bamE:Gene Product(s)
{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>
| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
BamE |
|---|---|
| Synonyms |
small membrane lipoprotein[1], B2617[2][1], SmqA[2][1], BamE[2][1], BamE [3] , ECK2613, JW2598, smpA, smqA, b2617 |
| Product description |
BamE small membrane protein A[2][4] Component of Outer Membrane Protein Assembly Complex[4] Stabilizes BamABCD OM biogenesis complex; member of a BamABCDBamE multiprotein complex; probable lipoprotein, Cys conserved[3] |
| EC number (for enzymes) |
|
| edit table |
<protect></protect>
Notes
BamA (SmpA) is non-essential [5]
Function
<protect>
Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005886 |
plasma membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0009279 |
cell outer membrane |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005515 |
protein binding |
IPI: Inferred from Physical Interaction |
EcoliWiki:yaeT
|
F |
complete | |||
| GO:0031225 |
anchored to membrane |
IEA: Inferred from Electronic Annotation |
SP_SL:SL-9901 |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0045203 |
integral to cell outer membrane |
IGI: Inferred from Genetic Interaction |
EcoliWiki:yaeT
|
C |
complete | |||
| GO:0016020 |
membrane |
IDA: Inferred from Direct Assay |
C |
complete | ||||
| GO:0043165 |
Gram-negative-bacterium-type cell outer membrane assembly |
IGI: Inferred from Genetic Interaction |
EcoliWiki:yaeT
|
P |
complete | |||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
BamA (yaeT) |
BamE (SmpA) binds BamA via the BamCDE sub-complex (NlpB-YfiO-SmpA). Interactions between BamA-BamCDE are independent of the interaction between BamA-BamB (YfgL) [6] |
||
|
Protein |
BamC (nlpB) |
BamE (SmpA) binds BamC as part of the BamCDE sub-complex (NlpB-YfiO-SmpA). [6] |
||
|
Protein |
BamD (yfiO) |
BamE (SmpA) binds BamD as part of the BamCDE sub-complex (NlpB-YfiO-SmpA). [6] |
| |
| edit table |
</protect>
Notes
SmpA is a component of the YaeT complex, which is involved in assembling outer membrane proteins [5]
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
|
Outer membrane |
| |||
| edit table |
<protect></protect>
Notes
Structure and Physical Properties
<protect>
Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MSDPFGTNTW FYVFRQQPGH EGVTQQTLTL TFNSSGVLTN IDNKPALSGN |
| Length |
50 |
| Mol. Wt |
5.517 kDa |
| pI |
5.6 (calculated) |
| Extinction coefficient |
6,990 (calc based on 1 Y, 1 W, and C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
<protect></protect>
Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
RegulonDB: |
Escherichia coli str. K-12 substr. MG1655 | |
|
EchoBASE: |
Escherichia coli str. K-12 substr. MG1655 | |
| edit table |
<protect></protect>
Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 4.0 4.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 5.0 5.1 Sklar, JG et al. (2007) Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 104 6400-5 PubMed
- ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 Sklar, JG et al. (2007) Lipoprotein SmpA is a component of the YaeT complex that assembles outer membrane proteins in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 104 6400-5 PubMed
- ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0005886 ! plasma membrane
- GO:0009279 ! cell outer membrane
- GO:0005515 ! protein binding
- GO:0031225 ! anchored component of membrane
- GO:0045203 ! integral component of cell outer membrane
- GO:0016020 ! membrane
- GO:0043165 ! Gram-negative-bacterium-type cell outer membrane assembly
- Proteins
- Complex:Outer Membrane Protein Assembly Complex
- Pfam:PF04355 ! SmpA / OmlA family
