kinase activity |
GOA:hamap |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009041 |
uridylate kinase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016301 |
kinase activity |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0016740 |
transferase activity |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0033862 |
UMP kinase activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0033862 |
UMP kinase activity |
GOA:spec |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
Subunits of uridylate kinase |
could be indirect |
||
|
Protein |
gatZ |
Experiment(s):EBI-890235 | ||
|
Protein |
recA |
Experiment(s):EBI-890235 | ||
|
Protein |
rho |
Experiment(s):EBI-890235 | ||
|
Protein |
tsf |
Experiment(s):EBI-1135778 | ||
|
Protein |
iaaA |
Experiment(s):EBI-1135778 | ||
|
Protein |
fusA |
Experiment(s):EBI-895127 | ||
|
Protein |
gatA |
Experiment(s):EBI-895127 | ||
|
Protein |
gatB |
Experiment(s):EBI-895127 | ||
|
Protein |
hns |
Experiment(s):EBI-895127 | ||
|
Protein |
degP |
Experiment(s):EBI-895127 | ||
|
Protein |
hupA |
Experiment(s):EBI-895127 | ||
|
Protein |
hupB |
Experiment(s):EBI-895127 | ||
|
Protein |
lpxC |
Experiment(s):EBI-895127 | ||
|
Protein |
groL |
Experiment(s):EBI-895127 | ||
|
Protein |
rplA |
Experiment(s):EBI-895127 | ||
|
Protein |
rplB |
Experiment(s):EBI-895127 | ||
|
Protein |
rplC |
Experiment(s):EBI-895127 | ||
|
Protein |
rplD |
Experiment(s):EBI-895127 | ||
|
Protein |
rplE |
Experiment(s):EBI-895127 | ||
|
Protein |
rplI |
Experiment(s):EBI-895127 | ||
|
Protein |
rplK |
Experiment(s):EBI-895127 | ||
|
Protein |
rplL |
Experiment(s):EBI-895127 | ||
|
Protein |
rplM |
Experiment(s):EBI-895127 | ||
|
Protein |
rplR |
Experiment(s):EBI-895127 | ||
|
Protein |
rplS |
Experiment(s):EBI-895127 | ||
|
Protein |
rplU |
Experiment(s):EBI-895127 | ||
|
Protein |
rplV |
Experiment(s):EBI-895127 | ||
|
Protein |
rplW |
Experiment(s):EBI-895127 | ||
|
Protein |
rpmA |
Experiment(s):EBI-895127 | ||
|
Protein |
rpmG |
Experiment(s):EBI-895127 | ||
|
Protein |
rpsA |
Experiment(s):EBI-895127 | ||
|
Protein |
rpsB |
Experiment(s):EBI-895127 | ||
|
Protein |
rpsC |
Experiment(s):EBI-895127 | ||
|
Protein |
rpsE |
Experiment(s):EBI-895127 | ||
|
Protein |
rpsG |
Experiment(s):EBI-895127 | ||
|
Protein |
rpsJ |
Experiment(s):EBI-895127 | ||
|
Protein |
rpsP |
Experiment(s):EBI-895127 | ||
|
Protein |
secA |
Experiment(s):EBI-895127 | ||
|
Protein |
slyD |
Experiment(s):EBI-895127 | ||
|
Protein |
thiE |
Experiment(s):EBI-895127 | ||
|
Protein |
tufA |
Experiment(s):EBI-895127 | ||
|
Protein |
uspA |
Experiment(s):EBI-895127 | ||
|
Protein |
uspG |
Experiment(s):EBI-895127 | ||
|
Protein |
yfiF |
Experiment(s):EBI-895127 | ||
|
Protein |
yhbY |
Experiment(s):EBI-895127 | ||
|
Protein |
yebT |
Experiment(s):EBI-895127 | ||
|
Protein |
cadB |
Experiment(s):EBI-895127 | ||
|
Protein |
clpA |
Experiment(s):EBI-895127 | ||
|
Protein |
dnaJ |
Experiment(s):EBI-895127 | ||
|
Protein |
dnaK |
Experiment(s):EBI-895127 | ||
|
Protein |
rplO |
LCMS(ID Probability):99.6 | ||
|
Protein |
groL |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsA |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplA |
LCMS(ID Probability):99.0 MALDI(Z-score):14.894884 | ||
|
Protein |
rpsP |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsN |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplU |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsC |
LCMS(ID Probability):99.0 MALDI(Z-score):13.593031 | ||
|
Protein |
rpsF |
LCMS(ID Probability):99.6 | ||
|
Protein |
gatA |
LCMS(ID Probability):99.0 | ||
|
Protein |
rplB |
LCMS(ID Probability):99.4 MALDI(Z-score):23.928856 | ||
|
Protein |
rpsJ |
LCMS(ID Probability):99.6 | ||
|
Protein |
fusA |
LCMS(ID Probability):99.0 | ||
|
Protein |
recA |
MALDI(Z-score):32.115364 | ||
|
Protein |
uspA |
LCMS(ID Probability):99.0 | ||
|
Protein |
gatB |
LCMS(ID Probability):99.0 | ||
|
Protein |
clpA |
LCMS(ID Probability):99.0 | ||
|
Protein |
rplW |
LCMS(ID Probability):99.6 | ||
|
Protein |
yhbY |
LCMS(ID Probability):99.6 | ||
|
Protein |
yebT |
LCMS(ID Probability):99.0 | ||
|
Protein |
degP |
LCMS(ID Probability):99.0 | ||
|
Protein |
cadB |
LCMS(ID Probability):99.0 | ||
|
Protein |
lpxC |
LCMS(ID Probability):99.0 | ||
|
Protein |
thiE |
LCMS(ID Probability):99.0 | ||
| edit table |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MATNAKPVYK RILLKLSGEA LQGTEGFGID ASILDRMAQE IKELVELGIQ VGVVIGGGNL FRGAGLAKAG MNRVVGDHMG MLATVMNGLA MRDALHRAYV NARLMSAIPL NGVCDSYSWA EAISLLRNNR VVILSAGTGN PFFTTDSAAC LRGIEIEADV VLKATKVDGV FTADPAKDPT ATMYEQLTYS EVLEKELKVM DLAAFTLARD HKLPIRVFNM NKPGALRRVV MGEKEGTLIT E |
| Length |
241 |
| Mol. Wt |
25.97 kDa |
| pI |
7.2 (calculated) |
| Extinction coefficient |
12,950 - 13,200 (calc based on 5 Y, 1 W, and 2 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 5.18 5.19 5.20 5.21 5.22 5.23 5.24 5.25 5.26 5.27 5.28 5.29 5.30 5.31 5.32 5.33 5.34 5.35 5.36 5.37 5.38 5.39 5.40 5.41 5.42 5.43 5.44 5.45 5.46 5.47 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 6.0 6.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 7.19 7.20 7.21 7.22 7.23 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0000166 ! nucleotide binding
- GO:0005524 ! ATP binding
- GO:0005737 ! cytoplasm
- GO:0006221 ! pyrimidine nucleotide biosynthetic process
- GO:0008652 ! cellular amino acid biosynthetic process
- GO:0009041 ! uridylate kinase activity
- GO:0016301 ! kinase activity
- GO:0016740 ! transferase activity
- GO:0033862 ! UMP kinase activity
- Proteins
