infC:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

InfC

Synonyms

protein chain initiation factor IF-3[1], B1718[2][1], Fit[2][1], SrjA[2][1], InfC[2][1], IF3[2][1] , ECK1716, fit, JW5829, srjA, b1718

Product description

protein chain initiation factor IF-3[2][3]

Protein chain initiation factor IF3; unusual AUU start codon[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003723

RNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0694

F

Seeded from EcoCyc (v14.0)

complete

GO:0003743

translation initiation factor activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00080

F

Seeded from EcoCyc (v14.0)

complete

GO:0003743

translation initiation factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001288

F

Seeded from EcoCyc (v14.0)

complete

GO:0003743

translation initiation factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019813

F

Seeded from EcoCyc (v14.0)

complete

GO:0003743

translation initiation factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019814

F

Seeded from EcoCyc (v14.0)

complete

GO:0003743

translation initiation factor activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019815

F

Seeded from EcoCyc (v14.0)

complete

GO:0003743

translation initiation factor activity

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0396

F

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0963

C

Seeded from EcoCyc (v14.0)

complete

GO:0005737

cytoplasm

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0086

C

Seeded from EcoCyc (v14.0)

complete

GO:0006412

translation

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0648

P

Seeded from EcoCyc (v14.0)

complete

GO:0006413

translational initiation

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00080

P

Seeded from EcoCyc (v14.0)

complete

GO:0006413

translational initiation

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001288

P

Seeded from EcoCyc (v14.0)

complete

GO:0006413

translational initiation

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019813

P

Seeded from EcoCyc (v14.0)

complete

GO:0006413

translational initiation

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019814

P

Seeded from EcoCyc (v14.0)

complete

GO:0006413

translational initiation

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR019815

P

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

PMID:16858726[5]

IDA: Inferred from Direct Assay

C

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

ynbC

PMID:15690043[6]

Experiment(s):EBI-889800

Protein

rng

PMID:15690043[6]

Experiment(s):EBI-889800

Protein

rplB

PMID:15690043[6]

Experiment(s):EBI-889800, EBI-894739

Protein

rplC

PMID:15690043[6]

Experiment(s):EBI-889800, EBI-894739

Protein

rplD

PMID:15690043[6]

Experiment(s):EBI-889800, EBI-894739

Protein

rplE

PMID:15690043[6]

Experiment(s):EBI-889800

Protein

rplJ

PMID:15690043[6]

Experiment(s):EBI-889800

Protein

rplK

PMID:15690043[6]

Experiment(s):EBI-889800

Protein

rpsA

PMID:15690043[6]

Experiment(s):EBI-889800, EBI-894739

Protein

rpsB

PMID:15690043[6]

Experiment(s):EBI-889800, EBI-894739

Protein

rpsC

PMID:15690043[6]

Experiment(s):EBI-889800, EBI-894739

Protein

rpsD

PMID:15690043[6]

Experiment(s):EBI-889800, EBI-894739

Protein

rpsE

PMID:15690043[6]

Experiment(s):EBI-889800, EBI-894739, EBI-884272

Protein

rpsF

PMID:15690043[6]

Experiment(s):EBI-889800, EBI-894739

Protein

rpsG

PMID:15690043[6]

Experiment(s):EBI-889800, EBI-894739

Protein

rpsJ

PMID:15690043[6]

Experiment(s):EBI-889800, EBI-894739

Protein

rpsK

PMID:15690043[6]

Experiment(s):EBI-889800

Protein

rpsM

PMID:15690043[6]

Experiment(s):EBI-889800, EBI-894739

Protein

ccmB

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

dacA

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

hupB

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rplI

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rplL

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rplM

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rplO

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rplP

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rplS

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rplT

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rplU

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rplV

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rplX

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rpmG

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rpsH

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rpsI

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rpsN

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rpsO

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rpsP

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rpsR

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rpsS

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rpsT

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

rpsU

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

yfiF

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

yhbY

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

sufC

PMID:15690043[6]

Experiment(s):EBI-894739

Protein

hupB

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplK

PMID:19402753[7]

