greA:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

GreA

Synonyms

transcription elongation factor[1], B3181[2][1], GreA[2][1] , ECK3170, JW3148, b3181

Product description

transcription elongation factor GreA[2][3]

Transcript cleavage factor[4]

EC number (for enzymes)


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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00105

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001437

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006359

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018151

F

Seeded from EcoCyc (v14.0)

complete

GO:0003677

DNA binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0238

F

Seeded from EcoCyc (v14.0)

complete

GO:0003711

transcription elongation regulator activity

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00105

F

Seeded from EcoCyc (v14.0)

complete

GO:0003711

transcription elongation regulator activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001437

F

Seeded from EcoCyc (v14.0)

complete

GO:0003711

transcription elongation regulator activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006359

F

Seeded from EcoCyc (v14.0)

complete

GO:0003711

transcription elongation regulator activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018151

F

Seeded from EcoCyc (v14.0)

complete

GO:0006350

transcription

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0804

P

Seeded from EcoCyc (v14.0)

complete

GO:0006355

regulation of transcription, DNA-dependent

GOA:hamap
GO_REF:0000020

IEA: Inferred from Electronic Annotation

HAMAP:MF_00105

P

Seeded from EcoCyc (v14.0)

complete

GO:0006355

regulation of transcription, DNA-dependent

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR001437

P

Seeded from EcoCyc (v14.0)

complete

GO:0006355

regulation of transcription, DNA-dependent

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006359

P

Seeded from EcoCyc (v14.0)

complete

GO:0006355

regulation of transcription, DNA-dependent

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR018151

P

Seeded from EcoCyc (v14.0)

complete

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Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

aceE

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

adhE

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

atpD

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

carB

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

clpX

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

dnaK

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

gapA

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

gatZ

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

guaB

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

metE

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

ptsI

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rho

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rplB

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rplD

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rplE

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rplJ

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rplM

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rpoA

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rpoB

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rpoC

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rpsB

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rpsE

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rpsG

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

rpsJ

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

secA

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

thrS

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

tufA

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

yeaG

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

yfiF

PMID:15690043[5]

Experiment(s):EBI-883047

Protein

prs

PMID:16606699[6]

Experiment(s):EBI-1145055

Protein

ybiB

PMID:16606699[6]

Experiment(s):EBI-1145055

Protein

nadE

PMID:16606699[6]

Experiment(s):EBI-1145055

Protein

guaB

PMID:19402753[7]

MALDI(Z-score):17.053160

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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

cytoplasm

From EcoCyc[3]


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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc 

MTLRGAEKLR EELDFLKSVR RPEIIAAIAE AREHGDLKEN AEYHAAREQQ GFCEGRIKDI
EAKLSNAQVI DVTKMPNNGR VIFGATVTVL NLDSDEEQTY RIVGDDEADF KQNLISVNSP
IARGLIGKEE DDVVVIKTPG GEVEFEVIKV EYL
Length

153

Mol. Wt

17.099 kDa

pI

4.6 (calculated)

Extinction coefficient

4,470 - 4,595 (calc based on 3 Y, 0 W, and 1 C residues)

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Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Domain

80..157

PF01272 Transcription elongation factor, GreA/GreB, C-term

PMID:19920124[8]

Domain

1..74

PF03449 domain

PMID:19920124[8]

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<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=greA taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference
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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111554

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947696

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0010454

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P0A6W5

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG10415

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG10415

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947696

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120000408

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB0410

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. ↑ 1.0 1.1 1.2 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. ↑ 2.0 2.1 2.2 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. ↑ 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. ↑ EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. ↑ 5.00 5.01 5.02 5.03 5.04 5.05 5.06 5.07 5.08 5.09 5.10 5.11 5.12 5.13 5.14 5.15 5.16 5.17 5.18 5.19 5.20 5.21 5.22 5.23 5.24 5.25 5.26 5.27 5.28 Butland, G et al. (2005) Interaction network containing conserved and essential protein complexes in Escherichia coli. Nature 433 531-7 PubMed
  6. ↑ 6.0 6.1 6.2 Arifuzzaman, M et al. (2006) Large-scale identification of protein-protein interaction of Escherichia coli K-12. Genome Res. 16 686-91 PubMed
  7. ↑ Hu, P et al. (2009) Global functional atlas of Escherichia coli encompassing previously uncharacterized proteins. PLoS Biol. 7 e96 PubMed
  8. ↑ 8.0 8.1 Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

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