gspD:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

GspD

Synonyms

general secretory pathway component, cryptic[1], B3325[2][1], YheF[2][1], GspD[2][1] , ECK3312, JW5707, yheF, b3325

Product description

putative protein secretion protein for export[2][3];

Component of GspC-O secreton complex[3]

Part of H-NS-silenced gsp divergon, type II protein secretion; OM secretin; cloned gsp divergon secretes ChiA[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005886

plasma membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-1003

C

Seeded from EcoCyc (v14.0)

complete

GO:0006810

transport

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0813

P

Seeded from EcoCyc (v14.0)

complete

GO:0008565

protein transporter activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004845

F

Seeded from EcoCyc (v14.0)

complete

GO:0008565

protein transporter activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013356

F

Seeded from EcoCyc (v14.0)

complete

GO:0009279

cell outer membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0998

C

Seeded from EcoCyc (v14.0)

complete

GO:0009279

cell outer membrane

GO_REF:0000023

IEA: Inferred from Electronic Annotation

SP_SL:SL-0040

C

Seeded from EcoCyc (v14.0)

complete

GO:0009306

protein secretion

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001775

P

Seeded from EcoCyc (v14.0)

complete

GO:0009306

protein secretion

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR004846

P

Seeded from EcoCyc (v14.0)

complete

GO:0015627

type II protein secretion system complex

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013356

C

Seeded from EcoCyc (v14.0)

complete

GO:0015628

protein secretion by the type II secretion system

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013356

P

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001775

C

Seeded from EcoCyc (v14.0)

complete

GO:0016020

membrane

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0472

C

Seeded from EcoCyc (v14.0)

complete

GO:0019867

outer membrane

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR013356

C

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of GspC-O secreton complex

could be indirect


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

Periplasm

PMID:11266368[5]

EchoLocation:gspD


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MDCVMKGLNK ITCCLLAALL MPCAGHAENE QYGANFNNAD IRQFVEIVGQ HLGKTILIDP
SVQGTISVRS NDTFSQQEYY QFFLSILDLY GYSVITLDNG FLKVVRSANV KTSPGMIADS
SRPGVGDELV TRIVPLENVP ARDLAPLLRQ MMDAGSVGNV VHYEPSNVLI LTGRASTINK
LIEVIKRVDV IGTEKQQIIH LEYASAEDLA EILNQLISES HGKSQMPALL SAKIVADKRT
NSLIISGPEK ARQRITSLLK SLDVEESEEG NTRVYYLKYA KATNLVEVLT GVSEKLKDEK
GNARKPSSSG AMDNVAITAD EQTNSLVITA DQSVQEKLAT VIARLDIRRA QVLVEAIIVE
VQDGNGLNLG VQWANKNVGA QQFTNTGLPI FNAAQGVADY KKNGGITSAN PAWDMFSAYN
GMAAGFFNGD WGVLLTALAS NNKNDILATP SIVTLDNKLA SFNVGQDVPV LSGSQTTSGD
NVFNTVERKT VGTKLKVTPQ VNEGDAVLLE IEQEVSSVDS SSNSTLGPTF NTRTIQNAVL
VKTGETVVLG GLLDDFSKEQ VSKVPLLGDI PLVGQLFRYT STERAKRNLM VFIRPTIIRD
DDVYRSLSKE KYTRYRQEQQ QRIDGKSKAL VGSEDLPVLD ENTFNSHAPA PSSR
Length

654

Mol. Wt

71.146 kDa

pI

5.3 (calculated)

Extinction coefficient

40,340 - 40,840 (calc based on 16 Y, 3 W, and 4 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

motif

1-23

UniProt Manual:Signal Peptides

UniProt:P45758

Domain

433..595

PF00263 Bacterial type II and III secretion system protein

PMID:19920124[6]

Domain

127..189

PF03958 Bacterial type II/III secretion system short domain

PMID:19920124[6]

Domain

192..264

PF03958 Bacterial type II/III secretion system short domain

PMID:19920124[6]

Domain

268..347

PF03958 Bacterial type II/III secretion system short domain

PMID:19920124[6]

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Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=gspD taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111569

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947822

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0010879

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P45758

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:G7703

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12890

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947822

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120004248

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2727

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 1.3 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ Py, B et al. (2001) An inner membrane platform in the type II secretion machinery of Gram-negative bacteria. EMBO Rep. 2 244-8 PubMed
  6. ↑ 6.0 6.1 6.2 6.3 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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