mak:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

Mak

Synonyms

manno(fructo)kinase[1], B0394[2][1], Mak[2][1], YajF[2][1] , ECK0389, JW0385, yajF, b0394

Product description

EG11288[2][3]

Cryptic manno(fructo)kinase[4]

EC number (for enzymes)
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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0000166

nucleotide binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

complete

GO:0005975

carbohydrate metabolic process

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0119

P

Seeded from EcoCyc (v14.0)

complete

GO:0008865

fructokinase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.1.4

F

Seeded from EcoCyc (v14.0)

complete

GO:0016301

kinase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0418

F

Seeded from EcoCyc (v14.0)

complete

GO:0016740

transferase activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0808

F

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

nlpE

PMID:16606699[5]

Experiment(s):EBI-1136448

Protein

groL

PMID:16606699[5]

Experiment(s):EBI-1136448

Protein

rplI

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rplA

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rplR

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rplO

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

eno

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rpsM

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rpmC

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rpsT

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rplY

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

ahpC

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

rplX

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

groS

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

hdeB

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

hupA

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

hns

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

pflB

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

dps

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

yfiD

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

slyD

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

tig

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

yajQ

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

yfcZ

PMID:19402753[6]

LCMS(ID Probability):99.4

Protein

zapB

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

pgm

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

queA

PMID:19402753[6]

MALDI(Z-score):37.839387

Protein

talB

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

ppsA

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

yjbJ

PMID:19402753[6]

LCMS(ID Probability):99.6

Protein

ldhA

PMID:19402753[6]

LCMS(ID Probability):99.6

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

cytoplasm


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MNHSMIISTA LSLNLAGMIT NCRRPCIANP VVRLYAIDIE KNKESTVRIG IDLGGTKTEV
IALGDAGEQL YRHRLPTPRD DYRQTIETIA TLVDMAEQAT GQRGTVGMGI PGSISPYTGV
VKNANSTWLN GQPFDKDLSA RLQREVRLAN DANCLAVSEA VDGAAAGAQT VFAVIIGTGC
GAGVAFNGRA HIGGNGTAGE WGHNPLPWMD EDELRYREEV PCYCGKQGCI ETFISGTGFA
MDYRRLSGHA LKGSEIIRLV EESDPVAELA LRRYELRLAK SLAHVVNILD PDVIVLGGGM
SNVDRLYQTV GQLIKQFVFG GECETPVRKA KHGDSSGVRG AAWLWPQE
Length

348

Mol. Wt

37.553 kDa

pI

6.2 (calculated)

Extinction coefficient

40,910 - 41,910 (calc based on 9 Y, 5 W, and 8 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

4..193

PF00480 ROK family

PMID:19920124[7]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=mak taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111128

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:949086

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0001372

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P23917

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG11288

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG11288

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:949086

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120001261

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB1265

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.0 5.1 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  6. ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 6.13 6.14 6.15 6.16 6.17 6.18 6.19 6.20 6.21 6.22 6.23 6.24 6.25 6.26 6.27 6.28 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  7. ↑ Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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