ypdE:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YpdE

Synonyms

predicted peptidase[1], B2384[2][1], YpdE[2][1] , ECK2380, JW2381, b2384

Product description

broad-specificity examinopeptidase[2][3]

Aminopeptidase[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004177

aminopeptidase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0031

F

Seeded from EcoCyc (v14.0)

complete

GO:0008233

peptidase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0645

F

Seeded from EcoCyc (v14.0)

complete

GO:0008237

metallopeptidase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0482

F

Seeded from EcoCyc (v14.0)

complete

GO:0016787

hydrolase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded from EcoCyc (v14.0)

complete

GO:0004177

aminopeptidase activity

PMID:15901689[5]

IDA: Inferred from Direct Assay

F

complete

GO:0008237

metallopeptidase activity

PMID:15901689[5]

IDA: Inferred from Direct Assay

F

Fig 5b: YpdE activity dependent on presence of divalent metal ions

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

nadE

PMID:16606699[6]

Experiment(s):EBI-1142702

Protein

hflB

PMID:16606699[6]

Experiment(s):EBI-1142702

Protein

moeB

PMID:16606699[6]

Experiment(s):EBI-1142702

Protein

yfdZ

PMID:16606699[6]

Experiment(s):EBI-1142702

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MDLSLLKALS EADAIASSEQ EVRQILLEEA DRLQKEVRFD GLGSVLIRLN ESTGPKVMIC
AHMDEVGFMV RSISREGAID VLPVGNVRMA ARQLQPVRIT TREECKIPGL LDGDRQGNDV
SAMRVDIGAR SYDEVMQAGI RPGDRVTFDT TFQVLPHQRV MGKAFDDRLG CYLLVTLLRE
LHDAELPAEV WLVASSSEEV GLRGGQTATR AVSPDVAIVL DTACWAKNFD YGAANHRQIG
NGPMLVLSDK SLIAPPKLTA WVETVAAEIG VPLQADMFSN GGTDGGAVHL TGTGVPTVVM
GPATRHGHCA ASIADCRDIL QMQQLLSALI QRLTRETVVQ LTDFR
Length

345

Mol. Wt

37.408 kDa

pI

5.1 (calculated)

Extinction coefficient

20,970 - 21,720 (calc based on 3 Y, 3 W, and 6 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

43..325

PF05343 M42 glutamyl aminopeptidase

PMID:19920124[7]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=ypdE taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130316

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946848

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0007864

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P77585

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G7247

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG14152

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946848

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120003822

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB3904

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 Zheng, Y et al. (2005) Characterization of two new aminopeptidases in Escherichia coli. J. Bacteriol. 187 3671-7 PubMed
  6. 6.0 6.1 6.2 6.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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