hscB:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

HscB

Synonyms

DnaJ-like molecular chaperone specific for IscU[1], B2527[2][1], YfhE[2][1], HscB[2][1], Hsc20[2][1] , ECK2524, JW2511, yfhE, b2527

Product description

Hsc20 co-chaperone that acts with Hsc66 in IscU iron-sulfur cluster assembly[2][3]

Hsc20, DnaJ-like co-chaperone for HscA; specific for IscU[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

clpB

PMID:15690043[5]

Experiment(s):EBI-889252

Protein

rpoC

PMID:15690043[5]

Experiment(s):EBI-889252

Protein

tufA

PMID:15690043[5]

Experiment(s):EBI-889252, EBI-894305

Protein

htpG

PMID:15690043[5]

Experiment(s):EBI-894305

Protein

rplA

PMID:15690043[5]

Experiment(s):EBI-894305

Protein

rplJ

PMID:15690043[5]

Experiment(s):EBI-894305

Protein

rplK

PMID:15690043[5]

Experiment(s):EBI-894305

Protein

rplL

PMID:15690043[5]

Experiment(s):EBI-894305

Protein

rpmC

PMID:15690043[5]

Experiment(s):EBI-894305

Protein

rpmG

PMID:15690043[5]

Experiment(s):EBI-894305

Protein

rpsB

PMID:15690043[5]

Experiment(s):EBI-894305

Protein

rpsG

PMID:15690043[5]

Experiment(s):EBI-894305

Protein

rpsN

PMID:15690043[5]

Experiment(s):EBI-894305

Protein

ugpB

PMID:15690043[5]

Experiment(s):EBI-894305

Protein

dcuD

PMID:15690043[5]

Experiment(s):EBI-894305

Protein

pepD

PMID:16606699[6]

Experiment(s):EBI-1143149

Protein

tufB

PMID:19402753[7]

MALDI(Z-score):20.192411

Protein

metK

PMID:19402753[7]

MALDI(Z-score):18.535481

Protein

htpG

PMID:19402753[7]

LCMS(ID Probability):99.0 MALDI(Z-score):28.837684

Protein

clpB

PMID:19402753[7]

MALDI(Z-score):28.627041

Protein

clpX

PMID:19402753[7]

MALDI(Z-score):39.634700

Protein

dcuD

PMID:19402753[7]

LCMS(ID Probability):99.0

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MDYFTLFGLP ARYQLDTQAL SLRFQDLQRQ YHPDKFASGS QAEQLAAVQQ SATINQAWQT
LRHPLMRAEY LLSLHGFDLA SEQHTVRDTA FLMEQLELRE ELDEIEQAKD EARLESFIKR
VKKMFDTRHQ LMVEQLDNET WDAAADTVRK LRFLDKLRSS AEQLEEKLLD F
Length

171

Mol. Wt

20.137 kDa

pI

4.9 (calculated)

Extinction coefficient

16,960 (calc based on 4 Y, 2 W, and 0 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

2..71

PF00226 DnaJ domain

PMID:19920124[8]

Domain

86..163

PF07743 HSCB C-terminal oligomerisation domain

PMID:19920124[8]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=hscB taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:16130452

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:946995

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0008317

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0A6L9

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12131

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12131

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:946995

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002033

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2052

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 2.4 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. 7.0 7.1 7.2 7.3 7.4 7.5 Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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