nusG:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

NusG

Synonyms

transcription termination factor[1], B3982[2][1], NusG[2][1] , ECK3973, JW3945, b3982

Product description

transcription termination factor NusG[2][3]

Stabilizes phage lambda protein N-NusA-RNAP antitermination complex[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003711

transcription elongation regulator activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001062

F

Seeded from EcoCyc (v14.0)

complete

GO:0003711

transcription elongation regulator activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006645

F

Seeded from EcoCyc (v14.0)

complete

GO:0006350

transcription

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc (v14.0)

complete

GO:0006353

transcription termination

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0806

P

Seeded from EcoCyc (v14.0)

complete

GO:0006355

regulation of transcription, DNA-dependent

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001062

P

Seeded from EcoCyc (v14.0)

complete

GO:0031564

transcription antitermination

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0889

P

Seeded from EcoCyc (v14.0)

complete

GO:0032968

positive regulation of RNA elongation from RNA polymerase II promoter

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006645

P

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

macA

PMID:15690043[5]

Experiment(s):EBI-886705

Protein

arnA

PMID:15690043[5]

Experiment(s):EBI-886705

Protein

dnaJ

PMID:15690043[5]

Experiment(s):EBI-886705

Protein

rapA

PMID:15690043[5]

Experiment(s):EBI-886705

Protein

mreB

PMID:15690043[5]

Experiment(s):EBI-886705, EBI-893751

Protein

pssA

PMID:15690043[5]

Experiment(s):EBI-886705

Protein

rho

PMID:15690043[5]

Experiment(s):EBI-886705, EBI-891277, EBI-893067

Protein

rplB

PMID:15690043[5]

Experiment(s):EBI-886705

Protein

rplE

PMID:15690043[5]

Experiment(s):EBI-886705

Protein

rpoA

PMID:15690043[5]

Experiment(s):EBI-886705, EBI-879354, EBI-883271, EBI-893067

Protein

rpoB

PMID:15690043[5]

Experiment(s):EBI-886705, EBI-879304, EBI-883170

Protein

rpoC

PMID:15690043[5]

Experiment(s):EBI-886705, EBI-879261, EBI-883046

Protein

rpsC

PMID:15690043[5]

Experiment(s):EBI-886705

Protein

rpsE

PMID:15690043[5]

Experiment(s):EBI-886705, EBI-893067

Protein

rpsJ

PMID:15690043[5]

Experiment(s):EBI-886705, EBI-893067

Protein

secA

PMID:15690043[5]

Experiment(s):EBI-886705

Protein

sgbH

PMID:15690043[5]

Experiment(s):EBI-886705

Protein

yacL

PMID:15690043[5]

Experiment(s):EBI-886705, EBI-879082, EBI-882523, EBI-893067

Protein

deaD

PMID:15690043[5]

Experiment(s):EBI-886705

Protein

rpoA

PMID:16606699[6]

Experiment(s):EBI-1147147

Protein

rpoC

PMID:16606699[6]

Experiment(s):EBI-1147147

Protein

iscS

PMID:16606699[6]

Experiment(s):EBI-1147147

Protein

rho

PMID:16606699[6]

Experiment(s):EBI-1147147

Protein

rpoB

PMID:16606699[6]

Experiment(s):EBI-1147147

Protein

mukB

PMID:16606699[6]

Experiment(s):EBI-1147147

Protein

sucB

PMID:16606699[6]

Experiment(s):EBI-1147147

Protein

ynaA

PMID:16606699[6]

Experiment(s):EBI-1147147

Protein

wza

PMID:16606699[6]

Experiment(s):EBI-1147147

Protein

rapA

PMID:16606699[6]

Experiment(s):EBI-1147147

Protein

kefA

PMID:15690043[5]

Experiment(s):EBI-893067

Protein

rplD

PMID:15690043[5]

Experiment(s):EBI-893067

Protein

rplL

PMID:15690043[5]

Experiment(s):EBI-893067

Protein

rplV

PMID:15690043[5]

Experiment(s):EBI-893067

Protein

rplW

PMID:15690043[5]

Experiment(s):EBI-893067

Protein

rpmB

PMID:15690043[5]

Experiment(s):EBI-893067

Protein

rpsB

PMID:15690043[5]

Experiment(s):EBI-893067

Protein

rpsF

PMID:15690043[5]

Experiment(s):EBI-893067

Protein

rpsG

PMID:15690043[5]

Experiment(s):EBI-893067

Protein

rpsN

PMID:15690043[5]

Experiment(s):EBI-893067

Protein

rpsP

PMID:15690043[5]

Experiment(s):EBI-893067

Protein

rpsH

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplP

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

gapA

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplN

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsP

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpmB

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsF

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsN

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rho

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):42.833204

Protein

dnaJ

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):22.722310

Protein

rplB

PMID:19402753[7]

LCMS(ID Probability):93.1 MALDI(Z-score):38.553054

Protein

rpsC

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):21.904713

Protein

pssA

PMID:19402753[7]

MALDI(Z-score):20.384978

Protein

rplW

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsJ

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):14.949782

Protein

rpsU

PMID:19402753[7]

LCMS(ID Probability):99.2

Protein

kefA

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplD

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

deaD

PMID:19402753[7]

MALDI(Z-score):23.328459

Protein

rapA

PMID:19402753[7]

MALDI(Z-score):18.521811

Protein

rplL

PMID:19402753[7]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MSEAPKKRWY VVQAFSGFEG RVATSLREHI KLHNMEDLFG EVMVPTEEVV EIRGGQRRKS
ERKFFPGYVL VQMVMNDASW HLVRSVPRVM GFIGGTSDRP APISDKEVDA IMNRLQQVGD
KPRPKTLFEP GEMVRVNDGP FADFNGVVEE VDYEKSRLKV SVSIFGRATP VELDFSQVEK A
Length

181

Mol. Wt

20.53 kDa

pI

6.9 (calculated)

Extinction coefficient

15,470 (calc based on 3 Y, 2 W, and 0 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P0AFG0

Domain

130..165

PF00467 KOW motif

PMID:19920124[8]

Domain

7..106

PF02357 Transcription termination factor nusG

PMID:19920124[8]

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=nusG taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16131812

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:948485

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0013026

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0AFG0

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10667

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10667

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:948485

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000660

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0661

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 5.18 5.19 5.20 5.21 5.22 5.23 5.24 5.25 5.26 5.27 5.28 5.29 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 6.4 6.5 6.6 6.7 6.8 6.9 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 7.19 7.20 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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