LCMS(ID Probability):90.0 MALDI(Z-score):17.053160

Protein

gyrA

PMID:19402753[7]

MALDI(Z-score):27.834783

Protein

rplS

PMID:19402753[7]

LCMS(ID Probability):99.0 MALDI(Z-score):4.182490

Protein

rpsT

PMID:19402753[7]

LCMS(ID Probability):99.4

Protein

rpsF

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):25.158298

Protein

rplO

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplU

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsJ

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):13.119568

Protein

rpsP

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):2.271909

Protein

rpsN

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):6.774524

Protein

rplT

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

rpsS

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsA

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):27.307921

Protein

rpsM

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):31.815457

Protein

rpsH

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):2.028396

Protein

rpsR

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rpsC

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):36.139927

Protein

srmB

PMID:19402753[7]

MALDI(Z-score):27.406480

Protein

sufC

PMID:19402753[7]

LCMS(ID Probability):99.2

Protein

rpsD

PMID:19402753[7]

LCMS(ID Probability):99.6 MALDI(Z-score):37.639394

Protein

rpsI

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

rplB

PMID:19402753[7]

LCMS(ID Probability):99.0 MALDI(Z-score):20.822580

Protein

rpsU

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

clpA

PMID:19402753[7]

MALDI(Z-score):22.184306

Protein

dacA

PMID:19402753[7]

LCMS(ID Probability):99.2

Protein

rpsO

PMID:19402753[7]

LCMS(ID Probability):99.6

Protein

parC

PMID:19402753[7]

MALDI(Z-score):28.844089

Protein

rplD

PMID:19402753[7]

LCMS(ID Probability):99.0 MALDI(Z-score):3.745052

Protein

yhbY

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

nadE

PMID:19402753[7]

MALDI(Z-score):39.214842

Protein

yfiF

PMID:19402753[7]

LCMS(ID Probability):99.0

Protein

rng

PMID:19402753[7]

MALDI(Z-score):18.226567

Protein

plsB

PMID:19402753[7]

MALDI(Z-score):25.207725

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes
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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MKGGKRVQTA RPNRINGEIR AQEVRLTGLE GEQLGIVSLR EALEKAEEAG VDLVEISPNA
EPPVCRIMDY GKFLYEKSKS SKEQKKKQKV IQVKEIKFRP GTDEGDYQVK LRSLIRFLEE
GDKAKITLRF RGREMAHQQI GMEVLNRVKD DLQELAVVES FPTKIEGRQM IMVLAPKKKQ
Length

180

Mol. Wt

20.563 kDa

pI

9.9 (calculated)

Extinction coefficient

4,470 - 4,595 (calc based on 3 Y, 0 W, and 1 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed; alternate

UniProt:P0A707

Domain

10..85

PF05198 Translation initiation factor IF-3, N-terminal domain

PMID:19920124[8]

Domain

90..178

PF00707 Translation initiation factor IF-3, C-terminal domain

PMID:19920124[8]

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=infC taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16129674

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946225

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0005734

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0A707

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10506

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10506

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946225

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000499

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0501

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 2.4 2.5 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Lasserre, JP et al. (2006) A complexomic study of Escherichia coli using two-dimensional blue native/SDS polyacrylamide gel electrophoresis. Electrophoresis 27 3306-21 PubMed
  6. ↑ 6.00 6.01 6.02 6.03 6.04 6.05 6.06 6.07 6.08 6.09 6.10 6.11 6.12 6.13 6.14 6.15 6.16 6.17 6.18 6.19 6.20 6.21 6.22 6.23 6.24 6.25 6.26 6.27 6.28 6.29 6.30 6.31 6.32 6.33 6.34 6.35 6.36 6.37 6.38 6.39 6.40 6.41 6.42 6.43 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  7. ↑ 7.00 7.01 7.02 7.03 7.04 7.05 7.06 7.07 7.08 7.09 7.10 7.11 7.12 7.13 7.14 7.15 7.16 7.17 7.18 7.19 7.20 7.21 7.22 7.23 7.24 7.25 7.26 7.27 7.28 7.29 7.30 7.31 7.32 7.33 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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