sdaA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

SdaA

Synonyms

L-serine deaminase I[1], B1814[2][1], SdaA[2][1], SDH1[2][1], L-SD[2][1], L-threonine deaminase I[2][1], L-serine dehydratase 1[2][1], SDH-1[2][1], L-SD1[2][1], L-hydroxyaminoacid dehydratase 1[2][1], L-serine deaminase 1[2][1], L-serine hydro-lyase 1 (deaminating)[2][1] , ECK1812, JW1803, b1814

Product description

LSERINEDEAM1[2][3]

L-Serine deaminase I; L-SD2[4]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0003941

L-serine ammonia-lyase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004644

F

Seeded from EcoCyc (v14.0)

complete

GO:0003941

L-serine ammonia-lyase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005130

F

Seeded from EcoCyc (v14.0)

complete

GO:0003941

L-serine ammonia-lyase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005131

F

Seeded from EcoCyc (v14.0)

complete

GO:0003941

L-serine ammonia-lyase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:4.3.1.17

F

Seeded from EcoCyc (v14.0)

complete

GO:0005506

iron ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0408

F

Seeded from EcoCyc (v14.0)

complete

GO:0006094

gluconeogenesis

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004644

P

Seeded from EcoCyc (v14.0)

complete

GO:0006094

gluconeogenesis

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005130

P

Seeded from EcoCyc (v14.0)

complete

GO:0006094

gluconeogenesis

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005131

P

Seeded from EcoCyc (v14.0)

complete

GO:0006094

gluconeogenesis

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0312

P

Seeded from EcoCyc (v14.0)

complete

GO:0046872

metal ion binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0479

F

Seeded from EcoCyc (v14.0)

complete

GO:0051536

iron-sulfur cluster binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0411

F

Seeded from EcoCyc (v14.0)

complete

GO:0051539

4 iron, 4 sulfur cluster binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005130

F

Seeded from EcoCyc (v14.0)

complete

GO:0051539

4 iron, 4 sulfur cluster binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005131

F

Seeded from EcoCyc (v14.0)

complete

GO:0051539

4 iron, 4 sulfur cluster binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0004

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

ydiU

PMID:16606699[5]

Experiment(s):EBI-1140917

Protein

prpD

PMID:16606699[5]

Experiment(s):EBI-1140917

Protein

zwf

PMID:16606699[5]

Experiment(s):EBI-1140917
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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MISLFDMFKV GIGPSSSHTV GPMKAGKQFV DDLVEKGLLD SVTRVAVDVY GSLSLTGKGH
HTDIAIIMGL AGNEPATVDI DSIPGFIRDV EERERLLLAQ GRHEVDFPRD NGMRFHNGNL
PLHENGMQIH AYNGDEVVYS KTYYSIGGGF IVDEEHFGQD AANEVSVPYP FKSATELLAY
CNETGYSLSG LAMQNELALH SKKEIDEYFA HVWQTMQACI DRGMNTEGVL PGPLRVPRRA
SALRRMLVSS DKLSNDPMNV IDWVNMFALA VNEENAAGGR VVTAPTNGAC GIVPAVLAYY
DHFIESVSPD IYTRYFMAAG AIGALYKMNA SISGAEVGCQ GEVGVACSMA AAGLAELLGG
SPEQVCVAAE IGMEHNLGLT CDPVAGQVQV PCIERNAIAS VKAINAARMA LRRTSAPRVS
LDKVIETMYE TGKDMNAKYR ETSRGGLAIK VQCD
Length

454

Mol. Wt

48.906 kDa

pI

5.1 (calculated)

Extinction coefficient

34,840 - 35,965 (calc based on 16 Y, 2 W, and 9 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

182..450

PF03313 Serine dehydratase alpha chain

PMID:19920124[6]

Domain

3..159

PF03315 Serine dehydratase beta chain

PMID:19920124[6]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=sdaA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129768

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946331

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0006039

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P16095

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10930

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10930

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946331

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000919

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0923

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.00 2.01 2.02 2.03 2.04 2.05 2.06 2.07 2.08 2.09 2.10 2.11 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 5.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. ↑ 6.0 6.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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