mngR:Gene Product(s)
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Nomenclature | Function | Interactions | Localization | Sequence | Domains | Structure | Resources | Accessions | Links | References | Suggestions |
Nomenclature
See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.
Standard name |
MngR |
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Synonyms |
DNA-binding transcriptional dual regulator, fatty-acyl-binding[1], B0730[2][1], YbgB[2][1], transcriptional regulator of succinylCoA synthetase operon[2][1], fatty acyl responsive regulator[2][1], P30[2][1], FarR[2][1] , ECK0718, farR, JW0719, ybgB, b0730 |
Product description |
Component of MngR transcriptional repressor[2][3]; MngR-acyl-CoA[2][3] mngAB operon repressor, mannosyl glycerate utilization[4] |
EC number (for enzymes) |
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Notes
Function
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Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.
Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
---|---|---|---|---|---|---|---|---|
GO:0003700 |
transcription factor activity |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0003700 |
transcription factor activity |
ISS: Inferred from Sequence or Structural Similarity |
Swiss-Prot:P26602 |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0003700 |
transcription factor activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
GO:0003700 |
transcription factor activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
GO:0005622 |
intracellular |
GOA:interpro |
IEA: Inferred from Electronic Annotation |
C |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0016566 |
specific transcriptional repressor activity |
ISS: Inferred from Sequence or Structural Similarity |
Swiss-Prot:P26602 |
F |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0016566 |
specific transcriptional repressor activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
GO:0016566 |
specific transcriptional repressor activity |
IDA: Inferred from Direct Assay |
F |
Seeded from EcoCyc (v14.0) |
complete | |||
GO:0032582 |
negative regulation of gene-specific transcription |
ISS: Inferred from Sequence or Structural Similarity |
Swiss-Prot:P26602 |
P |
Seeded from EcoCyc (v14.0) |
complete | ||
GO:0032582 |
negative regulation of gene-specific transcription |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
GO:0032582 |
negative regulation of gene-specific transcription |
IDA: Inferred from Direct Assay |
P |
Seeded from EcoCyc (v14.0) |
complete | |||
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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.
Partner Type | Partner | Notes | References | Evidence |
---|---|---|---|---|
Protein |
Subunits of MngR transcriptional repressor |
could be indirect |
||
Protein |
rpmF |
Experiment(s):EBI-1137834 | ||
Protein |
prs |
Experiment(s):EBI-1137834 | ||
Protein |
rpmB |
Experiment(s):EBI-1137834 | ||
Protein |
rmlA2 |
Experiment(s):EBI-1137834 | ||
Protein |
Subunits of MngR-acyl-CoA |
could be indirect |
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Notes
Localization
See Help:Product_localization for how to add or edit information in this section of EcoliWiki.
Compartment | Description | Evidence | Reference/Source | Notes |
---|---|---|---|---|
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Notes
Structure and Physical Properties
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Physical Properties
See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.
Name | |
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Sequence |
MGHKPLYRQI ADRIREQIAR GELKPGDALP TESALQTEFG VSRVTVRQAL RQLVEQQILE SIQGSGTYVK EERVNYDIFQ LTSFDEKLSD RHVDTHSEVL IFEVIPADDF LQQQLQITPQ DRVWHVKRVR YRKQKPMALE ETWMPLALFP DLTWQVMENS KYHFIEEVKK MVIDRSEQEI IPLMPTEEMS RLLNISQTKP ILEKVSRGYL VDGRVFEYSR NAFNTDDYKF TLIAQRKSSR |
Length |
240 |
Mol. Wt |
28.273 kDa |
pI |
6.7 (calculated) |
Extinction coefficient |
28,420 (calc based on 8 Y, 3 W, and 0 C residues) |
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Domains/Motifs/Modification Sites
See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.
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Structure
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Structure figures<protect> | ||||||
Notes
Gene Product Resources
See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.
Resource type | Source | Notes/Reference |
---|---|---|
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Notes
Accessions in Other Databases
See Help:Gene_accessions for help with entering information into the Gene Accessions table.
Database | Accession | Notes |
---|---|---|
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
Escherichia coli str. K-12 substr. MG1655 | ||
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Notes
Links
Name | URL | Comments |
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References
See Help:References for how to manage references in EcoliWiki.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 2.6 2.7 2.8 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ 3.0 3.1 3.2 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
- ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
- ↑ 5.0 5.1 5.2 Aravind, L & Anantharaman, V (2003) HutC/FarR-like bacterial transcription factors of the GntR family contain a small molecule-binding domain of the chorismate lyase fold. FEMS Microbiol. Lett. 222 17-23 PubMed
- ↑ 6.0 6.1 6.2 Sampaio, MM et al. (2004) Phosphotransferase-mediated transport of the osmolyte 2-O-alpha-mannosyl-D-glycerate in Escherichia coli occurs by the product of the mngA (hrsA) gene and is regulated by the mngR (farR) gene product acting as repressor. J. Biol. Chem. 279 5537-48 PubMed
- ↑ 7.0 7.1 7.2 Quail, MA et al. (1994) Identification of a fatty acyl responsive regulator (FarR) in Escherichia coli. FEBS Lett. 356 183-7 PubMed
- ↑ 8.0 8.1 8.2 8.3 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
- ↑ 9.0 9.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed
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