rluB:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

RluB

Synonyms

23S rRNA pseudouridylate synthase[1], B1269[2][1], RluB[2][1], YciL[2][1] , ECK1263, JW1261, yciL, b1269

Product description

23S rRNA pseudouridine synthase[2][3]

23S rRNA U2605 pseudouridine synthase[4]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0003723

RNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000748

F

Seeded from EcoCyc (v14.0)

complete

GO:0003723

RNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002942

F

Seeded from EcoCyc (v14.0)

complete

GO:0003723

RNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006145

F

Seeded from EcoCyc (v14.0)

complete

GO:0003723

RNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018496

F

Seeded from EcoCyc (v14.0)

complete

GO:0003723

RNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020103

F

Seeded from EcoCyc (v14.0)

complete

GO:0003723

RNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0694

F

Seeded from EcoCyc (v14.0)

complete

GO:0009982

pseudouridine synthase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006145

F

Seeded from EcoCyc (v14.0)

complete

GO:0009982

pseudouridine synthase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR020103

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

rplC

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889536

Protein

rplD

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

rplE

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

rplF

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

rplI

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889536

Protein

rplM

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889536

Protein

rpsA

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889536

Protein

rpsB

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

rpsC

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

rpsD

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

rpsE

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889536

Protein

rpsG

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889536

Protein

rpsJ

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889536

Protein

rpsM

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

srmB

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889906, EBI-889536

Protein

rnr

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889536

Protein

ybhF

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

ycbY

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

ygiF

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889536

Protein

yhiR

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889536

Protein

aceE

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

aidB

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

hrpA

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889536

Protein

pssA

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

rplA

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-889536

Protein

rplB

PMID:15690043[5]

Experiment(s):EBI-878697

Protein

pnp

PMID:15690043[5]

Experiment(s):EBI-878697, EBI-883913

Protein

yciK

PMID:16606699[6]

Experiment(s):EBI-1139392

Protein

rplD

PMID:16606699[6]

Experiment(s):EBI-1139392

Protein

trpH

PMID:16606699[6]

Experiment(s):EBI-1139392

Protein

matC

PMID:16606699[6]

Experiment(s):EBI-1139392

Protein

yhcA

PMID:16606699[6]

Experiment(s):EBI-1139392

Protein

alaS

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rplS

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rplU

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rplV

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rplX

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rplY

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rpmB

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rpsF

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rpsN

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rpsP

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rpsR

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rpsU

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

yhbP

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

yhiN

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

yibL

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rluE

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

rpsT

PMID:15690043[5]

Experiment(s):EBI-889536

Protein

alaS

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsJ

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):10.392078

Protein

rpmB

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsN

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

hupA

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):8.532802

Protein

rpsP

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplY

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplS

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):14.060385

Protein

hupB

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsT

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplU

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsF

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplP

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):2.924285

Protein

rpsM

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):13.939772

Protein

rpsA

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):23.063409

Protein

rplM

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):26.375559

Protein

rpsS

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplI

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):27.796292

Protein

rpsC

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):39.720713

Protein

rplE

PMID:19402753[7]

MALDI(Z-score):24.175743

Protein

rplA

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):49.687349

Protein

ihfA

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsD

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):33.716981

Protein

malP

PMID:19402753[7]

MALDI(Z-score):25.062476

Protein

rplX

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):9.289736

Protein

rplB

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):38.386342

Protein

yhiN

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplT

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsR

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplO

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):9.822047

Protein

rplD

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):11.464963

Protein

rplR

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsU

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

yhbY

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):29.921344

Protein

rplF

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):21.056102

Protein

yeeX

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):27.920160

Protein

rplQ

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):8.078623

Protein

yihI

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

infC

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):9.079176

Protein

ygiF

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):38.545635

Protein

aidB

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):7.165941

Protein

yfiF

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):39.439746

Protein

hfq

PMID:19402753[7]

LCMS(ID Probability):91.3 MALDI(Z-score):34.025282

Protein

srmB

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):27.618726

Protein

ybcJ

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):36.425657

Protein

rnr

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):28.384439

Protein

pssA

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):27.564573

Protein

yhbP

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

dapF

PMID:19402753[7]

LCMS(ID Probability):99.0 MALDI(Z-score):4.519301

Protein

hrpA

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):18.667898

Protein

yibL

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):11.691034

Protein

rlmL

PMID:19402753[7]

MALDI(Z-score):29.013329

Protein

rluC

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):38.535535

Protein

yhiR

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):39.378168

Protein

rluE

PMID:19402753[7]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MSEKLQKVLA RAGHGSRREI ESIIEAGRVS VDGKIAKLGD RVEVTPGLKI RIDGHLISVR
ESAEQICRVL AYYKPEGELC TRNDPEGRPT VFDRLPKLRG ARWIAVGRLD VNTCGLLLFT
TDGELANRLM HPSREVEREY AVRVFGQVDD AKLRDLSRGV QLEDGPAAFK TIKFSGGEGI
NQWYNVTLTE GRNREVRRLW EAVGVQVSRL IRVRYGDIPL PKGLPRGGWT ELDLAQTNYL
RELVELPPET SSKVAVEKDR RRMKANQIRR AVKRHSQVSG GRRSGGRNNN G
Length

291

Mol. Wt

32.711 kDa

pI

10.4 (calculated)

Extinction coefficient

30,940 - 31,315 (calc based on 6 Y, 4 W, and 3 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

3..57

PF01479 S4 domain

PMID:19920124[8]

Domain

68..202

PF00849 RNA pseudouridylate synthase

PMID:19920124[8]

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=rluB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129230

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:945840

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0004259

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P37765

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12433

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12433

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:945840

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002288

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2329

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 5.18 5.19 5.20 5.21 5.22 5.23 5.24 5.25 5.26 5.27 5.28 5.29 5.30 5.31 5.32 5.33 5.34 5.35 5.36 5.37 5.38 5.39 5.40 5.41 5.42 5.43 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 7.19 7.20 7.21 7.22 7.23 7.24 7.25 7.26 7.27 7.28 7.29 7.30 7.31 7.32 7.33 7.34 7.35 7.36 7.37 7.38 7.39 7.40 7.41 7.42 7.43 7.44 7.45 7.46 7.47 7.48 7.49 7.50 7.51 7.52 7.53 7.54 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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