nusA:Gene Product(s)
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| Quickview | Gene | Gene Product(s) | Expression | Evolution | On One Page |
| Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
| Standard name |
NusA |
|---|---|
| Synonyms |
transcription termination/antitermination L factor[1], B3169[2][1], NusA[2][1] , ECK3158, JW3138, b3169 |
| Product description |
transcription termination/antitermination L factor[2][3] Transcription termination/antitermination L factor; mutant survives lambda induction[4] |
| EC number (for enzymes) |
|
| edit table |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003700 |
transcription factor activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0003723 |
RNA binding |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005515 |
protein binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0005515 |
protein binding |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006281 |
DNA repair |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006350 |
transcription |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006353 |
transcription termination |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0006950 |
response to stress |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0030528 |
transcription regulator activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0030528 |
transcription regulator activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0031554 |
regulation of transcription termination |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0031564 |
transcription antitermination |
GOA:spkw |
IEA: Inferred from Electronic Annotation |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
| GO:0031564 |
transcription antitermination |
IMP: Inferred from Mutant Phenotype |
P |
complete | ||||
| edit table |
Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
| Partner Type | Partner | Notes | References | Evidence |
|---|---|---|---|---|
|
Protein |
prsA |
Experiment(s):EBI-886823 | ||
|
Protein |
rpsD |
Experiment(s):EBI-886823 | ||
|
Protein |
rpsG |
Experiment(s):EBI-886823 | ||
|
Protein |
tufA |
Experiment(s):EBI-886823 | ||
|
Protein |
infB |
Experiment(s):EBI-886823, EBI-893117 | ||
|
Protein |
rplA |
Experiment(s):EBI-886823 | ||
|
Protein |
rplB |
Experiment(s):EBI-886823 | ||
|
Protein |
rplC |
Experiment(s):EBI-886823 | ||
|
Protein |
rplD |
Experiment(s):EBI-886823 | ||
|
Protein |
rplO |
Experiment(s):EBI-886823 | ||
|
Protein |
rplV |
Experiment(s):EBI-886823, EBI-893117 | ||
|
Protein |
rpoA |
Experiment(s):EBI-886823, EBI-879354, EBI-883271, EBI-893117 | ||
|
Protein |
rpoB |
Experiment(s):EBI-886823, EBI-879304, EBI-883170, EBI-893117 | ||
|
Protein |
rpoC |
Experiment(s):EBI-886823, EBI-879261, EBI-893117 | ||
|
Protein |
rpoH |
Experiment(s):EBI-886823 | ||
|
Protein |
rpsC |
Experiment(s):EBI-886823 | ||
|
Protein |
aceE |
Experiment(s):EBI-893117 | ||
|
Protein |
metJ |
Experiment(s):EBI-893117 | ||
|
Protein |
pstS |
Experiment(s):EBI-893117 | ||
|
Protein |
rplS |
Experiment(s):EBI-893117 | ||
|
Protein |
rplX |
Experiment(s):EBI-893117 | ||
|
Protein |
rpsE |
Experiment(s):EBI-893117 | ||
|
Protein |
uspA |
Experiment(s):EBI-893117 | ||
|
Protein |
uvrA |
Experiment(s):EBI-893117 | ||
|
Protein |
infB |
Experiment(s):EBI-1145014 | ||
|
Protein |
rplS |
Experiment(s):EBI-1145014 | ||
|
Protein |
rpoB |
Experiment(s):EBI-1145014 | ||
|
Protein |
rplE |
Experiment(s):EBI-1145014 | ||
|
Protein |
rpsD |
Experiment(s):EBI-1145014 | ||
|
Protein |
rpsC |
Experiment(s):EBI-1145014 | ||
|
Protein |
rpsE |
Experiment(s):EBI-1145014 | ||
|
Protein |
cybC |
Experiment(s):EBI-1145014 | ||
|
Protein |
fur |
Experiment(s):EBI-1145014 | ||
|
Protein |
rpsG |
Experiment(s):EBI-1145014 | ||
|
Protein |
rpoC |
Experiment(s):EBI-1145014 | ||
|
Protein |
rhsD |
