tdcB:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

TdcB

Synonyms

catabolic threonine dehydratase, PLP-dependent[1], B3117[2][1], Tdc[2][1], TdcB[2][1] , ECK3106, JW3088, b3117

Product description

TdcB[2][3];

Component of threonine dehydratase (catabolic)[2][3]

Threonine dehydratase[4]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0005737

cytoplasm

PMID:3540965[5]

IC: Inferred by Curator

C

Missing: with/from

GO:0004793

threonine aldolase activity

PMID:3540965[5]

IDA: Inferred from Direct Assay

F

complete

GO:0006567

threonine catabolic process

PMID:6751404[6]

IDA: Inferred from Direct Assay

P

complete

GO:0016597

amino acid binding

PMID:3540965[5]

IDA: Inferred from Direct Assay

F

complete

GO:0030170

pyridoxal phosphate binding

PMID:6751404[6]

IDA: Inferred from Direct Assay

F

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of threonine dehydratase (catabolic)

could be indirect

Protein

yijP

PMID:16606699[7]

Experiment(s):EBI-1144834

Protein

yqjG

PMID:16606699[7]

Experiment(s):EBI-1144834
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MHITYDLPVA IDDIIEAKQR LAGRIYKTGM PRSNYFSERC KGEIFLKFEN MQRTGSFKIR
GAFNKLSSLT DAEKRKGVVA CSAGNHAQGV SLSCAMLGID GKVVMPKGAP KSKVAATCDY
SAEVVLHGDN FNDTIAKVSE IVEMEGRIFI PPYDDPKVIA GQGTIGLEIM EDLYDVDNVI
VPIGGGGLIA GIAVAIKSIN PTIRVIGVQS ENVHGMAASF HSGEITTHRT TGTLADGCDV
SRPGNLTYEI VRELVDDIVL VSEDEIRNSM IALIQRNKVV TEGAGALACA ALLSGKLDQY
IQNRKTVSII SGGNIDLSRV SQITGFVDA
Length

329

Mol. Wt

35.232 kDa

pI

6.0 (calculated)

Extinction coefficient

11,920 - 12,670 (calc based on 8 Y, 0 W, and 6 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

22..312

PF00291 Pyridoxal-phosphate dependent enzyme

PMID:19920124[8]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=tdcB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131010

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947633

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0010249

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0AGF6

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10990

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10990

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947633

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000979

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0983

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 Datta, P et al. (1987) Covalent structure of biodegradative threonine dehydratase of Escherichia coli: homology with other dehydratases. Proc. Natl. Acad. Sci. U.S.A. 84 393-7 PubMed
  6. ↑ 6.0 6.1 Kim, SS & Datta, P (1982) Chemical characterization of biodegradative threonine dehydratases from two enteric bacteria. Biochim. Biophys. Acta 706 27-35 PubMed
  7. ↑ 7.0 7.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  8. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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