yebA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

YebA

Synonyms

predicted peptidase[1], YebA[2][1], B1856[2][1] , ECK1857, JW5304, b1856

Product description

conserved protein[2][3]

Putative metalloprotease, function unknown; M37 family[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000920

cytokinetic cell separation

PMID:19525345[5]

IGI: Inferred from Genetic Interaction

UniProtKB:P0ADA3 UniProtKB:P37690 UniProtKB:Q46798


P

Seeded from EcoCyc (v14.0)

complete

GO:0004222

metalloendopeptidase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002886

F

Seeded from EcoCyc (v14.0)

complete

GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0006508

proteolysis

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002886

P

Seeded from EcoCyc (v14.0)

complete

GO:0007047

cellular cell wall organization

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0961

P

Seeded from EcoCyc (v14.0)

complete

GO:0008233

peptidase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0645

F

Seeded from EcoCyc (v14.0)

complete

GO:0008237

metallopeptidase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0482

F

Seeded from EcoCyc (v14.0)

complete

GO:0008270

zinc ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0862

F

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0812

C

Seeded from EcoCyc (v14.0)

complete

GO:0016021

integral to membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-9904

C

Seeded from EcoCyc (v14.0)

complete

GO:0016787

hydrolase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0378

F

Seeded from EcoCyc (v14.0)

complete

GO:0016998

cell wall macromolecule catabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002482

P

Seeded from EcoCyc (v14.0)

complete

GO:0016998

cell wall macromolecule catabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018392

P

Seeded from EcoCyc (v14.0)

complete

GO:0046872

metal ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded from EcoCyc (v14.0)

complete

GO:0000920

cytokinetic cell separation

PMID:19525345[5]

IGI: Inferred from Genetic Interaction

UniProtKB:P37690


P

complete

GO:0000920

cytokinetic cell separation

PMID:19525345[5]

IGI: Inferred from Genetic Interaction

UniProtKB:P0ADA3 UniProtKB:P37690 UniProtKB:Q46798


P

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MLGSLTVLTL AVAVWRPYVY HRDATPIVKT IELEQNEIRS LLPEASEPID QAAQEDEAIP
QDELDDKIAG EAGVHEYVVS TGDTLSSILN QYGIDMGDIT QLAAADKELR NLKIGQQLSW
TLTADGELQR LTWEVSRRET RTYDRTAANG FKMTSEMQQG EWVNNLLKGT VGGSFVASAR
NAGLTSAEVS AVIKAMQWQM DFRKLKKGDE FAVLMSREML DGKREQSQLL GVRLRSEGKD
YYAIRAEDGK FYDRNGTGLA KGFLRFPTAK QFRISSNFNP RRTNPVTGRV APHRGVDFAM
PQGTPVLSVG DGEVVVAKRS GAAGYYVAIR HGRSYTTRYM HLRKILVKPG QKVKRGDRIA
LSGNTGRSTG PHLHYEVWIN QQAVNPLTAK LPRTEGLTGS DRREFLAQAK EIVPQLRFD
Length

419

Mol. Wt

46.657 kDa

pI

9.7 (calculated)

Extinction coefficient

52,370 (calc based on 13 Y, 6 W, and 0 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

312..407

PF01551 Peptidase family M23

PMID:19920124[6]

Domain

94..176

PF04225 Opacity-associated protein A LysM-like domain

PMID:19920124[6]

Domain

10..40

PF08525 Opacity-associated protein A N-terminal motif

PMID:19920124[6]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=yebA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111345

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0006189

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0AFS9

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10013

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10013

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946376

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000011

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946376

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0013

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 Uehara, T et al. (2009) LytM-domain factors are required for daughter cell separation and rapid ampicillin-induced lysis in Escherichia coli. J. Bacteriol. 191 5094-107 PubMed
  6. ↑ 6.0 6.1 6.2 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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