Experiment(s):EBI-1145014 | ||
|
Protein |
rpsI |
Experiment(s):EBI-1145014 | ||
|
Protein |
argG |
Experiment(s):EBI-1145014 | ||
|
Protein |
ycgL |
Experiment(s):EBI-1145014 | ||
|
Protein |
rplP |
Experiment(s):EBI-1145014 | ||
|
Protein |
rplO |
Experiment(s):EBI-1145014 | ||
|
Protein |
rplB |
Experiment(s):EBI-1145014 | ||
|
Protein |
rplF |
Experiment(s):EBI-1145014 | ||
|
Protein |
infB |
LCMS(ID Probability):99.6 MALDI(Z-score):32.761336 | ||
|
Protein |
rplS |
LCMS(ID Probability):99.6 MALDI(Z-score):7.861719 | ||
|
Protein |
uspA |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpsD |
MALDI(Z-score):35.151115 | ||
|
Protein |
prs |
MALDI(Z-score):26.958625 | ||
|
Protein |
rpsC |
MALDI(Z-score):28.874868 | ||
|
Protein |
uvrA |
LCMS(ID Probability):99.6 | ||
|
Protein |
rplB |
MALDI(Z-score):33.940166 | ||
|
Protein |
rpoB |
LCMS(ID Probability):99.6 MALDI(Z-score):28.301955 | ||
|
Protein |
rpoZ |
LCMS(ID Probability):99.6 MALDI(Z-score):27.410999 | ||
|
Protein |
metJ |
LCMS(ID Probability):99.6 | ||
|
Protein |
rpoC |
LCMS(ID Probability):99.6 MALDI(Z-score):26.157520 | ||
|
Protein |
rpoA |
LCMS(ID Probability):99.6 MALDI(Z-score):41.607176 | ||
| edit table |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
| Compartment | Description | Evidence | Reference/Source | Notes |
|---|---|---|---|---|
| edit table |
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
| Name | |
|---|---|
| Sequence |
MNKEILAVVE AVSNEKALPR EKIFEALESA LATATKKKYE QEIDVRVQID RKSGDFDTFR RWLVVDEVTQ PTKEITLEAA RYEDESLNLG DYVEDQIESV TFDRITTQTA KQVIVQKVRE AERAMVVDQF REHEGEIITG VVKKVNRDNI SLDLGNNAEA VILREDMLPR ENFRPGDRVR GVLYSVRPEA RGAQLFVTRS KPEMLIELFR IEVPEIGEEV IEIKAAARDP GSRAKIAVKT NDKRIDPVGA CVGMRGARVQ AVSTELGGER IDIVLWDDNP AQFVINAMAP ADVASIVVDE DKHTMDIAVE AGNLAQAIGR NGQNVRLASQ LSGWELNVMT VDDLQAKHQA EAHAAIDTFT KYLDIDEDFA TVLVEEGFST LEELAYVPMK ELLEIEGLDE PTVEALRERA KNALATIAQA QEESLGDNKP ADDLLNLEGV DRDLAFKLAA RGVCTLEDLA EQGIDDLADI EGLTDEKAGA LIMAARNICW FGDEA |
| Length |
495 |
| Mol. Wt |
54.87 kDa |
| pI |
4.4 (calculated) |
| Extinction coefficient |
30,940 - 31,315 (calc based on 6 Y, 4 W, and 3 C residues) |
| edit table |
Domains/Motifs/Modification Sites
|
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
|
<motif_map/> |
|
Structure
| </protect>
Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
| Resource type | Source | Notes/Reference |
|---|---|---|
| edit table |
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
| Database | Accession | Notes |
|---|---|---|
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
|
Escherichia coli str. K-12 substr. MG1655 | ||
| edit table |
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Notes
Links
| Name | URL | Comments |
|---|---|---|
| edit table |
References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ Kim, HC et al. (2006) Role of E.coli NusA in phage HK022 Nun-mediated transcription termination. J. Mol. Biol. 359 10-21 PubMed
- ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 6.13 6.14 6.15 6.16 6.17 6.18 6.19 6.20 6.21 6.22 6.23 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
- ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 8.00 8.01 8.02 8.03 8.04 8.05 8.06 8.07 8.08 8.09 8.10 8.11 8.12 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
- ↑ 9.0 9.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
Categories
- GO:0000166 ! nucleotide binding
- GO:0003700 ! DNA-binding transcription factor activity
- GO:0003723 ! RNA binding
- GO:0005515 ! protein binding
- GO:0006281 ! DNA repair
- GO:0006350 ! transcription
- GO:0006353 ! DNA-templated transcription, termination
- GO:0006950 ! response to stress
- GO:0030528 ! obsolete transcription regulator activity
- GO:0031554 ! regulation of DNA-templated transcription, termination
- GO:0031564 ! transcription antitermination
- Proteins
