gntK:Gene Product(s)

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Nomenclature Function Interactions Localization Sequence Domains Structure Resources Accessions Links References Suggestions

Nomenclature

See Help:Product_nomenclature for help entering or editing information in this section of EcoliWiki.

Standard name

GntK

Synonyms

gluconate kinase 2[1], gluconate transport, GNT I system[1], B3437[2][1], GntK[2][1] , ECK3422, JW3400, b3437

Product description

GntK[2][3];

Component of gluconokinase I[2][3]

Gluconokinase, thermoresistant[4]

EC number (for enzymes)

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Notes

Function

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<protect> Gene Ontology
See Help:Gene_ontology for help entering or editing GO terms and GO annotations in EcoliWiki.

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005737

cytoplasm

C

Seeded from Riley et al 2006 [1].

Missing: evidence, reference

GO:0046316

gluconokinase activity

PMID:7815304[5]

IMP: Inferred from Mutant Phenotype

F

complete

GO:0046316

gluconokinase activity

PMID:8925917[6]

IDA: Inferred from Direct Assay

F

complete

GO:0000166

nucleotide binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0547

F

Seeded from EcoCyc (v14.0)

complete

GO:0046177

D-gluconate catabolic process

P

Missing: evidence, reference

GO:0004765

shikimate kinase activity

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000623

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR000623

F

Seeded from EcoCyc (v14.0)

complete

GO:0005524

ATP binding

GOA:spkw
SP_KW:GO_REF:0000004

IEA: Inferred from Electronic Annotation

SP_KW:KW-0067

F

Seeded from EcoCyc (v14.0)

complete

GO:0005975

carbohydrate metabolic process

GOA:interpro
GO_REF:0000002

IEA: Inferred from Electronic Annotation

InterPro:IPR006001

P

Seeded from EcoCyc (v14.0)

complete

GO:0046316

gluconokinase activity

GOA:spec
GO_REF:0000003

IEA: Inferred from Electronic Annotation

EC:2.7.1.12

F

Seeded from EcoCyc (v14.0)

complete

Interactions See Help:Product_interactions for help entering or editing information about gene product interactions in this section of EcoliWiki.

Partner Type Partner Notes References Evidence

Protein

Subunits of gluconokinase I

could be indirect


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Notes

Localization

See Help:Product_localization for how to add or edit information in this section of EcoliWiki.

Compartment Description Evidence Reference/Source Notes

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Notes

Structure and Physical Properties

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<protect> Physical Properties See Help:Product_physical_properties for help entering or editing information about the physical properties of this gene product.

Name
Sequence

at EcoCyc

MGVSGSGKSA VASEVAHQLH AAFLDGDFLH PRRNIEKMAS GEPLNDDDRK PWLQALNDAA
FAMQRTNKVS LIVCSALKKH YRDLLREGNP NLSFIYLKGD FDVIESRLKA RKGHFFKTQM
LVTQFETLQE PGADETDVLV VDIDQPLEGV VASTIEVIKK GK
Length

162

Mol. Wt

17.993 kDa

pI

6.7 (calculated)

Extinction coefficient

8,480 - 8,605 (calc based on 2 Y, 1 W, and 1 C residues)


Domains/Motifs/Modification Sites

See Help:Product_domains_motifs for help entering or editing information in this section of EcoliWiki.

Type Residues Description Notes References

Initiator Methionine

1

Removed

UniProt:P46859

Domain

17..172

PF01202 Shikimate kinase

PMID:19920124[7]

<motif_map/>

Structure
See Help:Product_structure for help entering or editing information in this section of EcoliWiki.

Structures

<beststructure> gene=gntK taxon=562,83333 </beststructure>

Models

View models at:

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Structure figures

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</protect>

Notes

Gene Product Resources

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See Help:Product_resources for help with entering or editing information in this section of EcoliWiki.

Resource type Source Notes/Reference

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Notes

Accessions in Other Databases

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See Help:Gene_accessions for help with entering information into the Gene Accessions table.

Database Accession Notes

NCBI (Protein) (EcoliWiki Page)

GI:90111591

Escherichia coli str. K-12 substr. MG1655

NCBI (Protein) (EcoliWiki Page)

GeneID:947937

Escherichia coli str. K-12 substr. MG1655

ASAP

ASAP:ABE-0011224

Escherichia coli str. K-12 substr. MG1655

UniProt (EcoliWiki Page)

UniProtKB/Swiss-Prot:P46859

Escherichia coli str. K-12 substr. MG1655

EcoCyc

EcoCyc:EG12629

Escherichia coli str. K-12 substr. MG1655

EcoGene

EcoGene:EG12629

Escherichia coli str. K-12 substr. MG1655

NCBI (Gene) (EcoliWiki Page)

GeneID:947937

Escherichia coli str. K-12 substr. MG1655

RegulonDB

RegulonDB:ECK120002341

Escherichia coli str. K-12 substr. MG1655

EchoBASE

EchoBASE:EB2513

Escherichia coli str. K-12 substr. MG1655

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Notes

Links

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References

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See Help:References for how to manage references in EcoliWiki.

  1. 1.0 1.1 1.2 1.3 1.4 1.5 Riley, M. et al. (2006) Nucleic Acids Res 34:1-6 (corrected supplemental data from B. Wanner)
  2. 2.0 2.1 2.2 2.3 EcoCyc (release 10.6; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  3. 3.0 3.1 EcoCyc (release 11.1; 2007) Keseler, IM et al. (2005) Nucleic Acids Res. 33(Database issue):D334-7
  4. EcoGene: Rudd, KE (2000) EcoGene: a genome sequence database for Escherichia coli K-12. Nucleic Acids Res 28:60-4.
  5. de Rekarte, UD et al. (1994) Mutations affecting gluconate catabolism in Escherichia coli. Genetic mapping of loci for the low affinity transport and the thermoresistant gluconokinase. J. Basic Microbiol. 34 363-70 PubMed
  6. Izu, H et al. (1996) Purification and characterization of the Escherichia coli thermoresistant glucokinase encoded by the gntK gene. FEBS Lett. 394 14-6 PubMed
  7. Finn, RD et al. (2010) The Pfam protein families database. Nucleic Acids Res. 38 D211-22 PubMed

Categories

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