obgE:Gene Product(s)

From EcoliWiki
Jump to: navigation, search

{{#css:Suppresslinks.css}}<css>h1 .editsection { display:none;} h2 .editsection { display:none;}</css>

Quickview   Gene   Gene Product(s)   Expression   Evolution   On One Page    
Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

ObgE

Synonyms

GTPase involved in cell partioning and DNA repair[1], B3183[2][1], YhbZ[2][1], CgtA[2][1], ObgE[2][1], Obg[2][1] , cgtA, ECK3172, JW3150, obg, yhbZ, b3183

Product description

GTPase involved in DNA replication and ribosome assembly[2][3]

DNA-binding GTPase involved in cell partioning and DNA repair; involved in ribosome assembly; GTP-bound form associates with 50S ribosomal subunits[4]

EC number (for enzymes)


<protect></protect>

Notes

Function

[back to top]


<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc (v14.0)

complete

GO:0003723

RNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0694

F

Seeded from EcoCyc (v14.0)

complete

GO:0003924

GTPase activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01454

F

Seeded from EcoCyc (v14.0)

complete

GO:0005525

GTP binding

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_01454

F

Seeded from EcoCyc (v14.0)

complete

GO:0005525

GTP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR002917

F

Seeded from EcoCyc (v14.0)

complete

GO:0005525

GTP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR005225

F

Seeded from EcoCyc (v14.0)

complete

GO:0005525

GTP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006073

F

Seeded from EcoCyc (v14.0)

complete

GO:0005525

GTP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006074

F

Seeded from EcoCyc (v14.0)

complete

GO:0005525

GTP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006169

F

Seeded from EcoCyc (v14.0)

complete

GO:0005525

GTP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0342

F

Seeded from EcoCyc (v14.0)

complete

GO:0019843

rRNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0699

F

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

fbaB

PMID:15690043[5]

Experiment(s):EBI-881925

Protein

rluD

PMID:15690043[5]

Experiment(s):EBI-881925

Protein

ydiH

PMID:15690043[5]

Experiment(s):EBI-889421

Protein

pepE

PMID:15690043[5]

Experiment(s):EBI-889421

Protein

prlC

PMID:15690043[5]

Experiment(s):EBI-889421

Protein

rplL

PMID:15690043[5]

Experiment(s):EBI-889421

Protein

rpoA

PMID:15690043[5]

Experiment(s):EBI-889421

Protein

rpsE

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

btuE

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

yaeQ

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

yhbT

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

rpsC

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

sufE

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

yihI

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

ygiT

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

rplQ

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

rplB

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

gloA

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

rplO

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

hns

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

rplE

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

rpsI

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

yhbH

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

rpsD

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

aroD

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

slyD

PMID:16606699[6]

Experiment(s):EBI-1145063

Protein

fbaB

PMID:19402753[7]

MALDI(Z-score):17.053160

Protein

ydiH

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

rluD

PMID:19402753[7]

MALDI(Z-score):17.053160

Protein

pepE

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

prlC

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

rplL

PMID:19402753[7]

LCMS(ID Probability):99.6

</protect>

Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

cytoplasm


<protect></protect>

Notes

Structure and Physical Properties

[back to top]


<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MKFVDEASIL VVAGDGGNGC VSFRREKYIP KGGPDGGDGG DGGDVWMEAD ENLNTLIDYR
FEKSFRAERG QNGASRDCTG KRGKDVTIKV PVGTRVIDQG TGETMGDMTK HGQRLLVAKG
GWHGLGNTRF KSSVNRTPRQ KTNGTPGDKR ELLLELMLLA DVGMLGMPNA GKSTFIRAVS
AAKPKVADYP FTTLVPSLGV VRMDNEKSFV VADIPGLIEG AAEGAGLGIR FLKHLERCRV
LLHLIDIDPI DGTDPVENAR IIISELEKYS QDLATKPRWL VFNKIDLLDK VEAEEKAKAI
AEALGWEDKY YLISAASGLG VKDLCWDVMT FIIENPVVQA EEAKQPEKVE FMWDDYHRQQ
LEEIAEEDDE DWDDDWDEDD EEGVEFIYKR
Length

390

Mol. Wt

43.286 kDa

pI

4.6 (calculated)

Extinction coefficient

55,920 - 56,420 (calc based on 8 Y, 8 W, and 4 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

3..158

PF01018 GTP1/OBG

PMID:19920124[8]

Domain

171..284

PF01926 GTPase of unknown function

PMID:19920124[8]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=obgE taxon=562,83333 </beststructure>

Models

View models at:

</protect>

Structure figures

<protect>

</protect>

Notes

Gene Product Resources

[back to top]


See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

<protect></protect>

Notes

Accessions in Other Databases

[back to top]


See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131073

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947694

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0010462

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P42641

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G7656

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12795

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947694

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120004206

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2647

Escherichia coli str. K-12 substr. MG1655

<protect></protect>

Notes

Links

[back to top]




References

[back to top]


See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.0 5.1 5.2 5.3 5.4 5.5 5.6 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 6.13 6.14 6.15 6.16 6.17 6.18 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. 7.0 7.1 7.2 7.3 7.4 7.5 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

[back to top]