pabC:Gene Product(s)

From EcoliWiki
Jump to: navigation, search

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

PabC

Synonyms

4-amino-4-deoxychorismate lyase component of para-aminobenzoate synthase multienzyme complex[1], B1096[2][1], PabC[2][1] , ECK1082, JW1082, b1096

Product description

pabC[2][3];

Component of aminodeoxychorismate lyase[2][3]; para-aminobenzoate synthase multi-enzyme complex[2][3]

Sulfonamide resistance; aminodeoxychorismate lyase[4]

EC number (for enzymes)

<protect></protect>

Notes

Function

[back to top]


<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0003824

catalytic activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001544

F

Seeded from EcoCyc (v14.0)

complete

GO:0003824

catalytic activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018300

F

Seeded from EcoCyc (v14.0)

complete

GO:0008152

metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001544

P

Seeded from EcoCyc (v14.0)

complete

GO:0008152

metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018300

P

Seeded from EcoCyc (v14.0)

complete

GO:0008696

4-amino-4-deoxychorismate lyase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017824

F

Seeded from EcoCyc (v14.0)

complete

GO:0008696

4-amino-4-deoxychorismate lyase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:4.1.3.38

F

Seeded from EcoCyc (v14.0)

complete

GO:0016829

lyase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0456

F

Seeded from EcoCyc (v14.0)

complete

GO:0030170

pyridoxal phosphate binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017824

F

Seeded from EcoCyc (v14.0)

complete

GO:0046656

folic acid biosynthetic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR017824

P

Seeded from EcoCyc (v14.0)

complete

GO:0046656

folic acid biosynthetic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0289

P

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of aminodeoxychorismate lyase

could be indirect

Protein

talA

PMID:16606699[5]

Experiment(s):EBI-1138845

Protein

tmk

PMID:16606699[5]

Experiment(s):EBI-1138845

Protein

pflA

PMID:16606699[5]

Experiment(s):EBI-1138845

Protein

ydfE

PMID:16606699[5]

Experiment(s):EBI-1138845

Protein

rpsD

PMID:16606699[5]

Experiment(s):EBI-1138845

Protein

eno

PMID:19402753[6]

LCMS(ID Probability):99.5

Protein

Subunits of para-aminobenzoate synthase multi-enzyme complex

could be indirect


</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

<protect></protect>

Notes

Structure and Physical Properties

[back to top]


<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MFLINGHKQE SLAVSDRATQ FGDGCFTTAR VIDGKVSLLS AHIQRLQDAC QRLMISCDFW
PQLEQEMKTL AAEQQNGVLK VVISRGSGGR GYSTLNSGPA TRILSVTAYP AHYDRLRNEG
ITLALSPVRL GRNPHLAGIK HLNRLEQVLI RSHLEQTNAD EALVLDSEGW VTECCAANLF
WRKGNVVYTP RLDQAGVNGI MRQFCIRLLA QSSYQLVEVQ ASLEESLQAD EMVICNALMP
VMPVCACGDV SFSSATLYEY LAPLCERPN
Length

269

Mol. Wt

29.714 kDa

pI

6.5 (calculated)

Extinction coefficient

26,930 - 28,180 (calc based on 7 Y, 3 W, and 10 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

37..267

PF01063 Aminotransferase class IV

PMID:19920124[7]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=pabC taxon=562,83333 </beststructure>

Models

View models at:

</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

<protect></protect>

Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129059

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946647

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0003709

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P28305

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11493

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11493

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946647

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001449

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1456

Escherichia coli str. K-12 substr. MG1655

<protect></protect>

Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 5.3 5.4 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  7. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

[back to top]